{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022cvlfavbM6ohvciWi\\\\\\\\\\\\\\\/9sjEYjKdW5fTDmxaTiE\\\\\\\\\\\\\\\/oiqvNrE+VELMqjeqQV+P9DPwMg7wog8ePyRDG89dIiMkCDTspeoDtZ4QRPxdR6bvW4LY6qd4nh2+dvyuY7AuCvtrO8Mjyy9HQClSftoXmN0i8FUdwBACIR6CJhq9jW79jqPjE3h4Zmavde+yx7xJgPFrtT1lx5IbdfZLpcgsw+LmhgZSCKTRUbr+mb50O1RdFMe+zQOAmH1O\\\\\\\\\\\\\\\/DIPFzjgVWiDafToGhsVNPD9kCza+\\\\\\\\\\\\\\\/MnT2Sl9FFweQwEqoffQ91z9uRZhIfb2puTeemhtHzkY6\\\\\\\\\\\\\\\/svams5BjIzVISBgAgOMvLJu102mncBgtxLdFHKgP3YvNLEySlYYIM\\\\\\\\\\\\\\\/gynev6Aaxx\\\\\\\\\\\\\\\/jxceQPmmusLGTbfctyzPVDjaMziy8tnxvtmkztww5iuQHsleSTEthBnhRMRTlwGK5SsDs6KONDHmidIxqic2lfgY\\\\\\\\\\\\\\\/dp5nmGnumxJ8N3S8KYboo+mjaEljN79RLIhRDI3EbZONuYvQ8C5P1YxNHvHqVsZECT9epLVgzcbWvNmVoynwMRYGDM227sVIsq8cdnK\\\\\\\\\\\\\\\/mtNcs8XdR2XQK7Qm2atq0u8YHHDct3l4tTVy+R78iHBJj512WjE07UMn\\\\\\\\\\\\\\\/fDJlcNXT8Ij+aEiTCmqkI\\\\\\\\\\\\\\\/Saw7Jb3kzrRUMX5kA+O9zsZ0FxvGUtakKyFT53HeN6sjPG3o1jzKHIykbPg04fZggg5i\\\\\\\\\\\\\\\/waLTy\\\\\\\\\\\\\\\/zkJanuYDtUA4FGi9Zpw0CVb8+hYU2e80nZ\\\\\\\\\\\\\\\/Lqe6wzxc1a2mdHKfT3q4KeJuvAi4urYulmookwLuVb7RwWKHmSme\\\\\\\\\\\\\\\/G5teveLXcTUYqePfMM2jNN4FulRSgg9CqfE2u9+ioA3GOpOeJw7KYv6psxGy51g47fnTx0UlQM7OAd9Wqx3Zw9zOhPJcMEkkXGMTpBnGj7VJDIZJPQw1ljPhYNWs8nF0FTe2mEQUTGC0HrPX9BFowIf3SrG8QbNL3R0uEKTinlN0C\\\\\\\\\\\\\\\/hLxNpLi6LHkbnRBOi\\\\\\\\\\\\\\\/pI\\\\\\\\\\\\\\\/ULth2m5gvYnAkub7r93bL1xgBD2XR+M2ZpVdq7uQsp5ZkDZ5xVE6HfZCYYowwZPidJ1U6q+I87bpoE0iSSWxsSS2Vm7x5NcyBhg3Kriki5OKsr9XWgItPAIeWI+S7vHvUXXcgWCvuTRjKysh16dkI5TIPwR2N6i2193fkGOv2AAyWokt+ERe3FC2ISzwfEf9tmHn5GbQ0zwsKuCvhzOp43oPztxC8co51mO3Sj77rQIwdYe0HUbsbBsN\\\\\\\\\\\\\\\/lana9z56v1Kn\\\\\\\\\\\\\\\/Fe\\\\\\\\\\\\\\\/F86vxAR5UJ0xhzTShWmKe4bENndbazzOc+ARRBARhSNuI1Uhn9q8MFiW8VufRONJ5YlLz7w+VR4NL7tyrIalDApX47uVpShnwtghgbbqDss83Bq4jpaPOBmGr65RioJFFMMvWfwcztxSruTjb7usSN0yE+Rogf81yrhdvNPI2xXCMsXbhXD2GJhjq+c5DxVhhoXFRPyaF\\\\\\\\\\\\\\\/WV9+Le2lggGIhJ1a3dY3Bsub8TXmPJ8hciBHvnoXzvQDbn8a7aF8\\\\\\\\\\\\\\\/rpGv3TXfg2WSpNtBMi\\\\\\\\\\\\\\\/pZtEvVpAuTieTd2X3BTYWNHNOYQPf3NKr5HMqzNnda65ARlsh3o3B5RlfqdPvXsAfi0i2CO+4bBgSG1ptPY7KExGp5r\\\\\\\\\\\\\\\/ip7ZZ+n40N\\\\\\\\\\\\\\\/wbKioDc37JJ61BOTyOXiWA6hAHALp9M9Mi6J2aAHHSmvgro4KqprTqUt+iSciNskCRQIwpEJ8uwad5MZUHAmcMX0lcyYqc\\\\\\\\\\\\\\\/YPuXVAx9PWvORoaVNzZsOXx09uG+2kHvALAes5f\\\\\\\\\\\\\\\/kW2dqWNHGQUE\\\\\\\\\\\\\\\/Z3f32kS\\\\\\\\\\\\\\\/+f40Yjiish8ESAGqAf3r\\\\\\\\\\\\\\\/Fjy\\\\\\\\\\\\\\\/WnRwXGi50qMdbaeIiEDjZ1KzE1PaqlWpDDiZbVfeeGti0LQbX8PfpAaCwtpYuU1JvgkMP9X1TFOzPAz18h3IDgD0rJu5jpPQFfT2SMQW7f51Lyw2Zlh2yfW47AWKD5u60jKB0eFfvJoz0ZgD\\\\\\\\\\\\\\\/UfHWZC81cozqQopeSniFLpgy1fWyBxNnVZKl6tB18kSuTbNj6GMBWjUm5WG4fBUGbdwJt35Zt+I\\\\\\\\\\\\\\\/Za43Q8UhneuLKWiE8Vdxa1R2mtPAxhLm4VeOLFnfKurd8Ygaq9UWwB28EAuz0Oq+bgrzd\\\\\\\\\\\\\\\/34CdM7R4wJy9BZ\\\\\\\\\\\\\\\/6rDKqSeZQyCUoLTlMAWfQyLa1s68oCc1t1xPnAHLzHJMWDpB0eOKmd7EIpW55m8pBmIOsa036sg3G52bDDyH5IjVGcIPZFrcNg+De6eGf\\\\\\\\\\\\\\\/lCKDLmv01GDyh9uXq1rkR9RaVxERHvgEaOr8wf0MiArJZuVhK+iyQg23pb\\\\\\\\\\\\\\\/hCJUiwg\\\\\\\\\\\\\\\/x7EvJ0IjmLmV+wpD4ShmG0EY7DIqLrNYGQOQ1xT9XmMiLLvajBrw6Yr71o\\\\\\\\\\\\\\\/LIuW0P4xlr1MCkHAMHjK66ncJIHe0UKJfSISeEPf9E\\\\\\\\\\\\\\\/LCZhxIrqqR5p0DJ3VCvsx1y0E0br3B5pKeniwv8QrGlwul0F4PgLiPLZQCIte6sU\\\\\\\\\\\\\\\/45CrKxOFJ+ltYXZGcc2IW8tMiHh57RwTV8D9pUExhCTcSJpC9pfjyxxAYBXtrxLOHJpKaIktrPYArY4TM\\\\\\\\\\\\\\\/qr\\\\\\\\\\\\\\\/viK10rBze\\\\\\\\\\\\\\\/q5eBBMKKa7K8+i58CakZAg+RAGOo=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022PWsIMcmyjbpOoIJ7ikQCuw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002215d6d281437ca4f3fcfb04ccc4e21b70a0c2611e971d90f9d3dbf2aab817a148\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1188.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1188.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1079\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1079\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1079\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}