{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022\\\\\\\\\\\\\\\/Cq5JoX1gRaEZfJ5qr7uGPLan8MHQ5If3aIvFHfR\\\\\\\\\\\\\\\/tDq4J7b7+TJbfWblgJrwf+SL3CoZan7nfV+\\\\\\\\\\\\\\\/GgLuLzoOh4QIcVzJw4aCn14DzicRqDhuI98t5J+b7VN6fe0Mxl0CsPN2dN7GqrkHkTj9so\\\\\\\\\\\\\\\/DPKRBAenA00f+wW\\\\\\\\\\\\\\\/Ehj+P0JjeiBX3oPDjsMMGCACgdkXmEZU\\\\\\\\\\\\\\\/ARLu8psvkXTF0U5tdaHDaoPNtNUD8eYWx4TV10NjeehD20upvg1wzVNDhHXCVxT2csSYvd9oBkP8OSaSaVyK1wycyMYHdpCdHoZKn85Og3L1DbAV6NOm7XXnIyw9Ny7w8z8+E+LkYNAPYJj4sjWYZASsAXwGUcCjW3HcB72jK2rVFAEfX47YDbmWlKITqE9KQnRvqIEGXRUOBlH7F+b3sQ9F0tUZJH\\\\\\\\\\\\\\\/Js8UZ6NCln3fvm4Qcjo72lQy8jhCpiMl7Q1c8wU\\\\\\\\\\\\\\\/zaYpMy4z0nADML8cMSIv6t41B4HlMxQLTxWmToQrCv3bgZeLCBFuTxS7BPLXJv781PzFPvWzIbNjvmWkoKIaU8jeqSGcSq48+hoOi2HVdUrsUQcdBtj25aJLYdyoqw14N1odydsYLMz8dB\\\\\\\\\\\\\\\/xkhz1DmkcDmjImlSnHhu8iteNHKhqA5AxWL54mSoUmgKMIljg2NKTzSi4cDLg5b+l6o94rAy0IEdbOCLsbsySQdBqMRnUI5utxy+BETRx6DoZUpHzJKmFfayKW5M3PXVEmv7cC6Ha2INHgbimiayMk6eJSLBeiJ6MtZttjq6Fh4DUyvqtSQk7SdiCFzT6ucvSutkDgVQsneOHHbeUby0PbvUp23AzNPb7EFjlimY2hOB6XYFtwvVfCbD\\\\\\\\\\\\\\\/GDu1y\\\\\\\\\\\\\\\/mDoF\\\\\\\\\\\\\\\/Q97w471f\\\\\\\\\\\\\\\/ybBXTdrjW8AAME6rMz0+bGyT3zlOaRKC5A6sFNjU+eo2cliGDxQyLwMRxTmrV8POGEMEY8cwnzRRl+Q4smxRPZmJFAG0IDkq\\\\\\\\\\\\\\\/IJuQsVUbXjbVTbd+XZZRJYeHQsfQCiqR0ITiLxmrOBcgdRPzNeAEMywLWSLzMgnHQie8OBXBzW7V3dFka77zjV6i0GlMX7HmHA8hhN0CaYgvsVsHNvrs7aHPSW5mX4kVHR2NJuvwdixwNY3mtDiOJMHyuOInowIt80g49in4vZYBhZRQHPy3qSdKHmyrmn8oBiHGTd\\\\\\\\\\\\\\\/laVA+R0FN7U8Z207eIqG605yhBvrNKnf9c9TkDXt9LmRu8flSum\\\\\\\\\\\\\\\/P\\\\\\\\\\\\\\\/TRFNU2zWpmXAuAWf25Z17g5lroO6yvAcL+GCJ8d+4ZaUm87JpPBdqNyLdqsQeMFA2soSBU1dx1SMivloBnpiapcWXotX2y\\\\\\\\\\\\\\\/c4enhdgAH94aPG274CdsbNr8ofw1g8x3Cfc7MF\\\\\\\\\\\\\\\/eWR\\\\\\\\\\\\\\\/FxSGqyj2JD+LgAJQn1qG6J4y\\\\\\\\\\\\\\\/bPoVPqOy0GQ1hfCXPLwmW4oIL3A5KBZyXCOIM1\\\\\\\\\\\\\\\/bQcKGtJ1V4NQ0iT2VIW\\\\\\\\\\\\\\\/k+6v6ujAWUiBxxzftoexSPqMqPT3eSaM6lZW+JIi0prIV3YJ1YQvPRwVlQbbhnrpDVaJjxLcrX7zuXXIEcj3g2lZV3E6xoqceCt\\\\\\\\\\\\\\\/d2IZuz7z3e7b87UPgHHeEkKl0Lt1+fB\\\\\\\\\\\\\\\/EgNabf3Mxlo7gsKB2GQqUNc\\\\\\\\\\\\\\\/0HMLFM1mXIXvOsV8uIYmAP93Thr9oTBW8UeecLw5IyN9\\\\\\\\\\\\\\\/fnCX6LYsU5SaphYUJWfxI3qX6a3Zc9urzImL4TRTEtDARw4HJ5UWwTsEhMy1+Xzq7fgjGlIvH90h41qPeP0VaHLK3dvgwEEMJVJcfcEwyZHoXnfVag9\\\\\\\\\\\\\\\/RuGV2NGoZCwgDTQHSODRnomJenx6UuecEjvyW\\\\\\\\\\\\\\\/VrSd13rS\\\\\\\\\\\\\\\/IMhZpotL3+S+sKg6CAxKJ7H3WLGVrenIbcRvrYSqvORlZVgojsnBOPmTXmwfpSCAX1Qpjhq80tDIqnfP0ajB7NE6ftvjl3hHXeLCyftLlxo0kPXxcTBV5b\\\\\\\\\\\\\\\/0rLoyAJMR3ROUYEsGmlZs7B04bp\\\\\\\\\\\\\\\/t7ZY9ftxbyM5H9ZHkdTRz5uejbNpFxEkfHazGQpxpMAwGz988Iz7xRQBll+\\\\\\\\\\\\\\\/SV7V5HcfwL6RzZ3zGthCh4d04f1gk3AGE5wFTuy0CSKl9sCS9y2wTMVx1fQ1tYB5U0mgl2iagDITZobDTAhGwTd9gMQ14v9rbYFqkMZ4QAFqgw3JA8l9RfvP8UWzT60We8YKy6GiKBiiyGlvF59LzPivoTILvTWFx2x+sXLKEc3\\\\\\\\\\\\\\\/IZdeWT1mGqGaTzMclRrFhsTgx3goaPTVVa3dxBF\\\\\\\\\\\\\\\/z\\\\\\\\\\\\\\\/ZV9JUpq8C+yNGePfrnZ31LIbUH1uZIPlm3rzrmx4XALpCsOtwdXBzlo\\\\\\\\\\\\\\\/K+L\\\\\\\\\\\\\\\/aloVFsvbHFqidvPbxezbckD5aCnxfHFzW5xPcjqDd7j6L+obxOS79cPbh+eUFZspFwUwuLovO3iQjEVz5w+zIK5DB\\\\\\\\\\\\\\\/UIRrtKgxvgRkhP7bPw6cf9ILyItKPScDHJPmNxH3j4x4xU4MDWIns2M7CR8yhRyoEt34zlbcQPvt1YZ7DwxtTAexBPLkXbU1yuvFVZFUmSqZigfqdLdrWzr3y1Q7OlsVFiz5OXIFBmfLqWqV\\\\\\\\\\\\\\\/8g4tp4VxARwPsf18w4jz8gNIf9iyx+j1eL1Z8Rdcr4B9lkUQHXzB96enNIrETppTMSzoHu6qdb1VGkU=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u00226fra1p6uvLcc6P+4B3sg3Q==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022df2ae62e4239df34c35f88a2d6e7b7defc29c2fb446ec9a7fb5439052dc0734d\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A977.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A977.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0877\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0877\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0877\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}