{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022RA+8bcQb+yCrQUyQbWEEZzO6xO7LcjEs4DMr8eU8MwUQSDewkts59opGWYAKb+QPpWyrv3Qsgd3WnljYhlxW5eoSw7fPPHTsgcW0EXmE0wQixBIxdW34sRDZzMOSMvhohw4ZOIRlxZN3idG8gXtr2XD8DfPPwtuQUrCF3G37ynbBCYRRaEfSa67Bamy0dxrgD\\\\\\\\\\\\\\\/nvq9RUfb5QlT65D7TA\\\\\\\\\\\\\\\/iMueYq6Iwuz0F5i3sSKkHAgq7nMwHy6WX82Z3WOB3qGPboWvXi6R4PJS0Mts93syyjESisRQ8BJrTGdFo+dB5+S2QV+90H8YRqRIeg+BSF0QhhcLjO5\\\\\\\\\\\\\\\/sV9bcPj6KI7LICbvmeNkvEVSd3S01\\\\\\\\\\\\\\\/yyCHXfTS3tinNl5jH6Ax7NekAFUcirhUWJq25Vf6opr6myrdlUE8uVjVyrXyVEX8q5Pe556gjKYuceRLSa6l2353Vq4sL1AKXzWYHBkqI010As9VkSzJJtdL0yt9Pr1nrjxDYjKYehm8PbGqujZlSdMT1A1mceAeRllP0SAxBWdzoma24C2CbwzuY6uzSHcFhJ4Fry2LM3GWfC1H+gEUPd907SAMXXTiOwbXKEOfEbPaQdfGehthJJF67UMe8pV4NuZtV2ghUBfz0Iyvv5Btx9MsV30IXvIlfQx\\\\\\\\\\\\\\\/sdm\\\\\\\\\\\\\\\/rBVXIt5uZO+ph\\\\\\\\\\\\\\\/lF8KlTaghAPGlbuITEwf\\\\\\\\\\\\\\\/q\\\\\\\\\\\\\\\/uc7u0lrjW3pagK4ih2hZrIhbPOxBrgrL\\\\\\\\\\\\\\\/mrJSGJmxEowb1YqOdCQcNV8Z\\\\\\\\\\\\\\\/E7bpGtGfFAfGI1HAnm8Ef058lE\\\\\\\\\\\\\\\/MINyIkhLMgOZr+kiql7Y984Ewxu6XAni5kux3eXE0qpKRx2bu3w0\\\\\\\\\\\\\\\/hgtnpKjwk8JOaLzgHW1DrCdW+4wBOaWkppmOzGSSj5oIazJtPcK+mFtpKHqOTVKdSAtdk9rd9gBkAVgleqWCR2evsgLiptPdEfAovC4iwXTE0dKsPnJuL9lS\\\\\\\\\\\\\\\/7mm2CMO0PLtstnnDXJ9EiKkzqNMsZW3mySu\\\\\\\\\\\\\\\/GgdDo2S2E+kYiID0EN+iPoCM3AYsUVxCaOd9Z9UeAGsHw4ig18hrD6uDoxXASgKDKg2LfQ92ZEwVly3TAxmvBvJNLsUWQESgpWoz+GSvoVp86xq2ioJ3R\\\\\\\\\\\\\\\/3cuqJ+FuRJ3D7Sq0\\\\\\\\\\\\\\\/b9\\\\\\\\\\\\\\\/AXA+eanB\\\\\\\\\\\\\\\/5N98ZP7nnuqq6H\\\\\\\\\\\\\\\/zeSyssjOq5v3Tt\\\\\\\\\\\\\\\/b3TT5bb2PHG+gkVVaKdzue+qLwO1DnXwcKmluaTCPQqbUmaabadRNC4YZmo2BN68\\\\\\\\\\\\\\\/9pdX9ENZk9zgrt\\\\\\\\\\\\\\\/kov+KshB2XEmmzZiBZJJMomTI9VGzfo0MGUFvCKPliS94F0orYOeR0F6WIYdcCpCcJkjOeb6bBdyYtd3zkqePv8VL3rboJnN5C+ogLfCjMrRgkWIYvlscKnKsxBJOxSHnkMuf7ziMd7XxRCvkOBAi3aw4eyw+QKComwNpXU6r81BTG0H2y+LLgySqPOTerqtF8gwhGh017PDyRIqGjm5oVksStLIDWKkwQUZXHt7B8SbZkanGlEf\\\\\\\\\\\\\\\/tCiv\\\\\\\\\\\\\\\/14bmJylMn74kTPDZP3asgXX9epbbvgpiJQDY5+5GlzpYZuFZ1