{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022dND\\\\\\\\\\\\\\\/r8FBqWhW8QPtndH2Ia51OCWjbOtcvOPpm3w6rjHW4yqMGS6LNiVAu506flOgC142zsUlFK53imSiVffgXNAjDMHx\\\\\\\\\\\\\\\/l4AWgEZgwAr2\\\\\\\\\\\\\\\/cvgBB85G9\\\\\\\\\\\\\\\/Gxfl8GkeJEu+85pjIidK\\\\\\\\\\\\\\\/Wa7zUv6bEOvBHrJ\\\\\\\\\\\\\\\/3UPcKg+OXsVTnUCWQ8hAvvBH+MtuErlZOeYKZi8ByMCTE9Cvq1Y+HcmOFTo6sglaKgzHjq8DRMRWr+8iUarv+G8iFOL6Yo5dReqLI6lAzBysvK9TKx1F7EBBNFq2TrGoGPpfHq\\\\\\\\\\\\\\\/F2OOmdpVKV\\\\\\\\\\\\\\\/5D1BSlWjtj11ZlrVzH85Eo049oo9Kz4PHFB2yzmc9jz9LUDKHMQ7w3Y+dEN6YRausBd2ZbleXUbRSRW1DVTPouy\\\\\\\\\\\\\\\/zdi94QEiwucogAsM7M2zMc3TovUKiTJcxDyzR2ZNA3UKp44dzfNQhj\\\\\\\\\\\\\\\/Agy0ZwjBkNYSAkE\\\\\\\\\\\\\\\/iqVjuZxeOHgqBJJn6ts+cPs\\\\\\\\\\\\\\\/l9u7XGT89n75jokvRz3QQgLyLCyaUd34ZS8AFnchBXbNBWJ3ZjqGuvv62IksXd7wU\\\\\\\\\\\\\\\/QS3gCdTQQUPlfPOu1JpGTuOuT6OKdfiQPu+OAlBSEg8nroNDIJh991M\\\\\\\\\\\\\\\/XCOcXZH2XxG0GndMNpZjr5oBvioGthb2tKJId2ElIiHDFFBV3Tt16xFFuiJ+gM3CG9b4cQLccYICF8eNI3TplwKYo6KvYLq8E4t3cCW69VusgvXOS6TbIMAgrZ\\\\\\\\\\\\\\\/+Yg5LGZgSk7oqXRSkGg3r1eBGAPBEyCDQOFo9EDgybfGO8I91fo7ljuywHDTAAF+4WcB\\\\\\\\\\\\\\\/nCDwtdR6ips8OLaKBYl1FZzrNTRBIKysxIytcm4+NgfOBIa7etNqShQS4SKW0VSoAmUVnq93KOgMGrcdBWG3YA\\\\\\\\\\\\\\\/hzaboNwPPekMzsWxdc7MyrdRuUx++16+Aum9h7KKvdxANvSC9C\\\\\\\\\\\\\\\/dPYRG\\\\\\\\\\\\\\\/fFh3uiBy27fWah1iv85r9+jaK1fqtv8U6sbRC8WLwEvmwJukbh2pfx430msBKTrNUmv+djFapP073gB0FPFm1\\\\\\\\\\\\\\\/LMjf0l2wbAWLBmTpvFdV2T0yn5kFbHbpSHFRMzQYszg+CHCpe5cQv6XEbktZKgtRNhAuCOqm4wqUE3M2KQleJqq3bK1VGyiK4U9v7ZH3a4beYPjA\\\\\\\\\\\\\\\/ZqEiVZMFYbxG3ajLZ+raJyn7hWtjXSFlBYgR+8YgQFSN3y0LSeqVhf7dMlwRB7HxRyC72yFl9mokdxzJdhk8cSrduIGEwXAzFYvr4a2Md\\\\\\\\\\\\\\\/1lykvC3lJAlBByPXqv5ePl\\\\\\\\\\\\\\\/9GM59+z7KHXtHVa7StbctVeFgetkKuiRDV9ES4ZwU1woyfREJy2YzdY+CaFVI+MqgawbOCt4mQ0c0t3qhUboF0rYcX36gUNgl+XTRVBhvtcHCxtQwfkMVpmd1\\\\\\\\\\\\\\\/LwwAW+oxZlbYUdOaVTPPrDk8rBQd7IGoI\\\\\\\\\\\\\\\/HGlbdmgmgRPjP\\\\\\\\\\\\\\\/+jlSdcP\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/pRKD6nnI3rQcJ3HcNWskmFYL25aX0wJTaS3YdJ8u29qyBn9cW\\\\\\\\\\\\\\\/