{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022g1zZX+EQ26ivj5\\\\\\\\\\\\\\\/oPz9nL8GzjZQAOZSBqOeNboqD15VLgC\\\\\\\\\\\\\\\/Au5Gp1RuuvX3R7ll6EM72T2nPG6JrTBiucOsSrLvQnQQ\\\\\\\\\\\\\\\/Al6hQj3YTaKpl1wOiHxzGla3anhX\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/XM9XuUh1FR3fuKMO9jiTX4j5AZNt1tYGgym6iNJvM+0GyEo4xHemyoeq3wxwHDRCsVWBPN\\\\\\\\\\\\\\\/MVhLqH\\\\\\\\\\\\\\\/CVjslK9A6pgCBowFMkjQpE+0dvUyTs3ndq6XuCnDbQ8pwLzBsJB9lCi04SAPwE9MUKU4GOFSYbkZe46Q9xobByS05FsnxIMA0R2vV\\\\\\\\\\\\\\\/F2rI0AKGu8tqLVQPG2ERZ5Rn7atpkQAw00psnSi0kbjdHF7l\\\\\\\\\\\\\\\/QHNKC9SAKjYb3lmZqriKcES3Vw5d7Gk5li9Yrq7ZqhdTUhVRNW65r3IKqMr5ExLEQTHU9T6eVpLqvDp0sQWssfk3s95GjSfimbJNe8aMNKNZHTCrRxb6t+cg58uvM3Y6f4Bkrn8VaXMmqmU1dBd4jzLlya\\\\\\\\\\\\\\\/2nMltlYVHYAE9LncW\\\\\\\\\\\\\\\/osrEWLwmI5fgBVQfAfundvVqBNCHHDdS6XlukpIx32FjmaLKvkWoh\\\\\\\\\\\\\\\/jS\\\\\\\\\\\\\\\/cFlv853S8mn+6Aecm1cwPotMEIQEFjF36z\\\\\\\\\\\\\\\/p1jQ9oI6QIaEZO3x+57J6L+gsHFyrdazUuphTm35z\\\\\\\\\\\\\\\/t+ckOXRRN0\\\\\\\\\\\\\\\/FPYGufqYm8Rdo+X0\\\\\\\\\\\\\\\/v6LTjYL+qw+XewtDJwWzfeyc7Tvmk0Hl8DqP2PQGgcUey9Pwq+wffK+pmCd9yHspuJzBQN3ySDezQxNim\\\\\\\\\\\\\\\/poMz+3mEvA3ltOGTLnaOCUxe3GXac5NQc8ZngDz1umrFk6znRFFujIHL0cmX3dwxgE4g7JyY3vPLnG5K6uLu9wkBTD6sXI7jA7+uoYxK7cak4Gj4zppIY+XEw\\\\\\\\\\\\\\\/2iijxmM0ovniImME7cyyQbyFy6+rLUTdaggZk9HztuV1X6R5uNE0vL0cFrDE+49bcU8X1IFT+atp\\\\\\\\\\\\\\\/GGNRGlkU249HwgxgMwpNEpuCxEZ3JTVPPH1+\\\\\\\\\\\\\\\/dlhIev3vhQcCb+sCfnXgS9LdHNLrS6+BTOaSSkcdhgv8jFvWup092eonbK0LzO4PyJZK\\\\\\\\\\\\\\\/bVi0A6hOX3n\\\\\\\\\\\\\\\/NnhgSzobVrwCSWYDKXt+l3lLU4u4vh\\\\\\\\\\\\\\\/3ZlfzCdbdTE4hlADLV+d1f5wrjAVgONZ+cNNwm1CoF95Xn3BmQXwbOiWirO9ahvtWj5zxlGjC9RxjINb+mmL2ijsgf1ZvFc29b9ENCgZH30SIr6LYLWEJ6qHVy2bTokUE76oW9FJwK3w9YzBaf5A7fAPCCGkZBcVABXtl23eId5F0oDNSJKfjJjUbp5or1CezbOWiFZHipJfYNvlDnqr8R+I\\\\\\\\\\\\\\\/ruCWOSJxuRBJewdZ0W1IhiNkoL1Y4YDDl9zxb49MA+SWK608ijACdJnhxJAzPaVE4uYvCvRiBgQ223uK+SyCfpm11k+91XStpL2CifiHSCdWtAwn58BBx3+b+BBbqR00\\\\\\\\\\\\\\\/CosLvznedzNEcrBTiWMXEdT0OI5YPmmiVTRNVnq