{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u00228J4Hn4XwLH1p4ytR6s469U46lhX6DwAqP9KotYbo3YtVcZQolGXVQKsKvUrbDdlJmT0hHxJ0IgG65LV\\\\\\\\\\\\\\\/TaVmPT5dWRxntPEm1HNtBTT4NuCgqOLzLftFdHXfgINos8ZRliRJsrvpSyNkEfIOfCj9Ct7C0Yhzod9aJVDbIxB6Q1V7R+eVQC6PYPfNrjAP6QJ7+eImbELXmpYlu+VeUFoeIlYPleUCBkGUOoBDaxolyuI0vE4i1qc8X40CA5vbZLHqZOKbptjnYDdVW06NKEMgN7iNnHoCzWs9ZCs0EPcXYKMgLjdhvgBNhqN\\\\\\\\\\\\\\\/STWqos1H9lopij77bO0aGg9ukHoGurcKGcTpv3nr\\\\\\\\\\\\\\\/1yxUjYuCd7yHBXIWBPXnxwWpfroQ3s5FJo1CPqrwzh\\\\\\\\\\\\\\\/3XuUoXrxNTEFGiFGcg86kviBLmdk+g6dWUPGk++E+iwDdpU\\\\\\\\\\\\\\\/Zgjc\\\\\\\\\\\\\\\/gm0CVuRf5ThIXbqKcDHQjrw5FMuMfKuY6bckDdEubPkabD0JSusV9LWEBEGQ2eJrKQjtdz0+XYCWPZv3bitgfIezZhcHIPLpja512tlI6\\\\\\\\\\\\\\\/qW7LJg6jye1WqoQzo8mc3i9YYvu4oiwKEseNJJgmJntYbCH0OLJAorh5wyE\\\\\\\\\\\\\\\/SexeDwzxix5c4McTk48qAXZfV1Rt8j7qbBhV7hpvtTN\\\\\\\\\\\\\\\/kemsxg4DE8Pe5B82YOmco7qet6KT02i7GlXV55+KWTh74JKPkijedfspDbKgCz2Ox85sD3ouKjW1t8RK43bRwRLylIKU1PdCRGqpvUQnikY7NXiiIWGtGPi4KwNj6tHSCP+DFr8vlCUt7zcfil72ioRu\\\\\\\\\\\\\\\/BpO\\\\\\\\\\\\\\\/+ZHFLJdHGnDBopkMB6jjwbCW5uLhvPNS8jn0gcQ+e1mXX7fAvkn8VMreHKa3kw3N+oUCNWgbAhtxaUY89joxR4fr8PO1dbOyMhzzvv+swmLMp6x0v9pcrkwQSiuS4Mde3gK3Cog\\\\\\\\\\\\\\\/niy4JjDz4RLMJkGbAyWmBHyCZ8tR78k3ueaw0Bc6RK5cyoGmuzc62MEkkIvbBxpyHEmI\\\\\\\\\\\\\\\/CIbsiI0nSS6Ks9aN3GSlu7E+58WuzGry8hfneFewgCv7s+djhn7FachTWyhctvzVjvPN++KYr6m52L2VBiwVlqnhAvWzTUdE2azAOlHp\\\\\\\\\\\\\\\/OjjI7RWsWrJbdw7L+G\\\\\\\\\\\\\\\/OhBmSWas8iIfFICUrOTYcO2ZG11Yan1htVpILMZyYaEH0oo8Zk3ZsjEW8CM8QqchqR2FTqDefjyhhUZOW5KAmGWSBOhsXOqEvw0gflEC\\\\\\\\\\\\\\\/WJAO52CcAiLvBUEY+tIvaZteZwytsjU52upvMttO69Syy+mrux+nW+zmVIQIkQ1XcOUrNn4JlYQyMxzl7OpRGU4m35fM3aSrC9wtARFHM15LAb9AdZzZhl2wTOzgKmgZrWJDEsOCZhQ2cdQSoEoQ08pmYIfE7JiC3UjGEJBirI9KwXK4WJMYwoHoBGC2YNdVbI1JCEaVDH\\\\\\\\\\\\\\\/PYWsF1KyVY1A5ecBiSW4\\\\\\\\\\\\\\\/A1lZfa\\\\\\\\\\\\\\\/oKBOGTFz+OEUSG7rKAGlbOSgMwpbfIUHHf+DW9H18