{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u00223pD1OerXwWgPLccloQpvPn3P0GztwZisEGst7JXd9iMZeQgCPqhVy+3NH89MsB2rfHSotUgKMnapFzUJ559BRbA8OHTR5MWd9\\\\\\\\\\\\\\\/xP\\\\\\\\\\\\\\\/OOcmCFn49mqTLG3A5c7bDf7GmjKtiuCpTECeXbEu\\\\\\\\\\\\\\\/BJwE6LQdrG62sVXzAKodt34AbLyKdWki\\\\\\\\\\\\\\\/T1bn+U1o5CthAJtWDIW+opbd7drjj\\\\\\\\\\\\\\\/XwhiO4P7A4XA6l4VIVRNCmgstSWWyrfcttuAUNrhRISWXprViQlzwdLKy+B2QvaIAgOebXVjdQ2xcAzHTE25u+yQ2bV\\\\\\\\\\\\\\\/V\\\\\\\\\\\\\\\/2SMcBbYZKkm7Uad40MwWGdE9DRFxF8st0wORGIDMlFlJHke2C+BsAsdQiMsdescANPRfnwl9C+wj2S0Qq\\\\\\\\\\\\\\\/BoJPZmeIA57svOv2AIYrEbmJcjoLae2ZJrqbqaFvJTp9Zw6KRzvhQVREqnVHlw+6vcsDn1gvudrknz\\\\\\\\\\\\\\\/toylqhjjDslnPhlSE0ItmbvhaoNW3fst7hj1ysUf5q1USJdOoDtgZ7JTyqDwbNAqc+\\\\\\\\\\\\\\\/Y7NFlEdMgRu97lZ\\\\\\\\\\\\\\\/pB0bS1qZ2taCT0ODzWMLVmL6\\\\\\\\\\\\\\\/5bEr8pNUT86mtHpQlDUh+UUoGGxLL7\\\\\\\\\\\\\\\/O1iUqTNnkjONue4k90n7efYgGBfzup\\\\\\\\\\\\\\\/S3F1fV5Re620X98G0grtTi0OUH+XNE7NRNXFrJIJjQoiyGlato+An5l9sJxDDxLvIb7GsneYyQmR8yVqDv+vgTgTw7hASpzuGQBBG\\\\\\\\\\\\\\\/C6LTINstXr0p9pzr6X9XiiUv6JkOJu67wtocaPAUs22Ulasww\\\\\\\\\\\\\\\/MhuFhLWmH6eyz4NcCkWszwgUk06o0nwPGLLwi6dWXrSSGFUTpBZQ\\\\\\\\\\\\\\\/B0ypbtAdJOTqeqDajRvZX0QbCjtkNJYjHwdq8N9NEPS\\\\\\\\\\\\\\\/07QUZ+EQ5pZqM8pU9PjKF09tL62mApO\\\\\\\\\\\\\\\/ilGAY4i3ojENvOYForkcjNpj4ZIqr5l5lffkQkTeBgkWDIjKm8R+juP4+P5YaE7YgEz1ieOc16nOsSabdtPd+odRIjV8nQBhcePIkt+PzYGGL+pUVTIDnGs2WnSi3\\\\\\\\\\\\\\\/sqndFyByPyATPPVCxLCzjPIzg+YXYTASP7NeOJV1C09Sze2BVMcwv+ors1HjqYHjJUAOpBLD7anQ\\\\\\\\\\\\\\\/fUMmQwKQ7Lp004ChtfG6YydDmk+W3\\\\\\\\\\\\\\\/wtg5ISohiDt50cSenZTghtRrcG8b58WqSP5bOK7n\\\\\\\\\\\\\\\/4XZOHj4H8F7QpzLoDHYykGbl760sDn24zpieJG1V150LkcoQtRnV\\\\\\\\\\\\\\\/qAhRmH7dDyEuWTQrCW0HZq79NDikHa0QcGxy31r1k71v5JCJkQrPNig+pONnjASEsHpAYmjq1WDvF4SpRYwFMDwdOKdYcF3gKsbvkwvP2n10lspe0SfHWYdgWrAKjFb+rN+5nTovEWOBOORbtN6g0wISSycVASfTpxTRRxfFcVJxa5rrxnC08Db53cOGNNkSwpt5G0r10C0pCrXs\\\\\\\\\\\\\\\/yPHswR36mHT6tX+aFbXQLbhd20x3VVNnXYybpADMDcS68MUYrtsfHwuMf4cDX1+AZPvX1N\\\\\\\\\\\\\\\/BR575WC\\\\\\\\\\\\\\\/3lxkj8S+Lgj+vc0TetmQt4fAdgCe\\\\\\\\\\\\\\\/j1ClcNVvK7BsHqX+A1DR7XwlE6YAIN1zhw\\\\\\\\\\\\\\\/gY\\\\\\\\\\\\\\\/RFth9BjtWjcNzVkLj98PNctNJ81A5h4pKBMut05oagG0hIhwICfbnWUs3w1fNN9RXDPpKOhGwi+9sUtkhkwiH3wdXki7uB\\\\\\\\\\\\\\\/w3AIrZg6Dioy4wjx670FP9NxikrtDBwJejoLFC1X5lnV2DKsNES6H53HdjgsLUUbmRBo8QEjGl+hVbLTkkyvd\\\\\\\\\\\\\\\/KFnrVmEpLBla0186ltloXzqunfw3Lb7q0+yZHBpZoEp3JeRQbpRkYjWAmZeHep9seTDgpguvr6NGSS9iwYy4qoHko2oTB68\\\\\\\\\\\\\\\/W39aI2+MJ9HtYWaRrOPm\\\\\\\\\\\\\\\/1p6hsupH0uTHDNvXzmQyfykPL1UAY3VpvRctFDVfL1jvEc5Hx8Tz0OgKQ7kbT9tyAtSwec2vktuDS6StKcZ\\\\\\\\\\\\\\\/fFFWlAfuBzbf\\\\\\\\\\\\\\\/jfNNgLXMCWpHC47jI0s+QjIZKHhwT9Mz2F50creLHd176cIcpgZuoxwuaFo8dJmuxeW1qEa9llsZYFt9ggeuzoCWlMBzVYf5+skOS910kdDIumFzLwVcwyyO0yXWvHIpQOGZBcooJgy3tO+p2bn+Xhcm1k\\\\\\\\\\\\\\\/ozPU59+raEKDKTa1RzOGxZ77AKCO\\\\\\\\\\\\\\\/0x1Xa5kCWRbvy5C3UPU8\\\\\\\\\\\\\\\/sGanF9zwjbHE3esWIJSMYjTAnblNbS62fyJVNRqR0y1\\\\\\\\\\\\\\\/m1R3TnYz7wECLAVP8HHTF0sT7udBZMGdlCfn+71533maG4aIPNe5CDHobWySBBXqClODZ+MGIhvODhFKitvA6QpOgIJ7XSK2xPT2Vni4fEnX\\\\\\\\\\\\\\\/FJCTNsPei5YSkGuL6yiBjIkLqps0IwfaGXdIFtNXnszYEYr\\\\\\\\\\\\\\\/nhRAcohL5WH5dU6VlO6DQGVndqNn+eP8J5JHLv7P2b6OHLYRLGVaLDsi4POWMzVD9fsaVu55UAS6pPyyol9kQYOhZulYALDz9+izxLu601Dkf\\\\\\\\\\\\\\\/MlJayx8Mn8x940WKgPxhxWyer1J+c0yB73TZE+WYYA4TKAswqd+2V11vDV1HuqTVaCwQS8VBSTtV7LAxnDRkFwG92dZrdOKJfsE=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022I+fUApXsAFj3TS3s4kVuag==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002208e02314781cf95e2e22a81557544586e4b44cae0bc6cda5e02c963e4729f676\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1493.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1493.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1339\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1339\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1339\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}