{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022eunCD6jq8gBP5aGEe65Ddn+Hq2UJW\\\\\\\\\\\\\\\/QKw2uKlPOEpmPprDy++3si4AyWNLCsAVhhOno2brW64zKnOChZnffk0CLjRpweX+Q3BOI9ZnKcUwQdhC7xVgWBN38HYnBGdMO63O0d8uwnMpgotVLkwJsXdtbULeKaanTZnB4cmRH\\\\\\\\\\\\\\\/OlaMiPPZ3GQZOmN+0Dxt\\\\\\\\\\\\\\\/MnhVChd1UUdJGYDxS4W\\\\\\\\\\\\\\\/bqCm5AkQyzDepr9OF2ErgI1bef0oQn354wWB54ht+BbrrBFMczEVVFz7UZgYadukPiKkv\\\\\\\\\\\\\\\/BjBTUIMdPnWr0N8pjKIkMPVlrM6fgoMCaFIdIyViEmhXSX28kgw5xrxlelDsUb1BqXAD\\\\\\\\\\\\\\\/3\\\\\\\\\\\\\\\/zAZjnuCRB5nM\\\\\\\\\\\\\\\/jY2hncJ5ofb9yJFk8DfdWEFh3mFmbNLM9MKOlhsEt2\\\\\\\\\\\\\\\/IOdsjEp0+SJiU\\\\\\\\\\\\\\\/KlMAAfoFceKX8gtQsrtxFGmnKEvZwUdGpJ62kVB6hN\\\\\\\\\\\\\\\/6xlllczkx2xSH2m\\\\\\\\\\\\\\\/V7GS1lgXTD6kUn0ZQ9iaR9yoQ0DQJky2v1JcJO7AFdfgT2iU3StlU6rh6RuoAwvewBu7+1LZjpFksBwdO1LoCAdo9c0UFvXdDkaNiK7gREIZ35Z35+UIJAxqR4cHb58NyIlEh4BqnoVefzdY78zMeKy\\\\\\\\\\\\\\\/uYIz1L3pZtvwq1aecOMmQ4vneEgdu95TWgKAcYrxcPx3R6PBd7h0r+URBV9t2Foo8S3Cn2TbZld0NUfQQSfbKk1xb1kd1Czf823zOGIta190bBn+Js\\\\\\\\\\\\\\\/BhLox2oWNTAORTRf6a1Lh7+DHHRJrF73ARjwjYv1G7v7pXHH1Om7cxaNQXUj7CV5PBltgge2O2Eh6euPDOx0zcGwMrmmWPcOvHo65e93hTUD1cXM6nRmKkrF87iPTNu6dbYu3d4yDHUZAvfiHMC1xaNKx7ZcU1YKQ7XA3iXCkokpuDMqGU7gz0PTqdXB9jsAyEwbEW36mmogmSkSg8mQcjxKYNZKwqCDv5QrGKZnCu+OnOKJIcoxbTq7XbkthdgshnxAjNVK+dKMlnVwxKZ2Wetp3tZVSqIO4mpN\\\\\\\\\\\\\\\/o3BQfBY9h0mNNhipXsf\\\\\\\\\\\\\\\/eNICSGlKMYZlVib+ZxNs6dGy8EnPScWq7sYvajPK4w4SdZEyxQn9FxyxMFeX0KZ6PmtN9L2m4mnbjh2jTMJUv3wXI1bbrbfxC6vkA\\\\\\\\\\\\\\\/RLGb5uITCjEr1BwbdU3TZ3siNSHbxT8adDm7Y5e+GDL+r3Wl2IIldo90lp8cSJuTREWXt3np9QkQQBKmojArv+X3wWMNnV83x2cy0xGrVVrZ0CNCZ7qldGXWPDzttQlS5OWTnxSn9yRNmeDwBe67ahjTp0MWX3bZOjS8OT20CAHFSZChux2uy7j8Dr\\\\\\\\\\\\\\\/F8WzjJEQv1RCubbwYpshvQKSYw0fkRCYqk3DDBLMDB\\\\\\\\\\\\\\\/spQnru1YA0HWWLW99sf8sEY4vl1fOIeD69Y6Fa2AF2gkdfW+DnwQdzjahojNFAdNlS2TQtPTxzGp3ngAU+iylu82gWoQ1rq+r2OdRf9ohRIwvvmKuL+fVfK\\\\\\\\\\\\\\\/F6yepOb+GxRFKUpv0bfCzTyd0BPZkk9b\\\\\\\\\\\\\\\/k072FESbuDD5i8oZFa3lMAJlg+9\\\\\\\\\\\\\\\/w9lypdi1p3D28ICW8LawSQDHoLyTjggkf7jGxaPoevgt0Xie4VMQ11RshEUV5E8EFgkX\\\\\\\\\\\\\\\/K4JeoKaJsnlWdWIyOV4bWZH4RHfmYNh2Bh+M+Gt\\\\\\\\\\\\\\\/41E9fdOmnGyH+5ka8RhUiqnEbXaCgY\\\\\\\\\\\\\\\/6\\\\\\\\\\\\\\\/5vew\\\\\\\\\\\\\\\/ORTMrIPhNaxuvQefFX6E3hWjJj2PL4qmLMMgE0Ceg8T79GZEkvSiT\\\\\\\\\\\\\\\/raTET2\\\\\\\\\\\\\\\/m8yijG2jcBddYyGA6pxeJxBIiYmug5dMKBX\\\\\\\\\\\\\\\/VK8YxfJllqEj9DcQxfbGHOsPzaGwNF0BC4PPSOMPPcQ\\\\\\\\\\\\\\\/lQVAIj371oZMify1lIAKe+iWcYyoPJelbYzZRkfnXPIbjvMyYlVwk3cM34b2VfXYlY2onYl2QjuSG23Ax55XkZGtByMIPOjhq48B0Yo2ykC2cAtGjvuo6GyZDYsfkakakSIMZ7cbsGkyx+fsGqt+5XXbaC5Zeu0nROdRCaCII+BYC+7a9qg7XyoPeHYmdyTS+6MVuSY\\\\\\\\\\\\\\\/Ok756KOPmWaRb6gogZ5lFs4Jz1FO4VzpVrneXZ8rUQMLA4zF0lRIt59ALQ8QxZGYNQdnd311L9z3oUxQ8+enGEVpqxP0CHSwkYaVWIX80xpntnuvg4QisiHliHVayYjUO\\\\\\\\\\\\\\\/QcAytz2kvutx\\\\\\\\\\\\\\\/zvUtGxRKazW1KJC1n1buxQMtsHX9IF6t+wn5t\\\\\\\\\\\\\\\/xaJnCvIBisG8M7SbnAkgplUmHUPhUQyBPVDu3RnrH2mE77bJRsR3\\\\\\\\\\\\\\\/UZr6blDsXKqgAKTjZ+OzG\\\\\\\\\\\\\\\/s0JmF8uvCnDG1marKYEoXzZ1IVxHre0ROgHAcmLj\\\\\\\\\\\\\\\/fvymCGd5IDYKz7HEnZ5AlStDRMRNjvrci\\\\\\\\\\\\\\\/4p3j4S9By1HxkNeDo+sz\\\\\\\\\\\\\\\/isBjgyQ0cTsgWA51Dxk0ZAJ2C7QRZptH7GOoGUVvykdg8J5NcOC58pGx8xitKSCvL+aZwkqi4\\\\\\\\\\\\\\\/snxf0KU9ZbOsv1NYgmhBAwtXU5GND3s\\\\\\\\\\\\\\\/bqCQCg+Fv5fMxPMzs+AYSOLIdjre7sSlBgn7OKox7u\\\\\\\\\\\\\\\/haqTdU4zhVJFGZ5rWJCBTv0\\\\\\\\\\\\\\\/8ywreB7FJWQxBRJgmA=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022ujom0HwOpEfg+y5K1lx+hg==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022a8d2cd45b6b1d34fb30bdf770cfc8fa3fc2de8c8825321ed356c138008ae585d\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1368.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1368.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1240\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1240\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1240\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}