gFxgLUfi4k2tpcn7agtncqyKm1Na1JcEFcYGWgyHH2qt4hpix2nvtufZxvJawql69e+KC540jOgdX82Yl3bipoMmroHlwHgEv4lf4NA9\\\\\\\\\\\\\\\/BtuYqX8mNO7cMM8OznrGH4VHhTjxN\\\\\\\\\\\\\\\/J6Jmawb\\\\\\\\\\\\\\\/jCr924GW02uulmUpolk63t44N4CIFd41tXprIIhAacjXfSJcauwBZrl+s7+4ZoIU6ULY8wlaLz6OBocwh4Ay7iE3eGioUiK97kJG1ECH0drSkiVLyFWMqnNuBHKO\\\\\\\\\\\\\\\/EEvL98Q8Patk8jPLGwY1M5BHs+Wt5O5ApJTd0RuzoLuret1TvG0Z8pRraz6YadT1uSH2kXJd1Alh89SEEHyoazUapKP1tZ+AW\\\\\\\\\\\\\\\/tVVqQOvKe7w34WI\\\\\\\\\\\\\\\/ZTxs2+96er4wPwYfl8snNRrVSuYdPyN1U+woy6s2T235K9RuodDLcDsrGJv70flQgVpUV6k8XxiQ\\\\\\\\\\\\\\\/U5KWQq+POLTGef44ruIp\\\\\\\\\\\\\\\/tZyk+DHZpi28e1RxFl5XpLRdyMpEU7c718Y2\\\\\\\\\\\\\\\/uSOKaOQIVYTfZKcOYTCib9M+7ZL4uQI18DZwh1FI1wqe7A9x4zStPchsFH1TRzSWgixvaLZkb\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/PPU5PBGU2lSuhN53xUXx+dbR8jCR5dBL2sjct6N+KVq\\\\\\\\\\\\\\\/kJLis\\\\\\\\\\\\\\\/Z2\\\\\\\\\\\\\\\/VKUT0f2MufTNT9H2S3rONlLEjjV4aB6vRATBTfaionWSq4jfwsH+OKzTmP4Ou4vt0\\\\\\\\\\\\\\\/Qx0Ge6toBIxNN7NF0\\\\\\\\\\\\\\\/fMvo8GOQufoCdRW1NBVNEZv61RfXCn2il\\\\\\\\\\\\\\\/mCH191mZYPZSZmDtAsz+msHTSEr7X001bA8ab5P896UY5Syywcy6EkCLYP3ERfv0hhZ+Y4nSaSdnrN\\\\\\\\\\\\\\\/HJtNfZJJ\\\\\\\\\\\\\\\/yJWwAxzg+wVjUV7k7TZjpSw\\\\\\\\\\\\\\\/F0uT+QH+s\\\\\\\\\\\\\\\/0HhCFrTtxtz+QX8J5EomGbwu35WsxV8dir9tTu4Iv4JUcgai\\\\\\\\\\\\\\\/oe6pyA4PVOipph3yraKJvmpZdn2lSicongD36TxlNNLt86FfDI+xensRjpGiKDx6hFzHD8\\\\\\\\\\\\\\\/0wZsJdloiu0bl0DX8PYWJXx1nWILUiHVhqm9avMZrnqDix9bEu02JGM=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022rHHnhx97wk72MkQsRMMJKg==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00223f50cbaba7ecec9ea34a7a6200bc76d0e45277dea2a14904c68d6272c196f1e0\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A324.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A324.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0283\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0283\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0283\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}