{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u00221H8ALYEpsyShBQ3NkQd8wI9Xvykd64EvA9s57HkLAR8tdop3JWQUhn6UxtqEDa4GhalLrVvdx\\\\\\\\\\\\\\\/OqIpsWGYrEhuj3oCzkNL9Ov3UwvUcAUQJohjc4v4ZLD4HSxKjPca3YUaoTr9GRT6FD3zv22RTA\\\\\\\\\\\\\\\/TdndYAR9HcFUco2m4aqwtnwEjglbrGE0X50aAfL8Xbt\\\\\\\\\\\\\\\/EGN1LRnEAfMcc+tS+\\\\\\\\\\\\\\\/T2u6bZJoL3NHLBKJCa5ucy7sPcrOEtLOVkuXQ6LRrxZBhjVWG1KSfu2pNhXMmAQwdCuuVQYdSSu8s4RDAKxOL80ZWy4F+JsZXSeHORQB6h0DUz0ybdOWMe14LzSMizJtg3WDN5ibk1Zoo3l9HR71i74Gv5zu9FiQ3n\\\\\\\\\\\\\\\/WGWrtxZ+f7Kb9dmUBxdqlvJvYRpl1CheGuZqKtgOQ\\\\\\\\\\\\\\\/ymhBD4Ex6V7cDxW+rl6iS7JRX9h1pd3gj8K0eb4mREClv+7hMOHRflK294C2L6qeP9ARV0tpFu3av9erZjT1eCSBL7CBdJtFjvcmxYkOlqCk4\\\\\\\\\\\\\\\/spKlLhiomVp5EmdTrfGvWib7CseMoUAL\\\\\\\\\\\\\\\/ZQpYFitQcCNA5pAJx3cwz4twhhxz2+BEuc9a6jWUWThq2TyFDc22IjCI6SaKBSlkkynGkZq2KdjEh6+uE2t9KukrUmcgVWGG+OOfPce8QwblCgxmbGcxakxmNvQgVHveZFovbiUEW4kmH5eD\\\\\\\\\\\\\\\/ImR9u3dRwQveXgM4eqoWmgVZQDwwUiW1AIfXB3LEGi5OH4AJHDHnwk7DD5MCLZBjje0TSczoCIscW1Xo\\\\\\\\\\\\\\\/gXTiSEsLYNdRZ5al1fbzOhQVlBDzqm\\\\\\\\\\\\\\\/w52sDlZtBp9usUAuXHDHl7BDz4QwvXJAUEqxIBbpueKyrjAgxsY7C1VYrNInRkkB7wh93Ef+jTjMzgJJpNn3aI+GfUMnChSOeY3hG3VgEQsDGDmmYtJWGg4V2z\\\\\\\\\\\\\\\/xw402XWTJO7u4TJG8rte4QSH3lyLjIeacT5tSJZYjle7AluNZxgr7fUfxL\\\\\\\\\\\\\\\/aFPDEmgv+MaHfLhysRaBeqAPVz4GA0KnBySXp4VI+ob3IHtaBeaBQ3WoWK+6IDqSsTJ8x4ZYa6xzkep74W3ie9sk4xGbUJySPPlR7+ogriTWx9sP66bvtDNmU0srsXYxaZJIDdjP+nmjdwMBVhlOEAKwCvnBIfySuzBha0DTQRoTOUqHGo5dYDi8m71lUjeT+rMZqAUgg2BW1UVVNKr0BGan\\\\\\\\\\\\\\\/z8cnN9\\\\\\\\\\\\\\\/TkVHKf3SNUEbPe2eXCB6h30D9BkGK1Fg4mJs8T+xLjYuo07+CGL\\\\\\\\\\\\\\\/Q2s7U8QoLefRWQC2axzGsbcAiVulSYOQ0k1yOgFbR5nEn4Br8iJ7v5BhTFRkKa2g8xyhJWCzXGt3LCPZhJszZ7xhL\\\\\\\\\\\\\\\/erWfu0VdD8qXF7ARVvmJytvDGzevfyhr5LjfPEVPLpRuosdp9Z8f0gGcZkyjpQNaO\\\\\\\\\\\\\\\/mT2aWOG14VNKd5mZY8KpNoT2J0JQS5P7AnFTUohIxXccHf+iFiIgz4hmi53f0x7sj2S5X1J\\\\\\\\\\\\\\\/08L8