{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022cq8e71eW25r8D4ManhS6FI8Xcag98og7vni3+J3F3SzDfvu8YPZu0U4XK\\\\\\\\\\\\\\\/L4ahn0alIouFd9NTo6Z6vkz7SiL88\\\\\\\\\\\\\\\/74x9zf7ldziUXX0vWtoOeiJ4j3Ahl2jhmg2aosQoHS05iFJ17n9XnQkl4e9oMCMFgSKKit5xoE9M47rY+O\\\\\\\\\\\\\\\/eltO\\\\\\\\\\\\\\\/jNA\\\\\\\\\\\\\\\/5KstBcz1dVOuhWIaHE5ClBvB65qJqXo\\\\\\\\\\\\\\\/FgLfXCazhW4edvtkK9LWo72OBVe4EazhTdKNXCpwy6YuoBQ8s7b2nJpSYbVxCsEJU38bszixmAbpzKCC42aZbY+LUzeIJymCszh2T0veoziSFKVTtw1eaL+ad646RlA1\\\\\\\\\\\\\\\/3eekNQssXUAwfAQN8a9e3JrSpANH0wbQEIbhsfBp3R5piYGoArKDw+BYX\\\\\\\\\\\\\\\/8VSFYfpNx48ZmiGVgJTPHXScGDqaxmdzWzrirUAVhTc6HREAQeUc43QbDLnpJtThO4tuNLsW2Y+VrdhN9WAgmxIgT7GP1GJw3z46QXSTbx0QSEtOSE\\\\\\\\\\\\\\\/AlUWsI9uovzoh4mie+s40Ai+AGgg3wwDDRWKvcCxy16nMgQ\\\\\\\\\\\\\\\/nd6j4Eh8i+wOd8YfbR9\\\\\\\\\\\\\\\/V+tWc935oIR9UT2dcV1WwQlWqFWmCeE9H3b5KgsAs1DuYrRkcnPj6c4ontaKq\\\\\\\\\\\\\\\/FhhBReqE1UZNY3JJYBzhnd\\\\\\\\\\\\\\\/7w5OTim0NjP5QVzGYtMFJ3p+wKPODBaHvrGfZhVQp6+UWzqNxqRt7NFV+lJ4rZBeJyu8wfTgWM85ZGXn5MAmVj+l\\\\\\\\\\\\\\\/u6lz3TBHKFm6S0tJiqgr86l6v6c4Ej88OkzoLuVxDqS+aV0IGMIr+6wU7BHxYDWmdX0PAXga906Qz8QrB9k\\\\\\\\\\\\\\\/hGKWvkpfsPj8de168vEumRtTAofESATmCTXtoZkEJ+FJn1JixjuXmncyd+tYonAy+sTaeNsqT4fDXsQI\\\\\\\\\\\\\\\/MmMltHNxG72QK5s7fgAHk5RvwHd5MCY\\\\\\\\\\\\\\\/UpKRFz0rE8DVfXOSWz7TQGUAkRg1et+RQHZnvhNklSig3m86SgrgQ2bM7sQlnLHaBrI2rIDjIkOyX2jnVZxsOFdzG6f7Jll+IjVL9kLMSedmfgEupmb0ekAyPS5ppHm14RL4OmMEALCV05gv35a71y8JF0XPUYRmQXwjCdo2QlDOPgRNSUKY8u\\\\\\\\\\\\\\\/V2YkLlYR4B8kwpNbyO9YEv1fyefE1XSaRNdBqzMXseFNRNUfXBKtgcEcjE3hkaIv5z2B2lTArEWOzu0mhoTL4Sc+FoJ0pJ3WtwLf6waHJ\\\\\\\\\\\\\\\/VQcd\\\\\\\\\\\\\\\/rVblfLEAXIEi7gMz\\\\\\\\\\\\\\\/CWYlbgHTkRLjtWDXqERvapkdTsWwNUlUHFPswiN7\\\\\\\\\\\\\\\/xcTtKIqA1e5P6MYCLksM6sSUJuklfgm3DfGKAjn8am5GVlOGsdBdI6Ck9ZUTTW\\\\\\\\\\\\\\\/qcwhtFFsav1OLnJtEzDdZmytuyNUD\\\\\\\\\\\\\\\/vlYCyzfhokP4PrtfCuTW611YifIEfe9vxX\\\\\\\\\\\\\\\/Ecp4ca8JBUgftzBA6GNv+RDBZtmvD8