{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022+aRc6HIwIXEzHumxw8VdcnpmrPez8h92D5Cv1xG4nFz53d5QSmvbQFrp7\\\\\\\\\\\\\\\/S1u6N+\\\\\\\\\\\\\\\/DOv27AsEd03jh\\\\\\\\\\\\\\\/HTczBC5Q5VqkL9kUyBNsI+SlMCtRmsa\\\\\\\\\\\\\\\/IXEbtJPzLQU0kSPRyyGBheyzebUFn88oRhgCVC+qY3SHD1sDeOg\\\\\\\\\\\\\\\/rKVx6ODYhDjuGhzrvXPsYN1FeDftdLrUOKpjsUkoAfP\\\\\\\\\\\\\\\/8N9hZjq1rFy+ud7V6Am+oxDS0OcQEW8SQ395+zZb\\\\\\\\\\\\\\\/ymP+FQpYtPoaHBr7fu1rr0x74uLU0g7OenCXAUB0O+ovsHL2xHXQ3qin4VK5s8rCUf8B5FJSOFd6ACHJh9dBTDdQbjgrjJX1I6\\\\\\\\\\\\\\\/w6om3+eUZoIukuHZHeZCO0npDwlM9nI\\\\\\\\\\\\\\\/x9zcPwuqElk4eHj1a91GGFd1FxPG1VuAjCg7KEGd9A1dZp7P48Wo+4GZcRCP3RvpZ9K8TZ\\\\\\\\\\\\\\\/W+WVx3II\\\\\\\\\\\\\\\/jSL9wNa88SdAeJYaQ5qjjlOZe2W7GFS4UJFLqmL6gyI\\\\\\\\\\\\\\\/j+hClfadFftoopFBPJvFE\\\\\\\\\\\\\\\/lQ35MpXkW4yGzCeWXgqCC0sqnjwmIR+WQJUZVpZBEMqVcPHpvjDR73BRz2yuDoIXDDFDpMMY8+3zKtD1SrbNyOLOZTtPR\\\\\\\\\\\\\\\/O5aLlyt1WIJv7+HiD3vMDsdGp6st07KlhqXJTKgUVM0X7oPGACkO+vKWzW6VdGYijvAYXh9EJFPRbzabA2LI5Y9ut+aSh3eq2tYkLYOJoftYwof\\\\\\\\\\\\\\\/IeI9mNtXvXAC4P6EbqYx+X5aB92HSmfw16acNZ72l3hO9NioszMh6wNiEoxz\\\\\\\\\\\\\\\/DVoyr1WF9fgThKGvcVK2TgFIUKxG8PUjNiRIkrmlldxuIPrH8cDQY6YYU4u4zpFZ\\\\\\\\\\\\\\\/PUFvAwdpuzYMgagBeiKPI4uTfBkrNvInVLfF6s92oHyJl8AN4JqidsqL86XDqiiwAtkjUZtBPM6c0z+F02VqgbU0oeYEfmezpF3iXpICIcE2bwaid7+KVP22RIjvaTsvvBldoNFNDMpTdUQpoPLw2\\\\\\\\\\\\\\\/ZEXAu4jfMhtXkcrai7pOi30VaDghdP+KWPw0e3h2OzmK7Ojz4YypJubWR0mnd7Ey9Rp8zGhFkrphPYnnfRVSvJGA5tVgEBVL6ChKAYgPrrvC62RVbinDJxk+sO98364jV\\\\\\\\\\\\\\\/ohJwpiYoEBBP1su\\\\\\\\\\\\\\\/lmDT\\\\\\\\\\\\\\\/G8XaW6WcFqwdLJBXhZz4mFkpHaXFIgysbe\\\\\\\\\\\\\\\/pWqGT8JHCxKrKoMNfkAlgTBb2Agmi6rZTzmdrQko3NkUqnrJntQTshALN7VhdXiKRU1pfsOF8EwIllmIh4wPSQtYbhaDeu1irBYPic9jUXRIOXYJDc4lEOTAo2r9M0Rpg9KlPqCOvy4Kf0RJ0hL3QNGUpZpHQApmtNRpxJZn6ldmZcGIBsRPRPBEzEFmcjN3cQSlYM1EgS0Iw5FS9+OHT+RH+7PLJCEnDJ\\\\\\\\\\\\\\\/FnzkgYTm2liwB3FSTWZQPLmXLsGoJJS03pjGKTEQA33WEGRSW8Md2AfLghTSPRcM+\\\\\\\\\\\\\\\/G1syEsF8JLppvihcqeH9f9fwXKwjB5pMRv9Q205d5Tms70rm8zR+3iTQe4uzlTDXeTJQVk35NWHAAPV6LwlNk7zlXV3ju4cTlDpokwpTaK+Gm1gYt+q4WTh9tDcsHEgGCRCbsUMd8bQU+nCSDesCFXdevAb397\\\\\\\\\\\\\\\/4wsam6PPGm61AEytxvsdikxCQRlBwwOVAQ2EwqxDFe5gIH53vSJfO1kesv7NlEcRkieNy3PQGbqyXccQFYAxx19S04\\\\\\\\\\\\\\\/r\\\\\\\\\\\\\\\/pkavuE7gLSJbtSwUkUIcuV0R2rPFbUsxfNhjKWUDeN04m\\\\\\\\\\\\\\\/F7pShJL5I397DIO2hmWZ789BuXwIpwvkBAYCPyIAMT3L88sJKvd46OIHdCMhAp9J4\\\\\\\\\\\\\\\/RyhO3rEygbu0Y5gwfbji08Ah7XD+Xt2Sxfncen6yZz1YtP5EZEkBBVEIYKCam2dmJ4ee4V\\\\\\\\\\\\\\\/zeszavRitwRLIvchiL3l+8YlYFb9wwwZ4OxSxONEISqIYCTcY2q5twCeHku9Lam+s06\\\\\\\\\\\\\\\/5r7jvkPmb5NKlgUomzBen+SCxXICX4OEGBZhbBNB5f4Ewugp7v5AHJvRk4tzEMR96FdBgbFt\\\\\\\\\\\\\\\/uZ4GvTaYfo1NHeKY7LEmG3m70rf4GCpx6JRZ\\\\\\\\\\\\\\\/fK1WU6jhLWqffiE73n7PVmDFD21q2CxWxaB6fZk1DKTRbumuUJ6c2+6llqajZHrTmKak6eC6iZ71IMVRYRtboE9J3dgZgWKf44iL4sybW1AzyzMqKDb+oVv+4zWbKEEj\\\\\\\\\\\\\\\/30VaPuNH5bMh7Lj0Kd9wxCFL9bM4huD0XkDdK9DR7ldFR0UAzPt6gzhcQMykSicpO+SJUeEXUQykVi6oq8tkLm3wx2NtJH4FDua781rYt\\\\\\\\\\\\\\\/Jd59VRJu312QzeD7teptVtqJ10rBTP+4kUodLe7ZS4fRjR6GsqZdUDR7GCu\\\\\\\\\\\\\\\/dfoo1YPtyK1rG4pHjaVn51Dvl7w1u5ATZwgpXEVnC8ZaXSXFbQu447WRfjgOi93TJw+bNNY+GKNV60aGiHoH4cabIjtYApszAxGcgdPoNwcwvSDcXkpjgGvGIG+4vBZFxjMjbjXquVWlV\\\\\\\\\\\\\\\/z0oIWGlfGpxYrqpXY0FPbJ7fLfis5A\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/49qHJcvGmI6BthoASQyF5MXZSLxvglL+Ei8=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022qCtjXfdiLCfDqWhrpRHPYA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022a34038168778e3f2f7ac6d58974d6fd336c0417c1bfdb41a7f1fd10b5df76701\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A678.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A678.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0596\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0596\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0596\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}