FJV2Wi0ASZj6w4yQLIs7Y2gDp9k+Gcc0qqLbpPGLcx0lHky351Fx6AV1SH4iuON8Hu4vHtA4t\\\\\\\\\\\\\\\/jA\\\\\\\\\\\\\\\/QFJLo9o8X+FYOSt9ighFmW7LOWwIr2H8SeToGKDAXco\\\\\\\\\\\\\\\/9Miw9B7jDNRVjS10IixDnNGiBshaL+6FaUF+WU7zU38L86NGL660IArYYEuIqgQpAV6JPiSA1O3siQ6gM+n5OFdp8KbcLUmCUxo\\\\\\\\\\\\\\\/eFK8oIS+Z8lxcHfsuPcRo6cB9IqGv58bhbHknIl+ev9YNRTeTfMjlZBgC+8BmpZPtPnLr\\\\\\\\\\\\\\\/TuYF1Qj0y6KqL+FX3Rl1AeOYIe0fpNZduzr62PdGwo4qZyCvwqls7DvIFjI8nta5MSKFoZdz2lZPnMcEolpuQkjdpo1fBkSnu3IY4BkelvcpWBWe6rMQv9F+JKba3yPPmXCsmerP+dmMkjV7uQsnLDljT0UMQeLlSj2BdwOk5JR3PDJldpBp1o8I0N0a8gPVbYlFYWNBb\\\\\\\\\\\\\\\/vkFXo1nj1Tv+4yVw3dLvCNIlwbKsWRee5SI8dRp+Jly968OiMti+7zHd9Wt2lzuBp2A9LD\\\\\\\\\\\\\\\/jMFYp2IXN0SO1nDCm8vUNH0\\\\\\\\\\\\\\\/xJkEVOFO9VEwPZyhXLMa4mHLUwfFXCAIy+lOVprPHhF0Pj1YWvWOxjKgIT5uYcIxfNOFiDhgg5twCONJI7mxjrOb24B\\\\\\\\\\\\\\\/yb1mA+vFap8MpvTW4nFMSPmly1FhwdlV+waMPgJk1jr+haLpVQ5n0MhfZyXkesrHLOf9tqDwR2K6yz5CfmnmaazJvzMDGvCH41RIBFALgjhR3NazSUj+nGdXbTOXLc4bV3VQ29FGvcVrCHbglGbHQobpDe4j7ndyiKg8aOFbAss4AjPeDxgqg8PSWJdOAZQgiscgom3qSpiXXs\\\\\\\\\\\\\\\/zbLpgic5EWbnwGeSiUlTniAp5glkmdqQyZqgz23NW5fS8m89wr9iQUfBDeFIMBBQgMZhe32EgiWcxVCxjzfRHB7p\\\\\\\\\\\\\\\/PS5doUJAL\\\\\\\\\\\\\\\/uVAvvCsinwQNRodHF2hWIdPjCCh6lqao\\\\\\\\\\\\\\\/EW5cE\\\\\\\\\\\\\\\/jz87hc3zcj20AebrQKO5hWknDY+EHunKlLDgZdpMFeNTE2+mZyDkbEYur+2D+0Q9I1EOxBRU=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022EUm0fz+wC9LJzHepw5BUHw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022a375356d040ef57dd256f6d8ea2e335ad5b6403c8e021f016f5b88e2bb2b7da3\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A966.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A966.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0867\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0867\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0867\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}