{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022LZ5KNTwZGGiBW7hZA2yeu8AUwJaCRomUYCcq8qQOkwM7l5cmsnClI7N67ZC80G16GwuYpR+RJSW+BJV91+l0KiIucAEZiJUK1LhBvkpcufTN1H1bMHpfkOD\\\\\\\\\\\\\\\/MTFNKAhRx24vtnoWEF7d2ac9t3mJL2auSu8d12AmK9U0Z4DWGlP2mIWCKzUmHA++vyNxU4LoR7pJ93dHFXq1yPzJC7uM8odFmStGTReg9rym5RrHOsnRgidMiR\\\\\\\\\\\\\\\/78N4FifP0JX9qSwWzRih\\\\\\\\\\\\\\\/SUToQYoW9hT6xJQWiK1hvCw+AqP3ieKj4bQ1nwvNHlvAQx+QIB\\\\\\\\\\\\\\\/DcwnMj+GG10\\\\\\\\\\\\\\\/MG9rJaFlor6fcstw0YADtD4OIcCmsAsH1xnJZMUNZ6KaPFSt8g0fmOy2b2HBWKxHztbVxpQHakGJ8GC5xvPInrmmwqPZ5u6y\\\\\\\\\\\\\\\/0NCdz5Nw6+3TSK9zOSo3fP3FUh1a1ADlZsBVrXB9eyvIEB16\\\\\\\\\\\\\\\/CEXzX0ONBUAVtzn5emc5sUxqM2leqxXQ+OpC28CX6BQdRBIMCUjjiwI5UfPewBsABlA4aLTdoyce7vwEg4ODsW7clzBYlAIe+lukH4+3cybJmmJkOxWWqO7\\\\\\\\\\\\\\\/Ppa8Jf9h0Zt0yiMjycTQaE3rWOhCoIGjlieCC9+pqv+9p\\\\\\\\\\\\\\\/x\\\\\\\\\\\\\\\/mxnwflbSx7lge18I09pO5sqpesy90qIiB8LrO2+PcIaEUCLWIcvARCyPZ0CtG+64iS4qxsecuOS6+IP29nc\\\\\\\\\\\\\\\/aS6h8tOjzhuTUFTQIHtBMY\\\\\\\\\\\\\\\/fSpiF2igXGBmO7Pczx6+ZlX5W7\\\\\\\\\\\\\\\/4\\\\\\\\\\\\\\\/+cXtt0Xuu\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/uQ+w6NVBhe+1m3jTMeTGP5E3ACQuZjEGzQuGu4F51+kbi8GS29KnLWAOAOvXAGJ0uxbvvoX7WxcNqsB9dhhxZbRMr\\\\\\\\\\\\\\\/yCW8Jh1v+ccwIdQwvwEbqLMkQAUX6iQyp6wSS18lxceWjFo4lt9iqBk95G8I2rH20Qgk6sM2FnpDRmBkNBRzvijK\\\\\\\\\\\\\\\/yO5qkqc0h0I9rVb3W9puynvnOR5gvdnRoZFk3wNtvaUIRA1MPUTl4lUtbIrNkkaXCyvx\\\\\\\\\\\\\\\/3ASSsbLurlpXFRz++xPiNqChDktf\\\\\\\\\\\\\\\/piCmRkx78Kj9DQC3QZCr6WjiM27VV\\\\\\\\\\\\\\\/RSMCCDZL0nKOFV1a3PEIZg3J+cZWnMXHU7i38xM6bmnnEfcoAwwaEsIWfOYTEpSS9MVg4\\\\\\\\\\\\\\\/vWpl837Qwb648v7WnilGKxv32Z4PWh2Y1bsavhLCZgLmGXHKwCynbeC\\\\\\\\\\\\\\\/EQVSvoFkhO\\\\\\\\\\\\\\\/n\\\\\\\\\\\\\\\/hdBN3NmBV+zstDyYk92de0L0ez4NeoTBhtECWMR85EZwvAXebQYFAetaKd1TqlxJX6mpi43Uh9ebRBjoUV0qgH8V\\\\\\\\\\\\\\\/LTzmj24qC1OLYp9lePCghWiuCoEBF\\\\\\\\\\\\\\\/onFh7Kwo1myDCobrnqVRp\\\\\\\\\\\\\\\/RLnmCZ5vNZW5oYgdvszu7WFp4gquNUH7facwQmREi0Ji7qhFVSkN49wbEqB78WMeiJDIk1DGaKkt+iRHK\\\