OXwRgqxenBqchcZtg\\\\\\\\\\\\\\\/UAH0ltnXM7LMNYWgrcHj3d7\\\\\\\\\\\\\\\/2Bzgq3pZgZKWV4IyRHJoMiHmM6ENTwVQwGytb70NfTHMDlrCqncu2RH0yYCEiJTolfx0mooIXy3AWZ19JGQ2L3ewgPprykmwjvDJdb4R0JTIUuTO25iRWCvvbFq2ae+L5QDEX0HDjmGVfdaEhuFwGfrM7F\\\\\\\\\\\\\\\/KHySoiq6qL4bJtysj2gvNy4GYpJvPOEDFY1tP66WnHTaRWzVxBzEXl159w8RE88vVEovFL1AQNnnFDuAqXb3Lh+MOwXaSstLAafirW7k4mxwQPEOtRu2LIYc2rEmw6UTUqU7uuwmMMRbCspk2EM0YUd1qMuYgv62OUqnQCz3p+PsxvXwnZL42KV\\\\\\\\\\\\\\\/GrDREBNbIKQ4E+E1KwsM23ogNWTtFMINQe8pRPcVWH29ijmYT6+ZsY6cMds5YKyVDK9Q\\\\\\\\\\\\\\\/G410VYQlhUnVPJQUlnqQJ5yM7FHhQIG8g2lGBQ5SLISACiW9NVW+vIPVq4qrjXZcJ2g4QjXRRj2FsSpnpJuMBTMsDc1SLLJLNfEeg8xkhnyp67vwUrOrHY204LiTJgyKFyvp0d407pXwmFqPSemImq+79\\\\\\\\\\\\\\\/qgZ9lhcKEdAazUkTVqKxEFf+RqVH3d\\\\\\\\\\\\\\\/UoDI26LWNfDP6GrN539StpZxQYMB8dCAu0fD2MBL2AndlHoeljcAC00CMj+YX2kTCWczlBZgFsA1x4Vq\\\\\\\\\\\\\\\/WW+LWhNxtddeYnzqrdswtV5bcW4j9zqJut3lT7KI7iHQSr5daNWFPa5E+rrUUgb4nf9mWiLBQjjFfebt46yNugyBvTIfclRLk1MF521SKLbwMJeMo+lNIxw0Dd8QOyQMyPdLUxqVWF6d7au0aTDh7+uI40T9LVsK1lXGlSjaCHJb2Kd\\\\\\\\\\\\\\\/YEkp9L65X966xwzZRqBbriCBDGttl6TKdklNcXsNkzA8vS1HxqG1Rd3l2p6s\\\\\\\\\\\\\\\/yk1uvXGysCcnVv5L\\\\\\\\\\\\\\\/mZqBA0\\\\\\\\\\\\\\\/6sKwH2z6zZ+7eEm9De18dcxVSO3groBQ3J45yHuSY3VRWfkKgpNcWy08arKe9CN0EP4+dGWyi53luFVn2aC7nlPXnEtI+D\\\\\\\\\\\\\\\/56Xx3IzRtcrCgOjiWjXc7YvRyPLhbKpDzOGvvYphtHjOZEV+GFByLIz\\\\\\\\\\\\\\\/mXowT0L6P2co=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022VH4Q2MIxWw0cvIEjCggCDQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00221d12e63745ec862a9e7a6038982e7168d088f0d8257c8c2e6bc7dbdf03b7a774\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1001.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1001.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0899\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0899\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0899\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}