{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022h+oJRLLMM71Fm6DPRrq8FfWYRJHjROBcNoLsqAzBuZdakL5brh5JQN7Z8q0AtWfca6YsxrK0CBYVOb94PhM7JkUtdiGB\\\\\\\\\\\\\\\/CTzPX09bcM5BV4NeLGBnGk9lqhWBsAB8Z9q0ahbEtS9PT1zKkpMA85BBnUDclWVo\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/JqTPoUVphe\\\\\\\\\\\\\\\/HJjidBk7aULXYFXiP3LkhWw4\\\\\\\\\\\\\\\/RV+ItdVRagLDQS+JF3xedIF5cfv0FjQLrgwo2ia0ROYYQH4RNqaZTih8qvS+LtuRlcu120H2wiRf2HJp7HaWw9lxULqah0pVg8HurzAV0OTXZ6sm+gLk6vT1eE45rSRSL3vqRDHR9i\\\\\\\\\\\\\\\/vDEHUo8q41UsYb5D4L+cpjTfcmLEHULfJZ0JUAlrGNUoiGhC3ZVbG4txoNsok9QyoBccXfciHtvHDaU9zoTjC5t6tE6sM5+dH1T4zW51OI3gJcTQneTapgDaTnJzsglLIVtWn1\\\\\\\\\\\\\\\/YkVJr0crbYRW4Fgm\\\\\\\\\\\\\\\/OK01CbHLSWx8z64zvmIQabICk84QV1i0pZSkpPIfAU4QvT9Wgka5iNb2Ho5lXo788oTyUKhwyhytQleX5OWPt4+mHhXs92gojyDsVyW9TB+6KJX2KWAwb7XGEz4u5vKpBCXkzwCXYJy8XDDE1UT5+2cCzJZ4WxOKQrdB17mCLpTsrFEdY5+XJIvJyr\\\\\\\\\\\\\\\/ASg1WL3xAPvYtyH+MrFOcktDTp2UxIh5GIUUWucho6U8padMZf3+B7i\\\\\\\\\\\\\\\/Bci56SSxO9Q3N9O6sqh72Dq6Qokib2mYud\\\\\\\\\\\\\\\/YqVFW+LrPxH5rHdFukqIysHX9kQYsM\\\\\\\\\\\\\\\/isnkko0LiFVK8dmWdboGIp21bRHAoJPH1wyXRV10+2+ziJ8C1cP5SXDrRJyqe9s2qtjiMjbxILcAPV7yXc2vAPGu9ZgZ2suaijzUp7usjY268oxLvdmc+EgbXZUH+DCN3mTypj1qVrMLy\\\\\\\\\\\\\\\/de1UlHjNnVYCUjG6VjwXmCmXjqDQxZfJcNkySGBxaRb5ZRFAjMCnwvTpZohZqHMQtdedS1WRVHpe36y0JPMAQPPSPpjLvxrFXPkMm4eBfuXm6O034BFNVSOcC2Cdq5CaVhQpazXjuQNFyb6UWUToNLFOg2z4EmPlg8KVmQ8ZLHND6UhCU7c3hZPpCezgEq13Uay1EkUqCIMhW0Im\\\\\\\\\\\\\\\/qAjBAQ1i6\\\\\\\\\\\\\\\/0R23e4W1huP2CHiKLYCkJfz9h8GCoRCPxisv+F9t+Beji2oBKd3XsB9cKuKmAGIqgJ2wieVaoWQwDS5zOzlgG1zKJalpJ+p8SrWrPZBSRXg3pZqY\\\\\\\\\\\\\\\/1YK4xxoUJKRwG9sDC7LlzuK\\\\\\\\\\\\\\\/BMSa82hR3pyFU1DLehhE8LIP+YY4M3loAi7jrAqIdiv+wnxQj6hlbO5CRLlRuVr1zFWCKDu52SARcRu3oL8O1t\\\\\\\\\\\\\\\/qRObw28DzvdSZeZUw3m7Z3CpAUrGb+YiU4pcPZMkT\\\\\\\\\\\\\\\/GnabzaXieXWcCCf1YwQ9abit+rnd2sefgioJFVywb5mZvStmtTvxiGd7mDShEtqUet1ZUXxOXECiN4lsWITL95GH91Wra8uk2OFjNm5UG2JR1NTWRv4LufksbLmfnsmi4QsVpjtGsody\\\\\\\\\\\\\\\/BrfNXY+njdMJ5uxD0oJJMT3vS\\\\\\\\\\\\\\\/m831hLqO4JOefbNLOZQ00csuq7pk+MZONE60T0LqIIYq5xcO+uyzzXZuPzjJ\\\\\\\\\\\\\\\/+tdcvAyf67t7UUF8FcSb12cZ7nfFgkag2BXmZ72Fdzfpe1qG8E\\\\\\\\\\\\\\\/3tncqLS0Jx0oAe7kdQiU5OBCvZK7yPh1PiPZrIN+4NZANURoJ59\\\\\\\\\\\\\\\/aBX\\\\\\\\\\\\\\\/GCgfwVp0ioVtWrj9BQH4\\\\\\\\\\\\\\\/GG06q3zyclKD7ayZvLS\\\\\\\\\\\\\\\/A4qguML8tg8gbLhJH576g1KBFlNgyPJWDe16V\\\\\\\\\\\\\\\/TE2bpy0jTkC0eoCXmWjvw7qaYkiQNPLfk1ww2oIwmfCFIyvxQk2GTcdjsufoprdiayiKbJxu2629bZaAvSDRtImgUD2H8k6Rg7IxvE0K98iK2hDuZyXfLxdeq8R+sOF2qr74OcADkG0v16y8LH6+O3Vqot1o5j1YESKaldxTr2SxY3RzXhKt7NrAzZyL4Zl1PZvgME02nI2Vr040XLV0WRAfAMI884XgPmkmv0XCdyU71ivAPT+Erw+dkPZTFJ6ggyVg5+XiQeFt\\\\\\\\\\\\\\\/FRUDFxqMVoGL0BQxg9hqsJbScLv1eeDtAz2T93xCgHBf\\\\\\\\\\\\\\\/dQlnp6N1Y2kPbOQwuhXn8\\\\\\\\\\\\\\\/kCdI5NXTz\\\\\\\\\\\\\\\/3ptfyaoh7vUcHSzAubI7JajRj1ytnXx3X+PNUMdaJTj\\\\\\\\\\\\\\\/skvfxXQxXlse5ZRHg8dvwWi9k9m62e\\\\\\\\\\\\\\\/ADqe0MbnV0hONJ9hBGbaxFrYm+xNHFypgQmygP0GjQrxH91RnVzgLwkPIzDcv3RwNKLQWN2dgQt6Mutbaqlo5VIIIwRDl1+gsrSNrRGZNUSQRBaFsqOi5qGwNmAlmWvMQw6sEyTfUu3Gtsx1mHV615xtcPC\\\\\\\\\\\\\\\/igHjpqHDy7Rnezm1msUeoupMZqSUTQkknb2xCrO54EwSu0rBzIDiI7tTeXjTLAjhDqUxcJ6Tu+9GcBVpzXClMswbZ1QnORAXvvWGzz0uenTBvA\\\\\\\\\\\\\\\/F3bh25JVRn7maqdPJ74UXrmdRcWJxwHF7tDUQQt3aCx3nnZgUSkZbNLNP5R47Vw+7QD5irAU7T7xfHo=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022wPn4diJuNoG74SUf4rKjNg==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00223f5ed32d659eab678c22aff5c938d6c9f8df14b0223b3817777ba404a9c416cc\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1540.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1540.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1385\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1385\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1385\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}