{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022gTAA68yIhiHJgNO75AMkGlWiCt2DXt1F5urC9KywIG5BgyXW8CjnJXGUNk8TlRSKpECNSh7x7MFMCqLsui8eHghd7WTrIilUAq1WGiCLmGDm\\\\\\\\\\\\\\\/rUA8SyOQG3tbra7jPX8CigxX2BMV0hq3c1yCTTzHoCcUW32LQf67S3ZOqHpT1nv8Wae4zEDkLe+H8LS7I5GeEpZ8AP6qaYdx+gnCG0XZZHMiwvbKh80KL8yaeIQszAbNoIqiLSyskY6LJ3xjod6J3FGzmAg8t4zBCT97z\\\\\\\\\\\\\\\/Sb9JWJqnZCo4kSjvwLokQ8oUDxRISArCTcljxgmpajFnLXo9onvXyEVn\\\\\\\\\\\\\\\/2vCwFdwbGh2l\\\\\\\\\\\\\\\/PNnYyy0UA32ukb8vqrRctfd2BUY8Tbc70FyHAivpypjMiMy4bi33d4KHaF3RDpSRAQgI8KPUf5UURw2U5F914j0QW4Z\\\\\\\\\\\\\\\/3L3ztMQ8yqp8P+sExpvi6FNM6A3gyqXwpJnvuOeJ6pyb1NDTPVO\\\\\\\\\\\\\\\/MgKkz1bCC+ft2q+w7yBF53QtUywYZUg1kKn+t0Y0HLRNOIWGxFn+yHdFOahlse7KCTakDM\\\\\\\\\\\\\\\/QeXr9TFjoY9AHa7\\\\\\\\\\\\\\\/Y3\\\\\\\\\\\\\\\/Xus3Ymim+pJKyBxr7atFQTbRqP\\\\\\\\\\\\\\\/iCQMZF\\\\\\\\\\\\\\\/XKSctkN99h0d1Oep2tZxy4Jwi4OsXE0rYnjWv6nzPXNHONdKi3UHlSFJBonWdiVHcse2KSbdX0YaaRR5G+wRjE7uo6baZs8\\\\\\\\\\\\\\\/VhjzTRKRNFAY1HUMZ85+6YRGYtFx\\\\\\\\\\\\\\\/5LgWLIrzh9uI4Q5XGjHQ3rApu6IUDLzamIHZ7+3L+TNPV+qHKj2fFnu6Cwin\\\\\\\\\\\\\\\/Xq5r4l5uPe68IbbQ0qIJfU11Mz+kCNeRO4v\\\\\\\\\\\\\\\/D1FMcxyeSu9x1JluHpui4WpwcklMtQ\\\\\\\\\\\\\\\/Nhoh9sIR0f4VUfLslER95ERtHHowTGgwFpSSr6Ypd5e\\\\\\\\\\\\\\\/h\\\\\\\\\\\\\\\/rna8zVlRTR7f8l7voyAQNdnzeCLhh3DG2VlDx+HtR0o+pePCf0haccs\\\\\\\\\\\\\\\/pmpUXGrfk1rfT0M90G\\\\\\\\\\\\\\\/NW21ziDyDoxrsL02fjrnkZvrLhCou9S5X57j6XOkPxuMU1k6XpV0LFP6jPchhnMTjUzVgEAHp4BVGJNSA18BCVXXnjJCJDQ0FbXT1rJSl3yDQiYPlOIaipSuCKD5js1nWf1lQsYiTVHrrrWwHYcTdSjW7F6cGrkTLeBEnEq7wj4R6LSaG4SUzatsnQ9L2Hl6JualuoE12VG7HsCHz3gDCvP\\\\\\\\\\\\\\\/z9ImEOJsg8BjNgsoyuFyHB18bGfWWPlTzrp5FakHbNm8yEoUVT4P7vcGEsjRrPwEdiPgGPl3tf3kAbI4zrWmPVXngFkz7tiRlzS3hZgu6QNDWtLJ6m2sb6GhEfydMQu0WjCA1nk7G4pjPl4NHHu6yTMuBzCG+wc0++H20t5VW5oD\\\\\\\\\\\\\\\/aNGtWhnRWkbJw3TxcnGuKQV+1Zm3wAoqqUE15WX5U574PWlB\\\\\\\\\\\\\\\/t1qch8sSRVYRgUO5GHsUYpPMuY\\\\\\\\\\\\\\\/LwnO+LM2kKd6QKR\\\\\\\\\\\\\\\/r1