{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022\\\\\\\\\\\\\\\/jxSvo49ASa5Nf+UAUt2842RbPaJtC91TEFLrdUAJiUBSRQnIg9VrgTKNbYorcokmeWxSePZ0oMkso2KkyBDTOncOF7FpZXVjMLYA0m1YfMAnLab3D8g5ouikFrFKs4DWA\\\\\\\\\\\\\\\/4ck4Uf7mq4\\\\\\\\\\\\\\\/oD6Q8zTrtWmntT+8lMxNr5KkgHnI48B2iispmHIA4zlFsDaCE84kJ1TDhz+aN3d5vQgrIN9VLOxq+UP+GRMZAn63bB8UKzxCI1DFk1nDEh9PwcL7wlCTY4f9zU1d1EK8oucesqiq24eL\\\\\\\\\\\\\\\/BIdkUxcAKm5tc13qkrHZHJ\\\\\\\\\\\\\\\/Hwi0wVpK6cOOIGYUlrIziS+HUjPx9XKHXMogye50Da8XAyMzyLQ2\\\\\\\\\\\\\\\/Vi5HVjw2GfAmcSo5nzLjk4dZEE3sYlOeX9TuBg\\\\\\\\\\\\\\\/KbyKN4E7TlyHDvbvg\\\\\\\\\\\\\\\/xV5lwwwHaHfg+k6TUMEZ0r92Ix0uq1bxjEFQagjxX\\\\\\\\\\\\\\\/Epx\\\\\\\\\\\\\\\/QBzIay1xAzOBXHCr++kY3MV3quB6WqSChPI8GYuLiDy1kuW1i6CnNlOUsKhI1sNDDL6uN98vG\\\\\\\\\\\\\\\/7F7M96SUUF6o5N+FTw2K+drcxTD0KFeGAFAD3ikPCfaj2aMrC1GRhZ4tZuycfUdXpZ9d10SCJMyaJsuiR6HrfWI5EI0i5u51y2tTfe1VEutbYNNyOUavDK6Dhu60R3ISjnDv4cv7t2fXxLiz\\\\\\\\\\\\\\\/ukLFpeR9cGWYtp1YV72OyHL0zDSrtWBUF8Q8eRigiuEyOY578iQj9KMQjBFg3TjLMF3p8URUGP3Tja7VBdeTARffGDwQVDz9J3BL14cRxRRUgLitN2Fruy0O0r0FSOLGDIR0T9O9vXRjQ96KHjANSLK3lus6ZeUBT+IRFUjqHtu8+zX5kg1xWWYW9EM+tXLcckh6krQsU6zl6gn7ITFfhmiOW8bJtAiUAdzwSRpfQuqk6bbW89dHEbB5O9Z4uHrIqVrCymai84iFCLqEIpM00gHvCwCfK0ls15gy1oV+3e2vb88ji7zaSfmKAVGg+BNWUQyjvki6UYfm\\\\\\\\\\\\\\\/tliwUcBO\\\\\\\\\\\\\\\/A2Z1I4UG8AKPOZWurcoEH13Udbls2IU5HRV4QEL\\\\\\\\\\\\\\\/rfGU99jSbQPudbJfglXUjRidxHJ3JK41ZILfhpv9ojYzf8LJSN8k39gbMqldIwZPxx78JQAIqTDxdAo0bpDDvqvGt4Q\\\\\\\\\\\\\\\/Dc9noSwAQ2QiWvWskcEiC7hRWPNgk9aJLed\\\\\\\\\\\\\\\/36ESg4EwVmGpfBcJBWEaBqNlcURJQdfblVCC5jFGmlj\\\\\\\\\\\\\\\/u6NjCDLaJx3jJZ+vm8WxEfP9JFA0twL4sLOqdPZiUVBh2NlBMOV94C4zJ5kG8b7SQLRrHTGTpstk+be+hj9JLKY22OoOVSoMYKM2HgAl8fkg0Nv5xmW0QP\\\\\\\\\\\\\\\/ferjye2Kx2X+Mc5kdBsfXfSliAvihJSOB2UiAggqi\\\\\\\\\\\\\\\/156Vn9WL5xel2AhgF+J\\\\\\\\\\\\\\\/HVvF83lXS07AupiaZlfJMk4jzhz5Hgsfl36ABlEnKaDCi\\\\\\\\\\\\\\\/vcZmkaBE29WD0oLHwgKLfPr2Zl\\\\\\\\\\\\\\\/SsVyU8MMAKsFOhoU4KKiO4Jtbedi6DeVkXaUdBdHeq0aQ7VuAcbXNxFFbSv7Xpx8l55+6HiiaI+FIFmK