{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022hSSmk43uA2J5aU5mNKmQKLA\\\\\\\\\\\\\\\/ySLMaEi70zVcKyb7EPCy3XGpNn3xf3i95lHzIsqdOo6UBblqeiKT50Ndzqr+puFa6vIzWVBFFZeAd5WoeC+ONId+HyIF+HdijdwuasdcN8wpp+KbKTJs0FbYvRcOvmhlnDvHFSLhxatW8JF\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/9QArh\\\\\\\\\\\\\\\/3oYgrP6yhi6VL4XmpO\\\\\\\\\\\\\\\/9zVBW8+z\\\\\\\\\\\\\\\/RFtEK0sdJpyRJjD0jYEFJNVPefcTfKSEMeyCDGy3Eb\\\\\\\\\\\\\\\/+c4Nzo5vW0+7eifajtbFLk8O3YUbnIBYPvTiq1nczDyPDPAIE7XpUQn28R9ufR9REg8qhEDLgpMzKzfUBF2FJ4slU+RCFttjcLEqRpI+TlQ13XSy4Odhw0rSpuI36ji2u3kd1v6jXlbRaiR5a+8F0YPlGNfBQgNu78spUexPpuKmmW7\\\\\\\\\\\\\\\/Ccnx+uP9sNCT68zEaVuFMqHt+9ExXsntQwYFGQ6pVHtNF\\\\\\\\\\\\\\\/qk3o5EQVQ\\\\\\\\\\\\\\\/cC7DR1zWP+DiCYb0zn1Q5VUMqiPCksXoLo+J80GGjZvJTvJthaWrlcTyQof\\\\\\\\\\\\\\\/FKEwgQRZQAip53VIVYQcpgM8DMmEMRPxAZ53TQLK\\\\\\\\\\\\\\\/1UkE7DZuOXeXIyl+L1NQ3wK8Hs0RhP9fmSLSvUVMrAHe2pT9H5079PWNlJXVI8268AMjf3KvRoOFwGeFhi+ocKE0gzk1DbD+QP0ab5W7PywVRux3kNIVNt9EEqDaAsUscVugwhgC2ere2sXrTNqiC9rN7dW+rU1Oumi\\\\\\\\\\\\\\\/4m\\\\\\\\\\\\\\\/bcfE4dbd+MgBhXKALY1QRVxL3S6XjZiYV16x0UMpDuPlNaTT0jA75IzbGJ\\\\\\\\\\\\\\\/ExwyEEDuQ9+\\\\\\\\\\\\\\\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\\\\\\\\\\\\\\\/78ohDRPhpUqT2iDi+OkVS9KjEsGYgurOk28vJ9nV9hofwWEF8h\\\\\\\\\\\\\\\/jnLqghLgAOeHX6qz4qZwZ4JIVTZTkvr4SkzZCgcMTg39DeXK5McQkK4f3pcRUP3EiaowqdJQQyEBtkORRcweodzZ68lLoouXmu5YKTt1AVMvP3cA7CwVhJP7TluSHV0gOpAAXE1jlXZxqySpCa6XyhY5hId5ZjCADlNzblC\\\\\\\\\\\\\\\/6JRLHiqwYY\\\\\\\\\\\\\\\/6qczECl+xNuZ+0bWU573MFWG9jZoJml2xsm8MDNi0hyF5e7FGwoT4R2q85aWPxXiOss+sl9yKu0mVqZJxJsI3J4\\\\\\\\\\\\\\\/WGqdc8qyDwSk\\\\\\\\\\\\\\\/Fxhjg7a84yB8Z4L7aRa4Op54RAXPzP6zaqRicPefUzF8CIujg3wnjgGXzmzKQo0tOrxvZlGvVWOJsKj682\\\\\\\\\\\\\\\/dkav0qX70HNS81CdMqB79h1dfrnm2LR4j4cPFjN95UpiaDCpbyElZg3Kyc1\\\\\\\\\\\\\\\/kTUhIQ1ZpnJRwSN7yhHHE\\\\\\\\\\\\\\\/RWPlm5Lr23wa3J8VCSErZoiAy8d1NrsWixBRUSQvJOXVGUvh1AZb8aFU8MY\\\\\\\\\\\\\\\/A\\\\\\\\\\\\\\\/+dQdSoaJHXfGp+wDUKN91iLeANYv1WcQ9b\\\\\\\\\\\\\\\/w5SBEkW+AkYkimCvFL546wEslIl4yGZ7NcEPOWs6L+h1IQGlnGGMeC8WYazk4hqNYyVd4\\\\\\\\\\\\\\\/g+f51iApKTtpj7k5a\\\\\\\\\\\\\\\/H3IzQX0zmJrhLYEYkpLJaI0ccmptUxs+gvHrLnHW2dXSAZcZc3\\\\\\\\\\\\\\\/0pMTewUF3tBXYhRspfV5jm4itaOECCwSzrShYNQK14nmwM13aD+f7fe2CH1GfwGQSWxYaK6xmZarUcsaOtXAAD\\\\\\\\\\\\\\\/Q3FmCyD8m4kRwbS\\\\\\\\\\\\\\\/FugZuMfO14Iyatan2Sqv0pXfW526e1BUHgT3meDDj3bUzvBnD0ST8TG10EGkHq9R+bJ0pdDaW+j5QUQIjkbiUsNGctprTsfO1Htyltmxld6Dq6dERLCyIfTWfMthR\\\\\\\\\\\\\\\/o+HQKrsJUHYSeZQ5PNTdW9ET0LSwbVDCrJj2813DuVbVizJGZ4Ztck\\\\\\\\\\\\\\\/GexD9pxRaeqfhYi2Dfaa+wBSw0QrllA8LZIH8dY4unBKQ1PvsWCJBj42WPaiR3e7kTYtauWyhuZ1ymS46cZTwwx6snm2oF24zEBR60mkp1ywzzYPkNj0YYNNi1L9BdBuxcmonbwBePQOk1EhgdrOBc6GnXAPMl2C0m+hZkWepzzDwhjryzSx0iNcqjaoLngKTxiB\\\\\\\\\\\\\\\/uWJ\\\\\\\\\\\\\\\/oE=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022HoHW2Ar5nItLkL+CjUTOBw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022afbc843d6d803c6da8496bb3012f21d7a86595ee0cee355020d11ca5c0c4380b\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A172.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A172.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0152\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0152\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0152\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}