qyFrXbHG989a975R195YraFMIxWbZAeI4eLbc+deWzIYDiAVCbfifKiIoH5bRNfJFZOxVEXUOXiMPzFQfOlzLr\\\\\\\\\\\\\\\/J14ZfNRsQ89WwshRS62FAp2qddWneY3XPDktXK0gkmxcV79Il4CxDMGnkmXNkNmoEtXendo19Meln56nrxS3lIhtcHRRAppMz8chH46Gdo44WnvJskUiKl2ZQtuDVQLvxQtij1hSr2SNIXd0RV7j\\\\\\\\\\\\\\\/TNwKezHNorDhTZ\\\\\\\\\\\\\\\/SFMc4HHNhdeIE12FpOwSOJIYq6GObX2uvwvCQWgZ60vbZOnwJKafE8GTplivezFOHmLybLDn2Jwg8\\\\\\\\\\\\\\\/o7yTvbfM2Egl3EEIOCfAqEL9J9zXcaL3uzeCo1fO5buBoaVS56QRj13GMEGJ1a4tDzUrDMUU84GH7eC4\\\\\\\\\\\\\\\/OlyuhwkUaT9MO3B1OCzicKBMRESiAfwl8jshooEIyVuMav9nJjGYP3alVDOME+RMlo8sWYxIin9YYQDBgAt8okxbALK8xmwNyNRiNVgFEWskHq5U80nt5pbjEW\\\\\\\\\\\\\\\/sQ1jOlagKpRoBK\\\\\\\\\\\\\\\/bBPAUONGY0+5Ap5TS58A25ScGnHOq9T1nKS4oiQ\\\\\\\\\\\\\\\/3oX6ej8IiJC8VNB1xzSyHJ0qeM4uq38CpaoXpMACQxN9gihVO0T4pa87\\\\\\\\\\\\\\\/1yVSe+XphKop+SAhKBaQ9aiG0grsCD39vkh6yERQDZpHiNim6655HU30bt4LN\\\\\\\\\\\\\\\/VYXxmBXjOuV5sAYjbNb\\\\\\\\\\\\\\\/BVNxlRK2SYHbdGMC3SLO8FWZB+PVc2\\\\\\\\\\\\\\\/8bdh4CDyk9pI5iVdmtAm0b7AyBI78J8l322ICg\\\\\\\\\\\\\\\/BEsqzYvBEvMeXeT1hBWGg0jqu5wdYb6t14dBcglB7DhR6YRTQSzhBRBQ5ijgwRMl9mllOfcOrzVBbt\\\\\\\\\\\\\\\/xAfSvRcTXapO5I0nGV3mxgqzPJdA+4m7tVAVvDc6139f+dYrChwdnYmZ8\\\\\\\\\\\\\\\/wbbQ9ZpAZbQNmXR3sDin4giW3P32IV+hHL40rFZr6J+8eU3NRdinMTmVGbKrpC8CKoLuJoEtKBcIDYn3+yUuwzx0GgpB7XKsDJLJGVHOSAHOMHZvcjCjSfwS1tqk6EDCFhqDFxy71ZoPMyvB5IDL9lvD3YOySYT1O7FQkOM8yClPUbZgd3qZtDOkryJwYln7N+in2oQ=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022d2ISsPUmL3VyRQEa2XIySA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022c14dde80bcdf32573c35ff934a874819fd13ef6b7b25c274c8d794de5182e80d\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1574.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1574.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1416\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1416\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1416\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}