{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022On4g7xg0LowbGSC3jc6aivBXq7Y0N+QLfwzpbzVJ3lIU10Ow51Z+U57wbP0IFzgBvxOTkyA4KIh2aZinsICLfiJEcFSj6O5qJsElf0+8Fy55q89OiqC1fPUa3qRQbqaFw\\\\\\\\\\\\\\\/uy6vSK7zt1iDflqp3YOApTEFZjFBT9gEZjbAOeJ6oQrclEMLsJfICDGyaOHR6gWCbHxM39odTWpdyR7INGalcN+rN+3Ngmo6qPiBrxLOJZPg7FfqBLt3U22Wj3u\\\\\\\\\\\\\\\/60aCTdu7c7y0xploW7DFcOaAnVRZZ0g\\\\\\\\\\\\\\\/3iuUYZNPuevA4rYxZRp3Pjy8eIvoZF1uLi2in\\\\\\\\\\\\\\\/7KOnsFkxjxCxTIjiMa+3+JJwvMyQJK155FJCBPKmNhB\\\\\\\\\\\\\\\/bDVKZPchXJHaQlQ6S8T518onH0o5Ehfq6k21ObD\\\\\\\\\\\\\\\/w7DNrFsE6HgSMqkYMo0fDnj8thAIovcjxgh4+ltH21iJUAFBnsJt8LkA9x5flzMuQXzu0lBiN20QHjMSCd+RbFkzYNOrcktiMM6hUpcCws1rhjbdygJJGR9JdT6rhqP26F2J7kuW2GR1BCCfOHffd6dduwYBRdh+6shFEqt6J2pWN3vxZiH66xjAB9Ahonc1KpeCTUy9ataOxphMQOw6pebjvQOB3tC7QBn4a75+y0cHw1pOoR8WFNra0svYVFzKpZIQjfLK1VbWSkme9QWxy\\\\\\\\\\\\\\\/ugA+mveDTffsu25WYtLzBV0R1kXo1l\\\\\\\\\\\\\\\/2JMoQNXkLoj3p9VKFgjMjdvp2nPq2N23vWINESc7mQNni\\\\\\\\\\\\\\\/hsWWbxplMa5vP1qH3e44PpigQIq6Mz7EM7E9ClroKAhd+i2lbga6o2bs+XzWvtSAuT\\\\\\\\\\\\\\\/mIpwE2Ch+DDh9PnKgcrKu\\\\\\\\\\\\\\\/n1lpdySAcCDoZ0xKRbO01wLQ9QTCDTps4k2ke9mVJtSODqsF8Gu47qRQalgVXFhv0eG9Mva6cXsF44f179iBLulNSeji1k318TbFsFgCr5o15XkjLSHhe3C0MBvPY1i\\\\\\\\\\\\\\\/y0OU9aY6T+WJZrVvwZN\\\\\\\\\\\\\\\/td\\\\\\\\\\\\\\\/91teM9aaoQUL5SGjpAcT8DpRJkWIPUkxe11T0wyat93rx+uQe7hE7heGkZmflliHVkqmTzm7fWVGlsaOxoMaLkGyTBQsc0T8dxfIHxcAaI5PJhCdOVRb+ukARiZxazXBq5ylH7hOHY7iWyf3lH70ocBCEJh1k7yKM0aPoOCmh+vOdmGgk0wQ6hlXdKtdr5Uq9ud3WEAm6bDp628lSP5QtRuDEjjZAZ\\\\\\\\\\\\\\\/w6gCrQJKNQqbE7xdu\\\\\\\\\\\\\\\/Bj\\\\\\\\\\\\\\\/YTD5GxX+wFstkb0RmfGU4IWJKGSx95EuT6ZtaxphqX7vN5VE36rrxDUTSMjfPwySjZSLoZQqPx4lMKaadm\\\\\\\\\\\\\\\/e3e3pUz7qJZ5R40LcjEyP6T+LolWpRZE5kNZ0+N+6AvLNCHfn6zFAW993ny2jWsyVZ0dvrlbjss3XzPjtYO9Xq5QPzAxlXBdvTc6XKXn7gYA4eNdSfHtJjWIPl4AzuSRUwRyqiTmI95xsWqTRI7EyO65za0DBQLo8rJGFsFylv99eQvp\\\\\\\\\\\\\\\/XuUiCRAJhb5uhRGCHgT8DsgSurHVEYkZ0JK23TIkFNEZXo16GzslET8fMrm7Zn99F08V1ry9qoatuUHA0dVnpsZ0xkXGCU5AghA6X5GpAmSbc4vwG0HmeF24aNYyHF6CMlM7hWE3I4Y9zzkMhfNOuIUPodAD1hcVtXX20xrH081ih7c7YClkDFTZfJ+SxtsFPIJswW8bqImFhMVY17kQNnc9Ma+najN2Ebv5mXToewUKSke0KRElKLtxUHu9eQ0ZAfbnMrG5HxP4kyahlHW7RPWD+UE3Fvbp6ZRZIkmhAPYiqL2ULGorzERxqy5rCUbtujsIBGNKkojLNlfz5bX5n9AHt7SIJNfFAo3p4yX+VhcQwQltHDGcFzPbrvWpSbuasziQBEeMaQ6w7WgBzTUl\\\\\\\\\\\\\\\/0qbS32ZV41octvzj97wc1tpl3YpmhPf+Vj+rlGsjgmqyTYTKkO48gOc\\\\\\\\\\\\\\\/glsBF3N\\\\\\\\\\\\\\\/5yHWC96nPf67Vc5shDr97z6gB8mhn5p9T4YDhiB7pPBwR1nSxL5\\\\\\\\\\\\\\\/ASnQE\\\\\\\\\\\\\\\/MDtJbEsmQ+6WJsrBhCuBbmbGGZd1pJNjrkndYB8uLHRQaJrBqWqk+f4CowTgzD1YFU4IRfYa3blWJ9BvkVjbtlQsqzDbcYyxdpP6hvZFGtLPLVgDtMs2F7iLg7VoAvCaN7A3\\\\\\\\\\\\\\\/EEblLBXt4qYtmDs8pi0K\\\\\\\\\\\\\\\/B4K8v2NedNMN1IDiUkDYARZqXWq9kMs2cmCeNdpG3pgwvF2+R94FhYoXysLj4Jc0IpHCAIH39Swf7mPFPWHO4Jvv3eiL5NGtqK3gDLRMJes6Xt3Mreh2erADH\\\\\\\\\\\\\\\/viwjaCinHSwA759emwgnl+dr0RUNscUGvP48JmjCbb2vppJc\\\\\\\\\\\\\\\/E1VBfmRDbRxhCDTUnCZenS8jM0dJowJUkjWxcxqRkoCQ3IotkLGhOC\\\\\\\\\\\\\\\/VkExg6Iu21nY50t9gichwTVeoSBtIPNYwsp0pTjq330RvogYbGBNLl3XYcJxHSA66oZ3PwwZwQNsh3DIFratq0Beo9UTpBd6PasPU3m\\\\\\\\\\\\\\\/Q5WA\\\\\\\\\\\\\\\/muopzW\\\\\\\\\\\\\\\/YiEWwheZ9mrBQEXN6+bgzvCR9PJtlWIfCNOptI3UMfcYIRrawIr4SiAHZQBqtnsgfA8ir+XCM=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022aTmUObz7T5WOuEzUSTA1Ng==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00221b67792617028ecddfc4c1971927dfea6d6d1f47b8de01d6ab2611c4906c531a\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A899.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A899.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0801\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0801\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0801\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}