{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022Qe\\\\\\\\\\\\\\\/4jPObsZhv2\\\\\\\\\\\\\\\/SS4xZt85PlMV4hTgOhooybtYsWCDxHZeCqyWOeKB4SqqBMAQBWx7k92L1TwRJn0gS4plhhUBwQMph7IkLa\\\\\\\\\\\\\\\/9hYelJJmVNrYXxE\\\\\\\\\\\\\\\/c8f2ypfVRftlxGeawgxS4pnnE8\\\\\\\\\\\\\\\/JZf7OcI341M23YSz2i1whNu7h8azCMBHPFAlLu9\\\\\\\\\\\\\\\/h1A6ImdLbMt9In8zR6og+q9esk4tFYsQ\\\\\\\\\\\\\\\/y05b5XZL5tamOjzsW0XDMyZR5Yo2+6TxYdBgBBeLJNXz3uDnG1tbvRJD6k4zyZ4EkdsFNuyHf0UUepG6\\\\\\\\\\\\\\\/BTDTPFXSY3DqIqYuMpZ8qq22dtHMDuU9UUiO7pDbMP6RejPnxw\\\\\\\\\\\\\\\/HQgbpY3TI4VLCo4hmsiCy6zT+gdy+rUF6Qw+f7mM1FMQJzFuSl2ZKLmYF8AmUUi5nL+8s8B93u98nBweYcAw3eWlfNCUVcCzem9xTAiLQ2QEzHTTIBUzExm++keVr5tG8ZZKNCdH0OEfKVueScbObv0afdBNhA\\\\\\\\\\\\\\\/J3MxtuyXGAM85uS6QQnGO+CiCRhtGDctdj\\\\\\\\\\\\\\\/AngOCdlpxhZuX02u\\\\\\\\\\\\\\\/II2R9NOXR9DKOZEwSbC95SoovCsg25Vi7yzrdAZ88+UGXiky\\\\\\\\\\\\\\\/kQznpLEwMiK8vXMzTuCWbBliAD1lw4FSgHv1mlNsLbXWTJf93akChzPhixm1n97Q4dpu9cqhYQOc4g8lES8AWaMj3EXnB+vi7jSUvqM+2jFB6+TsfOU36C9emAyi2PHsELON42Sv0qp2HlAcaK25yE3HJ9PH8UJGI1tOeDei\\\\\\\\\\\\\\\/IGwI44VvhTzCTpVQ0pGkCl8Oh92Yks\\\\\\\\\\\\\\\/vwb6pr9n7lJ+wuci\\\\\\\\\\\\\\\/SocpsfMaEe0uF5iSslciN9\\\\\\\\\\\\\\\/yCR1fFoU21Jjql3LjCp71EGI2YwQzVtfMkrWKK8jDKpbEOZ\\\\\\\\\\\\\\\/tAtagoya7Hn8lQqOVCeabxp5qzVrMr91MoP\\\\\\\\\\\\\\\/y5NBlaZdzF3v5X\\\\\\\\\\\\\\\/0dD\\\\\\\\\\\\\\\/co33vPtoO3LIkUHVBfWMtahzjrj5dtErcoXcT8VCnZfBXI86xLLfUkfo\\\\\\\\\\\\\\\/cKdWQzB+febsLMgIWQ2qphXb\\\\\\\\\\\\\\\/0tA3MdcnHH+dOTPyUBMxv+O+ZcC0Fy15t7RM26mpgNV06CT1L1CbImpFqjkyOYs3TNO5rBU1NPDRWT7uSBgv3C+U75CE3BeyR5xHp1DWouKC6jLJ12CvWyjxIXFzlFtMVMst\\\\\\\\\\\\\\\/0seKldI+fvAgvmy0Hg4nkxfVsP9JPz\\\\\\\\\\\\\\\/g235pT7MJVYfBknkVBcpSUDc+9wBG2axxDw7ZAo8jzmvH6nIABlIxYnpZP1aiJfNeeoPcC7DPMOiMF\\\\\\\\\\\\\\\/nRzgHIlepgUZyCXpZL6dPU811AgXjNdojhD2KDhtbEDwJAtMXOIcrymlVVihqSlPZcmuTkofz1dlwQi1da33raJk1VGL3nEJ2Y\\\\\\\\\\\\\\\/w7m19b7z3xhexJl\\\\\\\\\\\\\\\/B84jX1flSoLxi+bWbvwrWY1sRoCa6cwE0WWHfanBIAG7QCjVWIP4XIWmoYIO05jidEMMTbsS0T57kYFQ+xJ4+5OqwhAT1AnUb252+h\\\\\\\\\\\\\\\/0XcK5w8VwngjWJZXRQ9Til4LqzSwfrJZwWSYjlSFLan4xELDPiLfQJKMCafmLGw6kxRe5Tz45B\\\\\\\\\\\\\\\/7Iz\\\\\\\\\\\\\\\/IFcjBVF1eMI70RIc8YgVsXtAvc7dKikGiiNfx8v7yD97i3AzpaIuHogaqtQ8XBM7mJXwjtGRup+a8MQ7l8yJzrZHhW85ctRod5aweLRcPBLg4nuuPWxFv679fzcOoqfmO2ptkipY+8uxH+ndskKCaZC1pBCF+5NH1ryeZUo0alW7t9hmvk7OqN7Y9C4x7TPpCrHiW6mevZPWwHCoanfvWSe+9jdyygiivyF2ic3idOYCdlOSfoK7oYxwGvQDuf8c1OrITHHJEAhHdmGPH7MVX\\\\\\\\\\\\\\\/PU8Mn0+mgCLJtxeCbvh2af5KbvohA9KyAQj87Qlpw5rgOg3x1+XVSi37b89qfpIy8AyCSQf0OGeLZ5sWLdfunutIf05cfrzBnwUiQZVpIUvbak5NsYBask\\\\\\\\\\\\\\\/V0wfyxEHEUJYp9muiXD4GtUuV4QYpnKz6pLa8veR\\\\\\\\\\\\\\\/XLee9TYteC59\\\\\\\\\\\\\\\/CwE78Ab2cATR4jmSvaq6my+4DEGlyT34b\\\\\\\\\\\\\\\/RRLzRLLlARDAzlRZWCAXbdQF7+lUuClYJkgDC\\\\\\\\\\\\\\\/C24keT2IyvUAs3c6SlGPhN12dCyzSeCLeQCJDXNSahAI9LAqfaPYLK8Or08EtmXwJJ6zejSykQg2Q8IO4sMR0GcXs3\\\\\\\\\\\\\\\/Z+vi2zWMYeWp+qRA+CydR00cljjPBkudQjX7cg98mijmJd+2VLGKPZwRitoHrhnW761WSCx2NE+SW3zYlRN0G7bvaIYd6IFGhgtgAv0OKiHEedETGxlJB2MUjlPVD3590ae1HqL4X0PZSSWHS+ornKFU7hiXRoexX6YU+U1UzYrW3KMPFegnFy\\\\\\\\\\\\\\\/7jUlScKqbJuOtgqDZrI+jpcsk2iYeVSZ5OEC8gD95jNmZ6vup9GtE+ZCo+2OE7hXCIPC567cPNszHig1CdCi\\\\\\\\\\\\\\\/ke+IbJdPkbcKsPnvgqz3CG8I1R1jUUJ9qz516DttZkwv04SuRJ7Fm7Jbw2joqW9Rbx3jdXEJm0c1K4nf7e18d8KEutivdRYhRaUdBhEY4lUm8s8\\\\\\\\\\\\\\\/pqzDzP7F1auw6Y8XCPtd8LzNHEiuR5alpfXWItU=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022MK53DsMT7BPDNR1mrFoKmA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00225e5b5a49ad4fa2ab2cf48c15c536ee9667b6822b262f8292fdadc7996952fac2\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1576.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1576.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1418\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1418\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1418\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}