{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022lxx97lj+KM\\\\\\\\\\\\\\\/1bSETre41zuqnGxkFkrbFuE4CwjEW0UjTiC0b\\\\\\\\\\\\\\\/6nq3XRrhQtNdBT23eeRKs233dujUL+JpNuCtT8bRYWBrV2KDyw4ZJjiOCBuWRKafCH0fLRlk1DQHVrMlUYtSRhETpb+qeSBuPfCGSAImRrYWbDML\\\\\\\\\\\\\\\/hVeOt0v7HUk5UpIxoMLbQ2TbG5SgseRozb4gWvlFXudI5C\\\\\\\\\\\\\\\/fSP4bJjUE\\\\\\\\\\\\\\\/G8G57TKIoZgXhHkdON0ORN1I9eCrCw3YaHSXL9cXmiQAlEXJGvl5R5a+kwva7oM9vMkeMdqWtwxU1BLTkrk0XJUYg8ho\\\\\\\\\\\\\\\/VHlb69RD08yO6Brgj802Z\\\\\\\\\\\\\\\/ZRdMmA9zK86eMSHYblE7JOXiuBeNfZVE6\\\\\\\\\\\\\\\/Z+eyfLAejGZuwrzna8KJhBYftrqw3uxq1ZNuPNOYGRQbNm6jQJKYvTseU0Mkg4VWtTdDHsRJwKfPValI9Bztf6vMW\\\\\\\\\\\\\\\/4t2Q3+cbaSy7RdUAYafxkhZd\\\\\\\\\\\\\\\/OCm8UOO7+m3Vv7IzgOnX6PmTxtWI+18WppgE+20ccsbDfqgHB4TRlDJSzYgboy5tsRR2sOwmaUyeHg7Ai+Acc\\\\\\\\\\\\\\\/xEV2x10cgiBzXFsc7BgZhJRvpBGAdPt8xF5zgh\\\\\\\\\\\\\\\/3rEhx8FChUToCf1NC+vT+k8jp39wEXuAeC3m1XJs1OIaAgJTNbZiu01vxHKK8vI59e\\\\\\\\\\\\\\\/UD9kWkLdhrOsP+7wZ4Bv7GOcB3nvl2r7khjBBr711p14709toFGmHUFyHofvwoH\\\\\\\\\\\\\\\/0VeQQOXgCekiO2kvaIwq0u\\\\\\\\\\\\\\\/Nb+Mi6RsUKrw+aNNhlGPq7T\\\\\\\\\\\\\\\/ixkZBAOsQeRt7\\\\\\\\\\\\\\\/pJzPYybF4h15tK8SSUlhc9HMmw81MxtGjAw8OVyKj7ypUqMn25RHEFwWuxicmN1j3Xfj+OFNGbEsDqL1kPkogT4VV8B5VYyHTalUlCBDEAm0J2iZL0KqBRikUpVMq7ejDz1rqFrsyaiiPbV42l+hBtTNvUx5KsUcl2lT1RvPAyi7qIcikfOr5WIT3y9\\\\\\\\\\\\\\\/sPnpZw1j7bsmxI4D9Ok2BbB\\\\\\\\\\\\\\\/r1tCkKILNLbAyMT+yYAjxA\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/ucGuJJS95ab2loCjwVIhZKzYrv3dITYgi+rZahXqHq5zSHq\\\\\\\\\\\\\\\/DZLODv+tFcOXrCYRLI+nrgaynqqdG7P5wr6Cp1e4jSS3t+SVL5Es\\\\\\\\\\\\\\\/alfeweq9WWl\\\\\\\\\\\\\\\/7TUc0zW\\\\\\\\\\\\\\\/AyY7Gqd6Hb83YviNuP0mNbZAIbfj8Qv5sHPbHY5UzKpbny49M0M2VHod2ATIWOV1R+NJV7ogzuw7nETMXajMwsdemxm\\\\\\\\\\\\\\\/3lhzfLuZpKtaSavtDLcfF7608ZKGn80954hxGRvWAfR8MwOUyvmepbfy9cWnlU7Kqui\\\\\\\\\\\\\\\/ucMN2\\\\\\\\\\\\\\\/HAysZsmPZ9X51FAlSia1h3aa5OU2DnC1a\\\\\\\\\\\\\\\/maSUXb2VlLXLExLiWtSSpY4kairwaPBIyd5PdRtaKDFL3+FpKDJeLuHFrUm4Rx8BluiqH77ZbN+CPWEckFJlXtt24Lk9UfUYhLgWkME2jHh6K+O\\\\\\\\\\\\\\\/9eaD6mjuTp5yGVVn2YhlJ6mceAdVutmmWZJUFOysTJwbVxR6fvS5t9b1T1s0JQNRdT31I6QKuFBKCxCRijW2k9Ul8IwckfTLWaaFDooGchk0OPwjb6lV3s6c2K1cxMIQUk\\\\\\\\\\\\\\\/uorYrXv+5pizQuqfZU2rj6xB+Dgis+lyDe5ObTKM1NgxNSxLdKLQ8UlfbwCYAgBwR77\\\\\\\\\\\\\\\/jY5nZyUSyvF+4l3BiottzZD\\\\\\\\\\\\\\\/11hh\\\\\\\\\\\\\\\/Wd0LoVcHr+NdVU7zCv2JZgfMbhlaligReMMdTvMN1QCFNk6dHlXeRo1yWjK7Sh3uU9rMAaDFvXRhSWyrc6qXQH\\\\\\\\\\\\\\\/HxbutPTq9WRTet3Ktys962k1KRPuoepIBgVjtcWqZvOifsZt8R5wLYCssEIyKgGD\\\\\\\\\\\\\\\/e+\\\\\\\\\\\\\\\/AR8NHKPcaGJlCewtfYFymLgwTJ1uf9AfG\\\\\\\\\\\\\\\/U+BmfK9ga1Y\\\\\\\\\\\\\\\/W6aV7oiUoQPjelR0TwFHuvKM72rzxlTtqNIMMzsL+0nPrUqR+yGln9VjYMxQM7o3hs7Czih7mz+ysSOpMv1txfop+nVJVkaq+5K5cclaUsBPieVwfU5gXTcci8yCrNUsDCxOqi0gvf5Eo9gzOYm9pG9nprkBtWM7DQfpisG05NCczQbgOjwyWVzBNggH6PMlbPGbx2cGRpqB\\\\\\\\\\\\\\\/ifX5U0LyqxDzU0LIJCHZlhYDr2Qr\\\\\\\\\\\\\\\/CdUU9RwVmeItHKOvWkmcCIiH4m9xBYjMQzFrJPEHo\\\\\\\\\\\\\\\/tage7lrus5FsngkURikwPHIvYDttgrVzf1DgaFxANDarsE8KBk3f+7jU\\\\\\\\\\\\\\\/aYwdH7AwWIj+L4\\\\\\\\\\\\\\\/3XuGEgUoc3puOps4koW21EhHxP3Ou\\\\\\\\\\\\\\\/keSYzPjaFjOjnEiNOiopcd5nMVnQif4oR87zCBELip3keXA14kIekzkg38SPj0\\\\\\\\\\\\\\\/N\\\\\\\\\\\\\\\/+CO0W2kPniS1rIBwXwLpXihpxV\\\\\\\\\\\\\\\/Zots16aKrY7TKmKc6Q\\\\\\\\\\\\\\\/RRKsa545CN\\\\\\\\\\\\\\\/V+H4xSfcFeZr19aCgi8CK1xBpQ9350xAsgxdYrB3Ytkmgd22igrSm1haWw+Wva7FOOgqjtZXB\\\\\\\\\\\\\\\/cmQV54\\\\\\\\\\\\\\\/f29BK2Rfq4C5JZpttSt8eMjtG9iYSbzoyF\\\\\\\\\\\\\\\/qNMcsc71cA\\\\\\\\\\\\\\\/+GhE4lmbLyydIURYdS76KYj5vgVHN3ktr+yog5J2tKFQt4+eROsfzebi+GdyLOw3bGznGxtJHG3rgI=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u00220iTxbZFPc\\\\\\\\\\\\\\\/Q2SVASH8bw4A==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00228884a969bccdd14fc2dd152b83b59932d3e3006b5021b042b0c8455d5dc9ab0e\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1518.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1518.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1362\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1362\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1362\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}