{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u00221tYY6Kdhzvfz1DlJ+Zrsau5ndhrpLuIVa4fEtu7dU65\\\\\\\\\\\\\\\/T6TX4aGl04pYTni0wp7SObBTr8XvXMlcCYXy1ceTI5GoQuFmlFIo3828LuCf812YBC6eQN9kLO7fRpV93mtwlk7hGgFXf4aqstF82Y0uvytQpo+3VqUGBgm+fqTzAiIgTAGrBhqvA9jhDS9ZiW58cIfGoNtVUTCQgnXkv+YgauTd8mx7d06wH8lYzh7FlT1rWi2zfWVTFirR\\\\\\\\\\\\\\\/LUqpK5DIzmk0ExNwk3t27cPUhg\\\\\\\\\\\\\\\/pZ12iOa4Vc9ALycP0VYli1TbhlYDWV+RISRNrj+AmwchSwYqvQza3rbQ2sfJTVSqz+s0+s5YxMsnhe0cUr2Hx2p+peEVM6\\\\\\\\\\\\\\\/T92cJtfm6yDUpOw9qxf60YJV4+tWWrthImFxfo383V97YmdMD\\\\\\\\\\\\\\\/dkAqSxtcMPPWs6d6M7lZlq3O9n0g4QLso1yD7KH6j\\\\\\\\\\\\\\\/UFeQ1TpX+Bvjn7l\\\\\\\\\\\\\\\/1xDO5iFqcdRC\\\\\\\\\\\\\\\/9dmhb5DhGSPdqVELVYApxX7bYQpgQ9eYsjplM8NIN4kw8mbtpPZOmFL7eFvfgT2t1LaHw7zxAH\\\\\\\\\\\\\\\/jrI1MggJAKCLgcON8iznH0uGuzQNsP7nmGgKIuCdAREXKiZrokVuPtpdExEY\\\\\\\\\\\\\\\/AT5R1Oy0RVi6gJZ4Nhwef19ewDn9KBS+D8er2FqivW2Rftkx7y0XLyRd3Tuq348z\\\\\\\\\\\\\\\/fgmQmj8X01I6svLWS53uJCLMi+2vUj1C2PSr0ngeB7kn6CFlxpkK1jdGyk4EnNTbtMmd0ly225yJjiAo\\\\\\\\\\\\\\\/6lLh7PzAoNBKaEooG8YTy8m2Vyp3pVc0eDI1LSbeQCwxRBhc6PWdvuHkTADxXyAEtJ53qcyLobMSGRVB5w5QQfkwiBNP4cFpgc\\\\\\\\\\\\\\\/uDLJcwPbhb3m9mRSdBb\\\\\\\\\\\\\\\/34BHGhHo9Hn2HdXk7oFMLAms\\\\\\\\\\\\\\\/oW3ihhD8s3zBrhZzTqnJtz3O6SABXOSEqGl2TW37Yb+Q1zBRwQzBJwQnEKhRYTCmJA7TSilINr9uhFyAhC5WocF11tpXcrHrJKQZaFGkAud+mTHX5RRDhdnp\\\\\\\\\\\\\\\/UG4IsFxbsykMsun6SiY9Dvmb05qGe97IliQl5W3XRBxeTbXAxsHPnrl1k6AuIEpy1sw7mjSAnDgp0ed4MiY+EHH5g7wyTw\\\\\\\\\\\\\\\/DxlIirulqIC4gYkzQyhCLFTtuWSijReIJv8rUDQTCc+8to4hNMTPKWpHsSnqHSwqKyi4EmxIUiMH57a\\\\\\\\\\\\\\\/sXdf9\\\\\\\\\\\\\\\/tN6Xms\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/VlAV\\\\\\\\\\\\\\\/NY4J0hW6IjQgiYNQWJcKrWu2gy\\\\\\\\\\\\\\\/J1KLxck\\\\\\\\\\\\\\\/ibiV0D\\\\\\\\\\\\\\\/miotOGupS8ZVVX17WgblJ6Y3DGwKXWoEqBPzQ\\\\\\\\\\\\\\\/zZlTiV8Zk8bgYPYWHiIKYgsfnKZIjeiQVCeUXXrIb77uPi4pWm9Ut3VHnqnFw93gCNTzdZto7g13roND6QBTiQM2EQfqysC9CG5p1hG15aNvc0CnoPzCqDdwuOGOkLaEro4bvYu5n3rEFtETGz7oz+NfxMRZ4RgE70lufKMuwBi32000R55Xvx1Wd4K0w7UE64DvAcQ9MjxehVXIp4k+ayFMUbUBre83n438nmK+Hnx9K6e\\\\\\\\\\\\\\\/GBOT33Sd8obQzybiW5kQfPMv\\\\\\\\\\\\\\\/d1IjKUZk6yNSwyPLW86mM6AB92K8YLQcv0EjKufdVuFA5v4pxdwWETa0g2W6T\\\\\\\\\\\\\\\/TgJwtHaX28QZVLit4aD3Zav959pvH7xJXUTXAq0n1K8bw+6+3hu+nxwnxMh8csvNremlYU7TeuyWxNA1C0aNeVVhs\\\\\\\\\\\\\\\/FZ\\\\\\\\\\\\\\\/fDeHY8nMhFy98zHksZattt+2aiszcbsLOHC3QpzywJaVFK9Rd6panMdB9kH3nVlFJOInOy5IDgwvk7B5O2QEUSGBQQ9\\\\\\\\\\\\\\\/1MhtGLgrMKlZbxA\\\\\\\\\\\\\\\/acNC0jAS0VyMnRLEkFtmK9fzB3AVad2lIICLmYRQTywl+chlCjHbqnMjFpu83Ek\\\\\\\\\\\\\\\/28D\\\\\\\\\\\\\\\/0Ye4hN+OI1MxvWcQlTOTDHDUgWS+Q2msw9jqFRghK53PIYDOUMCfJTDcCOC0VYDE4bTqRWePgZZ8Ys6TZ4DgbNS2sHpZ6GbAft\\\\\\\\\\\\\\\/reKM1Jh1aNRedV7PUAy1AJOcKS318x8QD6T\\\\\\\\\\\\\\\/+8h19bjh4xUQT1APswvg4rBOy\\\\\\\\\\\\\\\/jReAH+o8w+R0USx7lrxYM3loCoV7cwAMdh2ubzlZyrkWnuOkVEM+3D80RedXsQfUjKGDPyxxJapkTs8xsRk1erRFcM2eUerZmpweTAyGE0Yt85c2HjUlLhM6C1AZYxnPa02O4zg3DDijLk7erBHHPoCeRWhFrOMPBIClubOz9SdqMjU9XRj2\\\\\\\\\\\\\\\/2eUsYsa2aNkQBGO1V5FjHjoVWXOW0heODpZyWWQlyk5ASYJkswimljeI4Y1gqbpIJetukFvmRX8sul1a0QJWXDO2krhb6SnUbIjQ+6vT9oz0pJ2oCtodP0CGK37cUCI89g3Yd\\\\\\\\\\\\\\\/ynK9rRI+y0NCLv2Wu2IJwgymYs0\\\\\\\\\\\\\\\/3iTdz8yCLE3dwuDNJjvzpLiMBqTE0qBChsvfb4nOfTfYDC7ibdZ23yur0ByuihLojFraxIeyV\\\\\\\\\\\\\\\/2H5y1NaIE2MhNqrbASLzTo2UcZiw8VkmjhA0MEB\\\\\\\\\\\\\\\/0YooJ8UXjouGCev2eozcsPGaonGBh6oo5S+GI7Jd1kzr3zuHpbtKAMvLPtETqPsyMVWD3e5Z9yTU=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022pQaCGm66eKPHtc14PPcVew==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00227dfefff02e561c0c1a3ee895d6293ca61e78bb05651d30173670fec338e97f0b\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A685.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A685.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0602\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0602\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0602\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}