{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022w5ehsHLZ0deo2ouVhEyQKStIVorieTJG5q5kT\\\\\\\\\\\\\\\/MzdS+ipslCEVn3EGuz8uA5\\\\\\\\\\\\\\\/37\\\\\\\\\\\\\\\/mms0n025AJIv8fKlS79IdOIf2Wwv120mzYbDoHAKKTR\\\\\\\\\\\\\\\/sUo+JT12R2qBoKr82HtjQzKAuk9D7L2lWVMQkVbB0CPkxBOqkqGdTaIxMdEEU7CSfNmGzsKQu2pszSq5srXebMZafuryqDvNy\\\\\\\\\\\\\\\/mCUeX\\\\\\\\\\\\\\\/cRM3fTrr6dRYBT6JNsghu3HwQ8KeiCkTJZDpgijnUmIwJHQGt49FKiMqOP81yWj4x4IEvath\\\\\\\\\\\\\\\/cUB2+1teMR8qr183BaoiywA\\\\\\\\\\\\\\\/6UVFhLcEftKdo9UtG4bAjbS1JlHkNfteFHGIhgUNBZt5uzpxFkXCJD1sXdn\\\\\\\\\\\\\\\/S9gWUZ91kbfKDWYRIAsZVsoXgcviAiAVfoSKEyX7u\\\\\\\\\\\\\\\/R+dJJ3K8JezyKtqTsVLFrOaC4jf2LOiw8MbBawbirGO+yMgmfBQGc7Pzymm2qgkC+FAIsKi56HC2mH9dXJ4ZnPygpTMIXp7YHGb9tLEk2CU+2vl3E0e\\\\\\\\\\\\\\\/5RE8TgBlqLHFvLbzqwFKSBF6w6Z77dtvDe64P3wk7DlszPi96250KfVNsYDc2O2LmtHKBcW2BgsubLnx0SbMFT1n4ZJA3ehiwe0bjAv7WLHZiSKv2pqurCfjxyUMbepmu4CbayaTxuaogWXHggaHCpSxXtVFG\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/4pVeOdAs2riT43F6+CgLvWFHzWeP3ntlaV5YmJrlwiCLcBykItjI62Gaw57JM2J8u6fLRismKfZKRgfL4bk3Q5iNWPUBKFQSKA9DzPFxIMEq22TZnVJ6eWN4lUgOZNGRS98gAXfIO7LVCkkxoMzt0b3s4OFU7ERKoi4QD53v5dI5E0s70hdAbtFMqS1aMHH5SxK8AP\\\\\\\\\\\\\\\/ZXZ8Gvszb143V4my1b+bZvL2hIVm08qGjxzOcfdtnHXq4cHQ3i\\\\\\\\\\\\\\\/gBNnpDEgxWnJYuWsH9cMKh2YrUdpxZCmHDAZf3d4qFiMnnETG9MGmqGjiNHzBmDjNhqFMzASDHyITGN9DAJQj5HVd\\\\\\\\\\\\\\\/QE5M4oZVz29ucAVa5VWmI3+13+uu1620mCmuMd1DAI6VqZPWCED1nunlxR5UV1W2YX1QHzN8WWDBA0b4Enwjn3QgDqQFNEKzhga3VL3OO2F4gALuwENefisV58v8nawk604yaOx7\\\\\\\\\\\\\\\/2VDOi4O2uop+r05\\\\\\\\\\\\\\\/XrbDN9AeMKtrSyXTOui007fPrjw+D1Qtyb9sUhC2\\\\\\\\\\\\\\\/FJ\\\\\\\\\\\\\\\/BvS72bjjYUlN6pncZ5MR0ppRU0Ox58Fy0YTZukhn0guW7Bnf1wJK0Ox5Qt7bseeWfQASTrWqbNVTHw9qa5oBrRiKfXcVoRUIm9atUxxo0alJXsU1uqDdAte9ZXkDedPJSdjj2YvdVnYUuvQBPJNYAj4eKPgByAjN6DbnYkrI5tPqoiEzMWGSirona5CwzX39IVehC295kwmtiuT0ONq\\\\\\\\\\\\\\\/PT+HU6OobLS8JOknz3\\\\\\\\\\\\\\\/PgDT+Cvx03LznaPo57iyb9eVvmBwKlGhk9prOIInpug5LuPFRTNJOkMzeaCfn0f3LLza4NzD1LRIqYrZVFhKxmNi1yOxNaGuNjXqawuh0M1AnWuuJPK2NSWo9UPHdicx+7YBjfzkx73G7Voj+xy572qHCdtIFrjhD7MiTH+M7FDyvA\\\\\\\\\\\\\\\/RQuTTBa+mtdzFf2Zckn+4fx6VdaYO7RIuXZYibVwzmQ4Zgmcza+71kOXIPHefA9lACQQCE5XWLPBKhnKfHSs+shbKDAYrSLKAcGBq47ZljUofIdUNdcSXbJ8luiUyGRrEkA1RqdlAAq2UXNo0rjq3+Y9lTSYKqh2uVu6AbkbwhG+3II0Q7apFSVMk6t8LgHxnHMOmFKZQDjiVFcOhi2eScFdcx4\\\\\\\\\\\\\\\/IzpcW4p3+wP4I0MxwvN3gsjxflmrR8pYqH5COkI9u8roiHv7Y8WS2te+WdtRfghP7ZtGz79uGeVkxvK2lnsesspMN5T4doSlVwBAOqQM+oQRANR1uRj4IKsnOu8CMVOvpnXsMvRLUDMgulkYK2g3SQiUUavFEtPKiZaO18Is6rWM+E+jTYWRXqvymUBUWkIfWcRFa+DOIEjqHQBFFFkdEPAQuqv9u6FnJIgVQ9BvFhgAv91Bndr6tubeT6FZBa+rPx2eQ6I5gez10n9Qk9q3tqNRCiKHaCcWuZcTXv3Gd28x61BZaPFdUCTWkX3P4Lb9VNJPyXLrLAbM0VFnOTttMreTC3GgoIJKblM14E6Eg4QwEVLsrMK96rArDUS69To3GlTEId76\\\\\\\\\\\\\\\/m2qTXtmJAvZJe3\\\\\\\\\\\\\\\/bMQRyKEs5JcsUirzzH9jzQ3FDMqaXqiFvkCKDSm21B5CEFSyC3fw0isDzSNbvbo1pQdLRMvLNNAMgOz60bKSvl\\\\\\\\\\\\\\\/q28+i9tocGgrzOGGMbTyl6sjxRRU80H2mdhv5yhwR\\\\\\\\\\\\\\\/bEY\\\\\\\\\\\\\\\/NpNv\\\\\\\\\\\\\\\/2lISNGjzj4I6wS+qbVmCRvNGG66V5F5CAvd0i311XS3ITDxA8mzCG8z2+TVBi\\\\\\\\\\\\\\\/5yP1sxsnY1ijbxH3ITo+lU52599dddnyZULi1iMDWo2B8rlii\\\\\\\\\\\\\\\/8\\\\\\\\\\\\\\\/cqO0PCH58\\\\\\\\\\\\\\\/gxDUtfBBFRjfZlhPzFQqXVtD8dfmI77ecUe5eHTySQuG3X97dhfVwR6zyYyl3qPLxDaNWzoFIGak5Gbnqj10=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022xq5jGyPgyZpEIYtHvxw9nA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022d7f3b01e74c92f9406779792f5976c7d6b842b085a6fa9a597af9c60041f4f8a\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1282.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1282.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1163\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1163\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1163\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}