\\\\\\\\\\\\/HNZ8eln28o8N6Egxdz4DbnN4Pjkh+ta5q2SwjwNnYT8\\\\\\\\\\\\\\\/AJ4NKSKlB8nIhvqAoEfMUvVreFzgHVghu+dOt55Ulpz481p9g\\\\\\\\\\\\\\\/RC+I8JobI\\\\\\\\\\\\\\\/uLdWgN3pIhgT6W8oxZAnjd06bsIusaXxl3Lihm0Xh2p0IsDoxgLnT8BaqnJBH6V5y\\\\\\\\\\\\\\\/LrRPDgjtQsCg1JOLSKyqve5xgyesxJ9InTEA\\\\\\\\\\\\\\\/FAMcHBSPDU3T+LEPI6a185eroaBNODq2cIwRjScedbTOagemiWdNIFBAP9EA4hqIWAJgPoTKgXbEpjNxFd5WjehBAxXOl2MSYHJJdSaswvijhf38FpYKKfQLPo6Fn\\\\\\\\\\\\\\\/rlSSduEWSEQdaDs01KINW\\\\\\\\\\\\\\\/HrvESroFHmUtd5v69Q4E6xWQdhOe8zpNhwq7eU6ggPleSagOrdvXYrM2RXoeft\\\\\\\\\\\\\\\/bxDeEc0sfe9s2tVXC9VkW7aKrYaUvqvRRH1PRAV18qmZgHQZ21x7g3Un2XLx9yjNT7A1es1rGsOnijsn7dS7fmhiW3cwA67F77vRcoJjnhuimUzHxqOPPsAXWDEmHg\\\\\\\\\\\\\\\/w093i20BMT2aB4GJrtSqTqF1ma5B22PD3lGmfip5gpZLnWr2y3iUm6Nsb9yrfs9ngaU68Dq8\\\\\\\\\\\\\\\/jsmSySpUEKAJYz3mb4JR7CmMX32DZrDqUHVz6fJLj1kxhzQnVKZrqIF+y+tQn4r4L0JZfZQmNAwbq9ad9FzZIPWJ0cOHTkA6ZIw2Fsh3laCxuqjQW7j3uUJyjWHuwuWcueyohwTtOhtR0CJBz\\\\\\\\\\\\\\\/WqNvffb5\\\\\\\\\\\\\\\/NzWACujISEj5hJ50sM4Cxg8R2b+2GD4QR9C7d\\\\\\\\\\\\\\\/kZwmsmJqi8df0u71F03TpkAZdBwii9EElMoFmhNORQKhHnzBUeyiVkngZAqnAsMkooOMTCguKWHUDVL1LsQexkH0jpJW2P6ZG6N4kZMZNYHEymq4gZY6cOGgdibOwmq6k5AtdaE1yxRJ8MdFnUliQl90wx1Jj\\\\\\\\\\\\\\\/gqUJ6Sb8ZbbCNM\\\\\\\\\\\\\\\/TZxtecj0MnD1QiDaSBoVIqHx2L97OtyKu8amnX9Ki\\\\\\\\\\\\\\\/GgCmidegnEoR4hLI+VTgNxdGcXrHZdPXnnp\\\\\\\\\\\\\\\/9OmsMNNTYlZ3f4BFB61EtbFUFUtB1lHrLTliRGag7lv0o3SNsSYo4vgtT5WRJXlVpWgK5MLBuiGaSA0itSTE=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022ym3lC2610HL+bEcAlehZvQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002211311edf198a3b744c7609e4d113a192cb4d5d3074866be87e848970cd06f041\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A517.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A517.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0463\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0463\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0463\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}