{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022n1W3t+r8kB+GhmcY0OI6TdjOJA6gc+zg255t8rO+hCt8QCOhYkI94M+7Qb6dFyyzBSUKPIxJ0WFisDWAgpN0lfn2lbKRCm0uRSiRJmplt2zHr3ysj8ao9RqS0RnP8TWMWId4IjGJCyE\\\\\\\\\\\\\\\/8Y7+R8AnTQxPmRRTX6Ema5HZxwdT4vUTXCrJpRd7VPYqedrL9BO3EVrcB7b6SNVzn44YAeafG\\\\\\\\\\\\\\\/WHfF55+rKttUbJfG\\\\\\\\\\\\\\\/BfgghYbPUsfWcsAhu2izZJVnhmnIkAPgrGNc5\\\\\\\\\\\\\\\/+Fuh6B12v8eWxF0N3GEDHQ\\\\\\\\\\\\\\\/jmSF5YiDGZh9ntR3qiRmUKrKi8KfaQpLB8nQJyuyy43epnAf1pGAOdXChLw6xbZJBh06I0KPhvndIL62PSAaIDwfJ57kLyyn2tapV7YoNZngfx5P32mdLhEj3inUiatR+Dk8vTuLuu8XbdG\\\\\\\\\\\\\\\/z8KrOEy0zIIZ98uoFwUQ2RxmppjPPVbpg\\\\\\\\\\\\\\\/UOEmHJbvd\\\\\\\\\\\\\\\/ZkkruNnlE6HSafiCLVmrVBk8uNkCjOdzhb5rvagfKYAf6u2RQQmpKda7qlMmxkkG7q9AI5fz1BZYBh0xrfiFGum837xzsk6OGQxP9hp8mowcWxzZrVr5p63DjcWXfSk1FrRNb9btdrgXm7adY02cS5JjMM1JmXv\\\\\\\\\\\\\\\/8UgtffM0NYeLTutNaum+TA3AFRJnPEe2ORnOosgAxaGJyiJoW9dsPf8R+n4NEN4lO4oEu1tHS3p2q4Mf6N2F8O5u2hKqYL+4VVyDGhocgm2lOMzxmE5gW2wZM1iwk07qkt25BTTXEs\\\\\\\\\\\\\\\/NLwn8GTsLvO087RyX3BqHbLxEARggEWiCYqzY32UDWXNYlA+lzjXks\\\\\\\\\\\\\\\/jGvewNZtZOlWv7twxygFQvY1npAjq4Bf0EcMDHSmwCyTpXlpLTmU1kfa7Hb7d0uEce7DnKgDOsGxoAGKKJillaqX9NXZnB9GI8wKX3EF8\\\\\\\\\\\\\\\/J04kaCFpk9FyoNR\\\\\\\\\\\\\\\/LRI+HgQG1wXwAPcVS2CAxrhEcbYQJtsN7J0RleWY2tDdjJFulLfQUDXHUV0kyu7NjOUoF8PlGfISSj6ZP\\\\\\\\\\\\\\\/C9HxosvUeWfappRGFnbjEf3kMmhtqS3wL55RAu3xP86HI2kGcKx8gf43q9eDU248JTbvdA2qEMNDjaKGvR\\\\\\\\\\\\\\\/TLOqo0TwLm5K02bqhhabD9ddlUzb8XOcQnsMPPCVfHNJ3\\\\\\\\\\\\\\\/J36PT5Mh5m+3008mekh9O7kNv9auD9lS8m1K4Q8wJfq8GfyDRDqPLr0Y+MTTGwjcRdFRKzA\\\\\\\\\\\\\\\/AEmOfmTtsPHAVXqQLBxFKmd8uupRMI85VxgKkOowvOAiDUNrXzmCTwBQ13fxgV2EsUn3z3SMez6mXtEFu3zbaSI18qMLzQ7IrKdoK1j5jmmOBmJWK8p0s5RbUO7WdcHcxVGiHDMVsN7EKBi+jRamv91dVcHkrVb7WywabDePVIP8fz63VohsqAWEoX7jIDiJarKoFYJVDs\\\\\\\\\\\\\\\/EwKHUbV4JorMcbKaob5DYlN0vVuLuqi3Twb6p5i8xvcT+YHJ\\\\\\\\\\\\\\\/BcoNTCef3JT2rei33riH7gaP+2JOP2dWExz\\\\\\\\\\\\\\\/85dDgOSodPxKDOEkioRkiCzyVAq45XrkUqTYP\\\\\\\\\\\\\\\/QR61mFHWrqRE6FsAvSQ7aKfjdB38v8hYuogCZHKJ8qnmZ0XT8If1TjDoSlz3QBI1GTGUg+64lDBca3+h4s9k1D42Tsc0jRTSE1H3BqFMKBkcJw8feNeQe3lIh2JHzKi6deSZiS8lNynIWH2PQy2Z00sdrFx\\\\\\\\\\\\\\\/M0qo+bLGgLXBfpmDoQH267dxe2znReIxbixynq\\\\\\\\\\\\\\\/GTEJjIQXiYD9L3eszwnJwCW4dD0\\\\\\\\\\\\\\\/z7SCcy2B1FExDECLN2c3EG7QtTil+cAvlpkB+QvAdQHRZZyJwEqXnakikj5FXJhB9y+36mkf9VDJ6dAkQYwmp2K0Ap8H6G1r7lpKovW0y9Yzk9W9dx6\\\\\\\\\\\\\\\/AI7RGkMYut4PoMGdqZjZVJIXTSYXaEVV27SUtRGYzNVSODZ5aarI+RKQwHBUdSwJ4lbEbMrAP4B4vUJ49jrtNIeEQpjzmuaEFmNnsCZKGqVNRvtFPC\\\\\\\\\\\\\\\/HAfKQbH6cy7E4E\\\\\\\\\\\\\\\/L+WOgQbg7rNFW2uH2FXF3IDrDFhsXVBTmYukjoBec+rm9cMB+lDJuiKigR3sLytN8UdXk5\\\\\\\\\\\\\\\/w34uKiCSItchEbmLVsIBneY5RLSOxwlFjKj7KMJW2P9Xxs5562AsBPeo3eZQscuJqsugfMCkgXsy8NlGHbh3cUUDZ+ES\\\\\\\\\\\\\\\/SpG1jH13Yoqk6rpVHHLRZ9\\\\\\\\\\\\\\\/q9JcBDLEiN2ENv1mmNZ1WMf\\\\\\\\\\\\\\\/T8sp8zm6cnnue6tNeJ8TyXAi70PNFfXHVWkDJCXcs5KKvB59nH1KqvABgLNeN\\\\\\\\\\\\\\\/IyPNGLmnu\\\\\\\\\\\\\\\/tX2HaSpvQSUQef9MRTTXpB8jhlO1MvfdlSE6y4i2X2boZPu+z41TlHADQz2dsqreryf21LE5PATaaOWzhMGp8NBfMZbDO3UuYp\\\\\\\\\\\\\\\/rDEEVX9jDEOdsO3TF0C3qfbL9rOzCynqRPE59g+dtLpeaXootKbzTxHiAmsxqbhGGc\\\\\\\\\\\\\\\/nUCNj8baFMQi8BQqObPtydGUqBiMeVNMIIPz7McvElG\\\\\\\\\\\\\\\/B+pCVXMb6neKjGntJct0znRknMp98Ny6NPG\\\\\\\\\\\\\\\/p9GIrzRlztXh60Y2oZyo0\\\\\\\\\\\\\\\/+gmx7826VPpIIL\\\\\\\\\\\\\\\/+lM=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022RtaxjzOa4jmoNGbRHPceHQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022e6730eac67231d7ce4e4235892d873062d8a19d05e1e9d2bb31f9b1778a41593\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1341.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1341.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1216\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1216\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1216\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}