elXHhkAAiQ1mx0m6zMFaiLWfi\\\\\\\\\\\\\\\/iFKnTnGzl\\\\\\\\\\\\\\\/vuqXKyhzrT2eWgVZMGRWEOX75FZCndqDuEGP2j\\\\\\\\\\\\\\\/0lxFAzUeAHpD33tbVNF8Z28eKFSZ2CPaOyiiR79Ob6bcwvnYo557WboXO9ljictx\\\\\\\\\\\\\\\/8N5DpLTG2IvQxhyD1uBHUxqerrkOYqd7N8l2BgUT3gf9DJDUmEReLS64KKf1F9\\\\\\\\\\\\\\\/S+DGfDShgmdBIxeT5s8pqUnmcl\\\\\\\\\\\\\\\/NMhtyp88hhudJcQQMNbiw\\\\\\\\\\\\\\\/jM4+ASUMTXjtTyqiiSiZ2LZuYfBtShT50z\\\\\\\\\\\\\\\/lqp4\\\\\\\\\\\\\\\/DgDgg5uVqTId4dTJMzy2yzxThCsC3inYWDn1Jqpr5gnBmv6lvGa76KMkAJo7Nd4YReyl1qXJ1cGMxndJjXXe9OSXzBf3LepxDTq45lwrB2UtdW7LBhRWBeJyaGGHuVqPi32dZ2SPdPeQTs84oZ50f9XPEdROgMUBncJkW8eEDh\\\\\\\\\\\\\\\/SGoSsRetXHokMZedobYuZajIkZMU6UoaWogbdGeNNFGPa+ILRGBmAoye\\\\\\\\\\\\\\\/c1vpEpmomeYlRyIe95Q2S3MJayMcEu+BGqu9+w6o7BrXG3WviSQ72q88vxjIfBEPnNm79i8u5GrTaXuj1Xv6voWVi5PXzxKwG+aQ6t9NQUWVZFhAcGFVpkmUe9q+CzR56okZbvKiBlHjo+khAlZg85IKgENFneLHQTeM0NgA3YOVooKWtsAoVBKH\\\\\\\\\\\\\\\/cuMGfz5fGPa3yQs2vZpdujyfu7gNASfik8CXtAOfSJoY8Kuw1Q1fOgbbcD8dYxvOeiRcW8e8BLjGqXcAjMgwWdDhXCqH0E2lPzIkmsDS+NRRCOrNawIaQOxMYvjdKBV2nGzjShw3aE5FPFrEqKWMAP1EGNW\\\\\\\\\\\\\\\/1FIYkEEjVhJ0gHe5g8S5PaXjcC8Nh4DYjfLIXj76NK2b0xgurhsq5p3\\\\\\\\\\\\\\\/LKW2JofIIWWHTe0HBGjhWHMblgMer2Eh9WFR1NgVuPflU4bXbFSA1CmVDLIx0zDs4lch8VVueLQr6ECAsXRxzlgLFa0oyUKFGciMTB0\\\\\\\\\\\\\\\/URbTMRt5BbOQKy6WDNr6FssX12+v45EZzLWqkr5jXPdBRPPkjp77rAqPQPMU=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022xfWP\\\\\\\\\\\\\\\/vQ8oB54UYH5afwYjQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00221d5338d3c46a45e21bf05935cf5dcd80610203348fab9741b5d735403a9e4e7c\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A514.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A514.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0460\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0460\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0460\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}