\\\\\\\\\\\\\\\/GAOe2gdbbESitpuE6MGG5KUbV9lkwFoxbAr+RDm2roROsdFrUJgompJ7P7Ji0V2iKxcdNSqjK2LLk1Ig57SL0hhiQjRx1H0hDwbKCY2f3HhyZxSapKPS3s1YEa8YTjpJCoeCA1t7vrCIdwl4pZAaIX2P\\\\\\\\\\\\\\\/qS6YbbpMBlARrSHfQlJWsepGo2z0BBy7NzI6e8C77V2Bl\\\\\\\\\\\\\\\/u7AQ7enotrhXS5ng0OYTCtLwK5uP3KzEyuu8EGQNmFA+ZcrwcQiqSfHeJw9Qp79WTf1DIk7zTlKmiBAFDKvcsZo\\\\\\\\\\\\\\\/V4I\\\\\\\\\\\\\\\/uqq9sC8NSLlr9WcunfM34YEnvbS3Ub1oWw7LyddFIRjzunapzs6YYai3ySh9sZtmKoGVFuDknJePnAcnXrGMN0JlQhXiW\\\\\\\\\\\\\\\/isEE8Mc\\\\\\\\\\\\\\\/rI4Fb\\\\\\\\\\\\\\\/689rBLboFg2dwRnIxARt+Q1ORBXd59RwizvWpmtryMLGtNhJ7sKiUhjitCOkEaU8zWuCaR04SyqTVCKKK5L2d5yd10AE7OR7lOFKHMgH3XaCV+n+SmdlaTUVRtI+k01AsfAaO8KETvySK0RE5A\\\\\\\\\\\\\\\/KJ5FgToYQVPCHHD5XFTdHFhOI8oTXBMRiJxyrZBPcJ+uDgtGWw\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/1v9XpHfDdoFyeozyFVRXHRD+DIu9JzbndWSkEokVe\\\\\\\\\\\\\\\/Kj79pyEWLMzcl42UDfpKfQj5mKlKMVWbrqSkY7xXHplqwGah+XB6DWQf9lx2QwLRqbC4n+FqsRKjIF5oh59XPc7HbvzROoZtfyEhbPw1HAQiLm\\\\\\\\\\\\\\\/J5bzzcp1bfchLwCwASOm1A9+PXq60cs+leQ2HXekNo8SmYFoquF17ItctNaiYBv7+V3h+A1auDPYp90N57rZ8L6byc+Cz6l+Uz9eHHXruXdb+p1t3MkM0Z2Rf7IiDErCjs0lhaEoOqM2D2V90+Gp4JlB5pPuJsD6oLTpdQ1N4\\\\\\\\\\\\\\\/qj\\\\\\\\\\\\\\\/REdWCrlkvf\\\\\\\\\\\\\\\/sqAtvwF+vcJgzqZevpypWp+\\\\\\\\\\\\\\\/aOxxSIoZzc5r1\\\\\\\\\\\\\\\/Oz\\\\\\\\\\\\\\\/fzyeu5Xczih8SeNy5kGZsrktg1EOlwIRio8dcZ3cn8VjTEekleFt1oH1C8xq2zP5u3EasLuoWcda4KEgW7Xvi3H8NnzpyquOtlxZR\\\\\\\\\\\\\\\/DlOpidmvdHWgDlNJNTCke9Y=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022ZYt16E1N8wMiXgbcOUss9w==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022fa9bba9061a847c84353ed56cacbc471a2d74562955e19d9196984ed8212612b\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A771.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A771.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0680\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0680\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0680\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}