{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022n8vhnL41xxJyqmH2wxKInF+g7u9gWDDhEX1X8j\\\\\\\\\\\\\\\/f7aaJNpND\\\\\\\\\\\\\\\/X7+\\\\\\\\\\\\\\\/oUwpE8WNC1jPWyzhs57kXzchoM3VokdlMep437rGBMGvd+O9pw9ijhQ\\\\\\\\\\\\\\\/ZGM7kvS7Te\\\\\\\\\\\\\\\/Mg3l\\\\\\\\\\\\\\\/DloCDE0FCb7uP8hrxVkwQOoqLCU1y\\\\\\\\\\\\\\\/HpIfNqacKs1hWv70JPDWKnwQcwYuM8fVOLUbby\\\\\\\\\\\\\\\/hMTYH6suXGGaKwMWYjlSrEFoRkOIDa4SC8YWoGcmg57UlrKObj3PcqIpiHNXjVA\\\\\\\\\\\\\\\/m57QvtKbOH8BJbZwgboLUD1PJcysy+OLELbped5Z9sUQnFBtZeHr0bBjMeMYsVShIGIGf\\\\\\\\\\\\\\\/7a1GO3hJ0QkEGiROIUl8XSehZX8FC\\\\\\\\\\\\\\\/HcvE2P1nS9axP7y4m2+fwBIR1DYWMrWN7eXVzA8zS3iIZiMAsm0DIkdhOhoi30UbiBuMoMz7SEM8F+JxkKLox2vbjCnTGoB8KxF5eHcgfAPg4UK4RsmrzjEApnpl5pnTCixKbULRQvR0uxpzQYO3ST1cwKOKK2b\\\\\\\\\\\\\\\/Zq9A4QVtGi2rBXDWCBr0dc9jBFBpxucb01VUMtWZ+p26MqfT1Ik5X7+Tmdg4FjecR+cKCgQZE4imNxaGGBlmbDB4V9UkbNBaKXYYvKhBMvhN9OQZ96jQNh5Vh8JgFdbgJ4TrJUWtQJcj1M1ovdfRlaryEYT8\\\\\\\\\\\\\\\/XJHIpf3h9zfPjlIcdJrOM0uoLs+62Rzf81vGbXHKykPyESzswJTAuugvft35hylLhQmWx2skX9B9MqhloQJKzmF5k0pqNtrPTJfL75+8BmTVNvAuKB3VAP5yfL\\\\\\\\\\\\\\\/5xUCutKOPbgUzNH2VJiSvteRrgm9O+fe0f9pKFMMYKlAWiXjBP6UC1IyYHMJEjGEoDJ\\\\\\\\\\\\\\\/MnW9NRf2g6l1fxMRzFLAHG0H6Wf6u6u1dh\\\\\\\\\\\\\\\/cyt\\\\\\\\\\\\\\\/ZaeiExwIJ6bWEgqbzM9FNi27p\\\\\\\\\\\\\\\/uX+dofJub+K501mU7rMSotUiIdSrAYIuZYeEVaj2phqcJa0F5Mwt+CobVFSLKabeqIUy\\\\\\\\\\\\\\\/P5XARaYvE42PPPqrju+XheBMgHklPpztlJsHDET2Q003yu80FxKax3zUgKDUOxvXRv3u8agQhx\\\\\\\\\\\\\\\/F1mag3ai33vzAECS8NEBT1MS4Xqmh0Y3oSrzI5RZFvEM0YnpTTzDdxBOkOuViaiNIq17L\\\\\\\\\\\\\\\/dIL67i2EWw0pO5OzFxVvHJGbQ7IKdA4G7Q9q+tge7BPNvmfSqY4tw8K4rkGRdoIhGmG+o78esnUjJTZtonjGFXNKYhd96wMRzrEcC4ijrBEw2FxT4elfxOPei4oJKpaw\\\\\\\\\\\\\\\/qOn5DcLqd1fdlsPQBfDT\\\\\\\\\\\\\\\/q5Dy3+Evyw\\\\\\\\\\\\\\\/81FzPagqbUZBXE0vdYwAIANeB4BrngDb9Wsb3d48aKY7qx2ODdVEgmdX\\\\\\\\\\\\\\\/ynQRk7A8JgFei5nQ35Ys1Gdd1gVrWi5c0kP3LxEEa0oxkrfGLTELGAonQ4cYb1XOjtsUFZgIYUNW0Ek\\\\\\\\\\\\\\\/ctjmWRegbRLUcWWvT\\\\\\\\\\\\\\\/ak7e+989dhICeMZFc\\\\\\\\\\\\\\\/7fBZ79sUwoYIIsEOoWqmulz3\\\\\\\\\\\\\\\/O5HCgDoPcemG3oWrGRabJ70H59ayZhNVFQSBx0ZnLm7qNCyWfYmMrPqiJBmXKqEjAb1WsYrU0+w7sPe0BrfMufj3yknNFYypXRjSlJSDKEcNUntpvjqTW2WX6hn0BHGIi+wBaWALo72FMPsRw9CDe8x\\\\\\\\\\\\\\\/GdRm8RSRFOOzRUW9YjlZFDB661CE0TFfXWwh2N\\\\\\\\\\\\\\\/OBnaDG9joUZm1cf40+hN7cDEywsUhwCIpSB+\\\\\\\\\\\\\\\/F53tfTUKTfWa8pwUjUYb3XDSAqB7qNkXE6NYTtIaMmVYb4wNYoo1NrSxdhfN2yOvf+5foORRzmY9XVSzM5lP2ut7zsqKL6VluWS0b+NMDWBTuLpU6XAgKXx4vqlZtUDOjnkbSv2sbgk62XvUK2sQP4u5Ws2yoT8WozkMoKXo0vBfsQsGggZWhoEmdit+TB\\\\\\\\\\\\\\\/xUx6mTcpHuCNaaZPwQjEXIv\\\\\\\\\\\\\\\/Sa5q\\\\\\\\\\\\\\\/9XO7JG\\\\\\\\\\\\\\\/ZVRK5TFKmGluuVbwDFpZNXD13WoqAbFZ+RZztS1YQ1vPHXB7a2\\\\\\\\\\\\\\\/onmWn0hfoa5Z6i2GjZA+ZQlaWejibxkcWwbQtHkivOw9ksVlPY\\\\\\\\\\\\\\\/ammLqBLWSvfs9aqZXKE13drIjpQHplaoAyd8sGN52tyLvihFVwiIHk7dDzw4F\\\\\\\\\\\\\\\/rjEGWmPJJQmmCq5\\\\\\\\\\\\\\\/cXw2SsQdMC4a7TMm4J+vfodbK+WdzaDymGwA6g\\\\\\\\\\\\\\\/qFhFFAdp8bUZ\\\\\\\\\\\\\\\/G3ltye7xdYs17fB21dKtCWJAYj029tp0sv7AjYhFNWJf3uIvBXjQZO2Loo2PZh0pYSp0mWdJFvisKM1LoIEIxwY+aYKxCusX4IL+rTnLsTk22Dvu9XsG0jalD9wVvegBVm2T2SMiSn3YGgDtn9YJCXV+q6xLIdwfXZfLWz4UDBMtKAOowaTg8zLXcyN+04dr7Dsn6oxd+vjLdDG+gOl2vtyB0bxZkEFkb7\\\\\\\\\\\\\\\/mk+WZOspVPITORfap41dWKOhGqkjDfVXW9WJPRahdjvY9Wr3BTWtpqX+ov17lpTtQADVGCoruIz8Ob2DZPDOGzP7Z+dDXakKCDkjGYcK1Z\\\\\\\\\\\\\\\/H+CBy5iF1c5V7WD9G14QPd0nObPYceWg9qzLIodK1eG\\\\\\\\\\\\\\\/jhYOX\\\\\\\\\\\\\\\/1t\\\\\\\\\\\\\\\/GTxmDKI2wxiXAPNxcRj\\\\\\\\\\\\\\\/xypSA=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u00227kgBoXXR7jc2gCZqrQrQ9w==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022d916d7dd64f9072cf610990d1b0666870ecdff2e14d9d5a843f291ab4346ebfe\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1426.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1426.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1285\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1285\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1285\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}