{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022fzl5456LHFPdOgqR3PoSsjz6PchFE7e9EsVwl5GcYglOaCABf\\\\\\\\\\\\\\\/ZI25AWhjXpcjAEx5doIMTPC8eVhvSchlETl7O\\\\\\\\\\\\\\\/lLvIRrUvmC57p8bPLBCh8yr09rTZ4hVpYntM6y7tvTGOhTCOT6iMVBvyrvb+3TPEuvCJ5IYk84VPZwSM01WygPNKS\\\\\\\\\\\\\\\/nygXxGCTCDWSJp\\\\\\\\\\\\\\\/MhjqIU+JCo6rQpB\\\\\\\\\\\\\\\/OalGGZxeGEmvY7jyr+mKNPCYgc2+3KPXvn9iKIekGnX4XUviu6h8gQc4nZmFqQFTyCL\\\\\\\\\\\\\\\/Lf\\\\\\\\\\\\\\\/RHTHVbmXiXDeUV1APlypdbwsWtD\\\\\\\\\\\\\\\/7ixVM6\\\\\\\\\\\\\\\/hn1XNONoojYoWAaVyhYpDqSNIAW+fBqH6weHXh0HFIggrYDXGTdtZoOA9goeGi2xZHRDZ3yZKn8G9oTsFbUwnjVrl+WFFi3pFtbGy4OAyXZzSz52B7mlFeA3x9WlVgPOuFIMY2JCn9fwVqfRZj4eW2jBfYddtwcmJ503UISRScxWWnrNM25kDzJuyGTb1FCD3+6CizyndTJF4udduZ4eQRHv7Tpd4rICM+k3tg5GgnRx0O9et+QJpwWq0EdK9djQWrVXpyYIqTPWCF6zTrPFrzpw8iZFr90Jso6K2Z9cECk4Xb5Cd+aLKzNOVX8GHwng\\\\\\\\\\\\\\\/uSLvQNHM4qQWs9hCDnZGt6WgMODc1go+kQm+2ViG9v2mg6WtHw7yW59xRvbaM7oeyVczC\\\\\\\\\\\\\\\/3Ozqdfpri0h0aSSxhLjEInIztvTEVpEBJUhQOxNBwMQyAVyIlaWGZC5ggVbz02EdDX+dBx\\\\\\\\\\\\\\\/0saf+PkOzoCkaTsyTqR9ReDWLe43Pnd20qlBJP0\\\\\\\\\\\\\\\/uOWvk2XRo+Dw\\\\\\\\\\\\\\\/JXl\\\\\\\\\\\\\\\/Qku8q5tcrAF4WdB+Wan3ZiAsD\\\\\\\\\\\\\\\/Xfogdr6EYIRkUiyRjZmP2qGOLMIwXxdpMJi81bUKk6RNJOp2YMRvcKwujA4dXL8OISCWn0vIzGtv8Ty1rtTuUokq0pl8w0P43c\\\\\\\\\\\\\\\/GDtu7mS8nX3eFeBYb4TGKFPe+KntIbMXIYy3HayBldMuiZEAtwon0tQHLgHGYan2FhaScNU0GAhALatqz\\\\\\\\\\\\\\\/y1M6JmLXL5mZikxC\\\\\\\\\\\\\\\/2v\\\\\\\\\\\\\\\/slrpw9Hrvm5CwFnEP3YdvMkjuvDNpu0hR364af+p6ec+xb\\\\\\\\\\\\\\\/pOdFNMzSOH5EnYrga\\\\\\\\\\\\\\\/WCwWTL4JVX3rAhM\\\\\\\\\\\\\\\/5kXxFlYkO1NJn4adQ58X7mBMbp83A1dMJduNPJG6IRt1rlrUPCuDGzD5vVIXME1GJGWX3jay9EUqejM\\\\\\\\\\\\\\\/NdVKr4LkQmA5VgciQYQKCt4c6maFtp9TO0cuR8EmqlKm7FyRUPEXiQKfnXWXECUEm4IxUbh4ZrhwktQmKHTA6NN4YJm08HPklYlALuPt03iLFGfdf7weXV7+XANlVO8yfM4YDiagfHB0KCuyCyn46aixngNn9AmQVPAkU7ccclrXJVSRfElx24GA8TxXTy2wQJRoPunr3mr8Hh+ehXReIQjfArlrUE4MamRo1h9qz8tu4sIbrMnufUzWi+j5ZhavoGbwXGwl+hUBKDI8JKpfc++J\\\\\\\\\\\\\\\/fXvUpn0makdbAk5oe6e76matHTR9znbj7DMzEiLF8nDn3mTtcSV5n9JR4vLGNNI4EWmnE31ixMK0xI\\\\\\\\\\\\\\\/4G1wkFWKESASLCqiPaAfX0mn6iE5E47WRmqOVNuc7Tx8oFA9nE8KFWr3XK0vEAXCrDJ9C7SqSZ\\\\\\\\\\\\\\\/Aj9lNXrPgsjmFuA3XvLQCUj4x5GdWolb3Jtbl3TGi9Al9dLQfPKnI5coFsFOVc0qr4btVXqihrnvUq3xHwc30Qv14Z+PG6GGsgpAAABUk752KLqmJXFEsqP2MZQZ\\\\\\\\\\\\\\\/Gp8r1b561sKBaK\\\\\\\\\\\\\\\/RGq64BLsRYFjn0nfOGL9IteVrzB5NxpP7+0ognVGM9jzRZjJWZ0Z310ZldhiWyqZdZkLkvoglR6L6xwp83W7cHsXGxjrW6OWPJD2SgyltZTSaB0PlPjGznvoRBbyMgNkE8ydiPNjPrIWRE5gaH\\\\\\\\\\\\\\\/ZLHY0Xv6GQxgDYBQU2m4Wme8Ol3xWkjD6yvI1pL9Om7JXYQSZnqxm0OrNsJ2WjbX4Ab6uymfQNyyWa20snlzt\\\\\\\\\\\\\\\/bE4hHa+BggMIpny\\\\\\\\\\\\\\\/UpqSoZB6RY+z7yD09adv1S6OpJb5ZqYOks46uI2dS1vcUTbywAK\\\\\\\\\\\\\\\/qOPkrREbTF7m3IGVUMi2opDILAIGUVKmOfxq6dFKecn+hD\\\\\\\\\\\\\\\/C6FKpWGFN66sE2SshiJfQveec9rfbgmcOfMvUv4Gd4d0AopmcJpb68e0oEUTmFqmVGI24MnkQl\\\\\\\\\\\\\\\/cstcXsEaapZZcRkk6D80OeZj2TMp67CdKhyYfaUvxbLe96TfpNZUpQm+AFQHqBkSphww7UX+mM8zoCUsmyKbMwbb7CYtZvIZvG79PRPbn9tmiA0FIQdxclptoJw4Xu8FvtNpBDwEhPpy\\\\\\\\\\\\\\\/nj3nxvk9nDTS0oP7324SwCHka55\\\\\\\\\\\\\\\/OU9A3+vcXtpLtyqzhJjeBZVoSRAQ2bvSMtqRDFF8ccNyEVZJ2FOouQSHGKdO27WItXMXPC2NDl4pRsMJbukwHa3LbHQVsdthJK3y6fIrmg5NpUf94G29RpatHI6eN22rNdZ5hnp2bA5FhnT849fFefoF8oISOdyx8xWGYMPn2b136xZqlDDfeyfph8LkVGQTAxXFZWVQBa6+OlSEKy6wFw=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022ldnGRMiBd+JSmMT4FNt+Ow==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002225277ca00b8113ede1b490f7545275a8fb4636e47e18b02c37b11d775adbb835\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1583.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1583.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1424\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1424\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1424\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}