{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022nOVwmMBHq8awgK6cSau6bhY6WEE1d+j7TGyfWgoL0t8DxqDQwJ8XOb7WeUs32F94PWueKgTMNVynwjXQxJ2SwTWQPEx\\\\\\\\\\\\\\\/Vg8I62aHJPDVidpU\\\\\\\\\\\\\\\/yXtT0Sa+kpVEN5xqGo6vja3EQy+vciQq7rw9o2lHWStFNGhIoLSGti5ItiZUnDd88CplJP7ZA7kOmKLoghmlSdm2Kgd7iCmkT\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/F28t++2E+UdOrGp2rCRl2q9krXCd5PM77AP\\\\\\\\\\\\\\\/BhW3JOFWtoOrROmaxwfKplWXbvQQxOGgRn1yt25v+JYAxlz4a7yHT5eQ7oido5YYoc1Oxnq5CylDTBFGz7YzeTgR5w2VdMnQvm4AnzL7HdsLl3GEygSOLRR48jjJe+xm8Q6djQUQsUxBi9BxbQ6Beg3EJHcdJ1BDCqSAql7sAOkcbqUwxbqKfxo2F5Nd59VJKDfO8yKhTutiKhdzcnQY7ivIBhJ2DKfznoS5O9C8PMRXYlOxs4dscYBdiqUmeEXKoKymVR\\\\\\\\\\\\\\\/xsBhjZLzZz38tysZP3HCYXnTBxdGx9SZkExaCh5UHZUHQ6d9LdKL3kYXroLun0FHe8Bn0SdBcvK6J1Wrvp\\\\\\\\\\\\\\\/YNLpujrlWHv1mIEOWcv+QqPOIHQ2g2D\\\\\\\\\\\\\\\/gWMnKtimrWKFPvNyE8SYZ\\\\\\\\\\\\\\\/J3YK\\\\\\\\\\\\\\\/hQ8nyuHNyXcpy6zdSgq1MolFldd+nErQKW5lRDAoubm9n6ba9Lu1VpyPOn\\\\\\\\\\\\\\\/JEzXatMzYY1eYurq0FW5\\\\\\\\\\\\\\\/0uObJKXXNU4XcV86Quh1cP7+raa4Kb0OLWQbHwUOZ+I3cGk7XdfNxZoS9nVfDAa2sgQGRMT4cn7HBO3PuEFfFzdw+lAV2OKMB9vJnRhV4q6tuzFGdi1xjnncY2k90ToZm5Zkzim3wFkWqQrGClZalVg0sQsm6H8gPpEcPYMMurGdPAxQqb\\\\\\\\\\\\\\\/3wTuLp50v6MP2PqCmexLqLNqunxfLcrMbz5gaZyoiZkVIlXIop3vfjhEi\\\\\\\\\\\\\\\/chM6bvDuS+avFlr90VGe6Y90390JDAdZmSGwgKpPxaRG4hZPkJNAyP8uJW3sahHiq\\\\\\\\\\\\\\\/UCcQ6Q4oujlUyfA7uDRbxK5bWOgojcVv3L\\\\\\\\\\\\\\\/5LRtQL\\\\\\\\\\\\\\\/ecvK5aMnDTrl47o+s+XULQorzPZnmmH8QQhyAqxXy0KXjswWd2UGkQ11nDlzMv6A5wV3NYsFZai+ty014+6ys6GYeV8uglvSesh0cVsrUbI5gPLOO1NeBsyKGTm\\\\\\\\\\\\\\\/XCLyEIdvrrAaC3bAbHZocGgu\\\\\\\\\\\\\\\/X1JuxiOsBexGkGD0ShU6cmnyp1CxTBriFfRZ7sJ2G2E8SSj\\\\\\\\\\\\\\\/7k8p\\\\\\\\\\\\\\\/Fo6KT6p\\\\\\\\\\\\\\\/BOwZGPSBv9EoJeZnmX75tSIACD23NFfSFEcnYT6lZQUJggYPDiJ7XlNKWm7zqrzdNvkaezDgR6kXeedxweszeEs4+IPAlOllC7VJUXRVdkb0xtxsmgDv+l0jdy7kUszZINx4q2rKm4nn3uFjkiIkdX3ors0aWQ2XoDWfJVAICPZ+v\\\\\\\\\\\\\\\/0XlaGAh02mq4AfiAz6iX3tDgvR\\\\\