f3AFo\\\\\\\\\\\\\\\/DFDV\\\\\\\\\\\\\\\/5HvEUWNsrrI8cR6PT0a4b9xwKqU17FeMSP\\\\\\\\\\\\\\\/AGyHnFRnOXx83kQVqhpeGzJf2xIXfuw\\\\\\\\\\\\\\\/TnHJf\\\\\\\\\\\\\\\/tJQTF79mD4KGlE\\\\\\\\\\\\\\\/gPnu93DPe4l2EeJLQ6tWlpoP5+ZVjg1Hw+QdfFbQvtggKo8X1\\\\\\\\\\\\\\\/6CXbHuF2hWgblxccgyss6N9\\\\\\\\\\\\\\\/Bo4MHobgGDz7n52LPw\\\\\\\\\\\\\\\/ZSlAnP9kAjYz5kS1NNzpqQz8GqK+U7vNsZetpTPVFSvEpuEgmX+UzD\\\\\\\\\\\\\\\/zVNxowFOgceBAWcf\\\\\\\\\\\\\\\/AUzIa1NZfUGCCoceM5jT04eQlBsXIAl4ne44v9wqgxfvsW4mwjy\\\\\\\\\\\\\\\/pFPODRFekiGyQ7rW2tgBYFaMiuqME5JH1KuRE1WlwHHF9lMLGsmUDnf9d8AYEjGqp4ANTaQgSQxB\\\\\\\\\\\\\\\/yur5fo19bk8BsydxqQMyDI+4OeO1wUUVQGL5JblZllaxM62nQwbySELjaCxJsJF0Uwg3XIPSVWSD9kPrxDfqu492n18TzTXrbAHTGt\\\\\\\\\\\\\\\/0pzMr7T6\\\\\\\\\\\\\\\/KOTWkDpfttLCsvLzC7uJWEy3v9CBPlLWJso97Vspoxp5J5jHVCL4rzNLlqpXXJVUxQRfEK1SWz6y2QyhQK8ac5Vg3WhWSAJGGShvemMTwte3XTYK4aQfVwFaN0+ZszukZx+rvlnvANJ9rpO1Fi8KBcHQ7Kkn8nVXu59tHG9sEZxuXX3xZs5W41d9tALFmA1bOR8+Qu8Zdb5HDjtrB4w2m6m4UUd96TmvewmlHmgvgLlzxG4\\\\\\\\\\\\\\\/9+tysPzZ5kVqBLCd\\\\\\\\\\\\\\\/qvy90EkAXxRhlXpxqiIEt142kouUu1XpnPfI9nxzEYQWmuF3NvwNdbqAulfn4cXafWmOK3VFllshzakiQC7Xvi+yUAnv7zqp0HjRj+hpZ2WxSyDu\\\\\\\\\\\\\\\/MplibyuK4nycwsN8T0LdZPfn\\\\\\\\\\\\\\\/aJ64ceD2H3TOwYiHYy4iC+rmgK32HFKq0reZjH0gutBhK+M5809DVonVFO+c\\\\\\\\\\\\\\\/rNgppaEEh5ex\\\\\\\\\\\\\\\/rxdrK6UJ7kpa8WYhAZtBo7Z6QFOGBxHq47TNOf+cYCc88LE4wURX3xN1wfasuI\\\\\\\\\\\\\\\/z\\\\\\\\\\\\\\\/347NqIjH7v6gReqCRRB9ChFMxoLEc83hu7Ilj8IRqs9b3Xj0a1nLk0YdAeQsQ88KfHg=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u00221+PIJlIaovvgmidJ6G\\\\\\\\\\\\\\\/qYw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00220563031f7e85c77edb28f7f29482e27e70fc992ba9420414f59ccf52b895e74b\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1459.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1459.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1311\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1311\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1311\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}