{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022isw3GA5dmaprzOn+VhNjWjgh5YhDlzFPTNB7bpQqr9d2mh+c5o5k4hNcC1GukSgwrf3Ery5enXm5p7WUjX4RWOiXDclT0OuAfBDD6XwN+ZUGFQEHikhadRlcBEOkC4zx4NVTL7iEdxaQPH\\\\\\\\\\\\\\\/ani6Go3byqP\\\\\\\\\\\\\\\/9EeO1SxMITCNeq2t0znATgwJPmSosemuixd8z6PXFSiDyPK1nTff1DqpBjKlOtsfVlhYRVwq06ChgyW3IJ1FoctOq7wdvYYFa+ugb6Ikwg5DI6wDMaaODyxMD2tEt8QlOK+J2AAAb0Ox8QnNj2i4Wn\\\\\\\\\\\\\\\/4wrXBuM\\\\\\\\\\\\\\\/sYA\\\\\\\\\\\\\\\/UdJ7eHyqGK3gGVMLXiFFfS+B9PRS\\\\\\\\\\\\\\\/bXl8ubNM6d\\\\\\\\\\\\\\\/prTfCgwzobDQSZK1Q23TXe4A6wJxbbnfIx9oDg1cP00H8o+2QBhNmGKgS+VPzNYX\\\\\\\\\\\\\\\/BYp5LL6y+c37UnC5zWXHTUwDuUWcOwBue3mOYtgRHpDXnHQOvyuuVU1jJQLMjlDye6NwufnLNHikn3fNSPnrDcOAL8sXJH4kyRtnaTyQfyubGIicbZ6aOvH9ZBkUDVD7ag3FfWBqJawmkKKXIe\\\\\\\\\\\\\\\/GK\\\\\\\\\\\\\\\/Z1BWZcwgOaaDtzeJWU0oZMiVUgu6gfFWMnt1sO7kZqxw8ZhhhUwKtgQvCwbmu7EQro7v3R3BrFgRCXtcz4SQyWqiNPnmZyQOYcBN0W7sG\\\\\\\\\\\\\\\/X3UDn9T6JTQQbNxmezD9bABDqYOZSRJTcpjuPLaIbuRlZUAlACxAYlvrFN5ZsVN4dt6D967Z+xvMaOSKi3CtlH6EdvVjsvjgQWrmGAHPiE6RGEt0BnVTo9\\\\\\\\\\\\\\\/ynEvGsIaNfXEfU7lGN74psKSb22rvzzSBDF\\\\\\\\\\\\\\\/Z89bnRw+tlxQes2lBS5gaiRBH\\\\\\\\\\\\\\\/OUiDDxMP156CIg+ddDKMk\\\\\\\\\\\\\\\/p1Sh+WvigjhO0ehe70GanNZ2NQXgFffEtqTn4OXxFQNmwqU0tMPOYljiyBK9mII79cD\\\\\\\\\\\\\\\/bUwUuO8N50bJ7TkFSkb2Y2LV17mQAtTb0eECEPPOyhna7iVbWPjdT3zMF3UvVcf\\\\\\\\\\\\\\\/DNQm3H\\\\\\\\\\\\\\\/f5Ibf+HQcHYIV6gBCXahTrPgWqn3xlK6GU587VlGkfWQigUDwIVhsULW8dVTMkZO2icRr4LA4CCr7UHCYVTIu1V0f71DQnmuGKx+adtzA9LFodYjnDHzcZZZ8oYKfkvXIfE\\\\\\\\\\\\\\\/mJXbvM5+h5tGMB2zLfM7FlsCHE4RPQTyHO+Wh9yudrOzgK4EPO4FmOO7nStDh29JvnO3EPGmlUqSuKS8Hqre6fVpP7SSbwhzDyAQXYWgSaFZNp2gcgMnRH3Q6wRG8GmvoB0YTbcf2\\\\\\\\\\\\\\\/MA\\\\\\\\\\\\\\\/Hwq+aPE3EZsiPVCG3\\\\\\\\\\\\\\\/Z5dmpFSqY6zEa7AHfGF6t+wOhOyzvdtQ0AQVqyUHtabpnU0ibO1qLcTNQWS5k875iYQfEvtXFT75RzKHH8tEPn6TGOhl8fPdBEBb0qrsuxQ5gehMRF\\\\\\\\\\\\\\\/1vryskHPCuaimLcHYqNDvuTjiPVBdHKCUUGNxxOxsEYarqhNAwIpYmXd0dVSfK1xgL9CV3CkktA1j0usTJxUrpiIX6uqLjlw2VuTTpens3qw\\\\\\\\\\\\\\\/bXtimarA\\\\\\\\\\\\\\\/9XHB23buYCWouHJ+tiJevShEASPUYPSdIw4OWVYpao2DHEbYKwzc3KI4FgEqlWarZdq7UZO865FDBs5jwOFpWjd55Yux\\\\\\\\\\\\\\\/87P0sJ\\\\\\\\\\\\\\\/ccsyVCEWj+5vSVvWde9HU5BccRI8ZSEHkaU4qo63VIeIx9lDmxA7BxvL6qR3JyUYEY7y80l7+kLZEIn8Ehmp4mZ57rGYHGT9NkCEUEIdZGz6LMhHUOOmiZs1H0S4S9i2dZoHoh+Wu+SHElbQAzCNuYXLZwKlDd3\\\\\\\\\\\\\\\/y3h8jiDx6uS1G8hJjMAW+Wg4kNryxd8Rpmbnvnx1hAkpLsjs6uARNczvfPhpg\\\\\\\\\\\\\\\/pPkcjpBZDAYpsdMjvCBWIPKzDBFNT0wC+fjbZaUPdOuRQkWMpJLApKWB\\\\\\\\\\\\\\\/OXr\\\\\\\\\\\\\\\/RGW6jTlxPKQTQhyqIC9obhpIFz9CuFRCFwjX9B6JskvLo9VF1t\\\\\\\\\\\\\\\/zPtWWoCNCVQaCQnEI69IY2Bkog7kmUS1xRvYbXLoiQ6Xbcb1YNofEugBt6QLq2K97dBA0zy5eBkAH4XeDIilgaZwUu85+yYdNEZZqjHXHfujc9OVomT2RNof91FhahP7EPGJ1jAhQ3GlIdDmjmFZANSfjGDJ5XQS3a9z7t1cDfoPV7sprG70LvnrPuASgbs3LBzL2UkA4OHnbQjZ02YSZwzBUjKzoWGB73qw3+bj842zmcCkaYr3Lp0V48OyDuBKI6HImr\\\\\\\\\\\\\\\/mA29KNQc2YMLTVGTKuEM6N02tpuotzW7IKzq87G9wjdOK63vQ2Ddmd2+qN3jlFHZ9O8v2qNZ6LiQYqaWGSazMB1v3XERHLr3w1tIrOYp2a7lTR1OTyC+koq5ccF3DzpCUDz0XGm+oEg4NLkRhGxXZmjtC3KJJlGxHC40\\\\\\\\\\\\\\\/6eE4p+8JRNKQDftu7SlOak1Jl1L7chwjoyOuwOgTFerFfuJHyWSAknBoZT+a9B2seNcT7ulY2tvz5dsfvBwkQGOEiUamejvCGwaN4\\\\\\\\\\\\\\\/Im9n4vIYTifS6548LbRWeILw\\\\\\\\\\\\\\\/zh4AOpun4Icdtx9E0oblixEfsXMW5bi91KuiebPh2vweDvDmS\\\\\\\\\\\\\\\/BMJLuFxOrUPCj1vXyG4=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022VpYkZJ2fCBEZSJDKIK+9og==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002201d1dd467475fd14bf376e0840ba1e7b97f94e0d288680e370931f5e8d043579\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A153.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A153.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0133\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0133\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0133\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}