\\\\\\\\\\/GAtZ4HlW14\\\\\\\\\\\\\\\/KqcdpMwPk+ablrEsjXUDCuKqhntuY\\\\\\\\\\\\\\\/pWgMH5H70L3JX8Aji39EGsXDSW8MZOc5ligdnCu5akFl5gRXSjc2tNMRo008MoY3Jgt1z+dY9j7ivVF8RA7R+n2nKblZzdDKazcbX0hfsgVWpLm8dXssAAAaPtDIQtszLGPUSSv98jcYLcGWo2s04j\\\\\\\\\\\\\\\/c+wEnVYajuNT9K+EdVbz0MhCI\\\\\\\\\\\\\\\/YyDgedDkkUlnDSN7imWL2b8XmdquS+iavp\\\\\\\\\\\\\\\/lRiaD+XhA2norBIyBD4rKRRlqp8PRpNyUGo96n9RIPcNPyICbyX\\\\\\\\\\\\\\\/jkOSrcrSZJ25qSvC72vpeQfGZHmjKpzACGyOo\\\\\\\\\\\\\\\/9FrpjEuDYxnB1REmB9qXS83\\\\\\\\\\\\\\\/7M69KzvDMbZvycSZyEHIt9\\\\\\\\\\\\\\\/8vOCQTa5PaPabyc57SFuaCC3SNGU3iAwFOPfDEjR+kvoAh2cWvGUewpA5o4RiNCXEpVaBlu1dQrVn6sxU2+eBx4SyZERUu6zWBTBXbv5YMMuNleAtLw6t7CSlns9RUZ3VCj+n1FPF3dRFqi7\\\\\\\\\\\\\\\/HXItNF\\\\\\\\\\\\\\\/Fq6VNdK5JMYFEi1YCfpaWjwBclwXwS4xiW04kgzMG5HKjnYziqI2EeBRJlYAnypZghoy5\\\\\\\\\\\\\\\/Jg3KjZ3yahC7bTpAvpvtfIImztm3+PiMO5ZT+Yab+WfNcwgpzhg8AscQSDpZcKzi\\\\\\\\\\\\\\\/IOYzFlrtH00xtIu2fMPf\\\\\\\\\\\\\\\/X9DnPqyQXRsNlp+qiYcrM\\\\\\\\\\\\\\\/8BUgab9ZNx2+zdPyLpHyMvG61+dhxrzDhqsUu1Hwqjl0tSYg1Kavm7pBhvrWyuCvNts2vAn57KFdhdWcL29zhxxZB8SqpP2IPQIKjBZsSIaeUeLE7r1WWOuK0rBzY9RhInGu5tz08o7iEqljyW7OcBg2byQ6JJXxXCkVjrWiDfv2ZzuGmzsTYOcxVByvP8kPbdtU4f4hXXmIA3mhUEOuOmZUkKVRLKXLJ7R3WV0bw5TcBZn52WUgllnSnVtogMMFio5S+cvqyzjYWi1wZ+EBpNP0DZS05va40JOm8YYOe7aj1RdTW3\\\\\\\\\\\\\\\/NViZ3T0khNPCn90yX3ILLQzdartDjyvJeYbQigY8gdLAG4Bbk7K3DmemU6uLry7FHzKizurIzhhi6DSNYK2CUOlhkjw=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022TH66p6xBnmD2nJYsWOxH3Q==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022ddf5d2f93700a1f2430e17a82351c02d3752df53cae4cf0fafe5fa3a4b81199a\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A401.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A401.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0352\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0352\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0352\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}