4JH\\\\\\\\\\\\\\\/eDOSMFS4tTBPC\\\\\\\\\\\\\\\/aGYJr276BQ2zbCmIJQe338L8PfdTbH5tsS5eIfFSC7lORPbLe3Yiq1FkbTZr6U2XqmqE1eQk2d8F5iAcbbpFIwUyqaNW+qD8AFFTFnvZE+QZzabgyhPiSRCTNl1gQ1uY3lslWhl5FF8xPD2PW2HAWwyR1GsPdXR4W61voz7JtFs+vX7oBWb5tyJK4NEQW5zSq00LREkwCuM3iXkq5juieiLtMxjUvjc2MahNJ4Ir55\\\\\\\\\\\\\\\/egvxwhL\\\\\\\\\\\\\\\/AY\\\\\\\\\\\\\\\/+uR\\\\\\\\\\\\\\\/7EITf+GZ\\\\\\\\\\\\\\\/BiT1xHl\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/ZHdliabUY6M4z4v4iM5pkkZimF2EdsP7NoKr9zIuBkxiCAjsNUcpj0jTCNN3iA9TjS09v\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/8zSUedB3B0av\\\\\\\\\\\\\\\/gAKvdhHvjy2pj6onkiGC8lBfcdtXm6CfPFWqIwHY\\\\\\\\\\\\\\\/tL5sfpxVry2ZoVmg8yT\\\\\\\\\\\\\\\/eX8EwdbEBrUdCN2K2brTu3Q16Y1NpsyjlTB09qabn5GB4geEo6BqIQ7z0mVsQ4qPb+IMtNCcfxFVhOzMjM+gE+i80WY+G0TIjCo3Z0CQK4WZyYpPBFBAK4OR2\\\\\\\\\\\\\\\/u2HNzrUVf9f65ZKYLoRczVgWYg1p53eKfL6wRLtZNMu1qrCCwPQ4uWLE2O0zPn5iFrsTHprgVOlMo8h1szgRGFbhitXYaHRjZjKgVOif4\\\\\\\\\\\\\\\/FYACf1g\\\\\\\\\\\\\\\/O4XYluofSz\\\\\\\\\\\\\\\/PedsY9W5fpJvYr6bYM85cj+kCMEpYwqetDCdO2Z3XLNf0KT5IpYZG1boqgmsLgZsvF84rhtLakTGpXRvOBRoqXyr1YOsB+CjmgEvdXzA0FaqbbN38GMgPykbXA\\\\\\\\\\\\\\\/ZlLWeAINKrlvKDRFnc0g85NZjCS5OMGjO0PbYGWANBiSoqY\\\\\\\\\\\\\\\/BBaZSDRexG\\\\\\\\\\\\\\\/gMdJAHJOoFsjRkU0GeAg2MOmS\\\\\\\\\\\\\\\/MqXBOEabYSlEjauDb95wO+biEfxuhu+JCZTD0lIflxZrHx0GA5C4kJdEtPNKbCspTk5WusFg+Q4t59\\\\\\\\\\\\\\\/vEYvb3Uy1Kj1dhSUkXDORvZLBXm0BnXf272wPYwIanjqBKDsr5lzQrzZCMR2AMZkAoE50=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022VtyjUlfjqc4MacD7UTiB7g==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022c7dff6dc5137d54603e68c3c129a93d0b358951c1b1442d001be8c8c15039b8b\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1343.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1343.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1217\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1217\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1217\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}