{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022ksQAkrj0BHk\\\\\\\\\\\\\\\/FpGEZUCyl2Ab9Dvru2a9IZqZgyO0WSjZib9KpjZUcCvUHdE8BkMT8b4JAbLjNKL\\\\\\\\\\\\\\\/b3tn0SzSj6qkYv9yiyIAFTAQXpQ+ClWQMm2CxxT+7H4a0a+3YEtmmGT9i\\\\\\\\\\\\\\\/tApxNiGlnzkfrhKmX8kgqENrgd3omWQ6wqYu\\\\\\\\\\\\\\\/tujrI1kSn0qdBwBwyqVoGYFGB\\\\\\\\\\\\\\\/pVDQMrys6S8YjVAeXR8aTmABpyyjh2a+BrCekPATBg1zcBuWruVIVkC9PQyM+CFv5nSEOuTziSYkbVb9cwxc5svkJ8M6afLubLQh4VZqgkVhz4l0wgqo2Py0\\\\\\\\\\\\\\\/V9vs0sJl\\\\\\\\\\\\\\\/QF36s0z\\\\\\\\\\\\\\\/ItVTFjEL6nmSXAE0jHyx0mXTy9Y2lIyky32gj7kyi2nWjKh5UbrTvcVifxhIfTqvHQtgVoBRKAAmGBog6+qomVm\\\\\\\\\\\\\\\/qNX5VAT8GbwM2lHO6TLk53YvYk16FHchQciCPAkualondaEvM2Rs9+gHIViSlFWU6YuB20QsK2aZXe\\\\\\\\\\\\\\\/eRMQe1aYCFrRxmSIpefV8Qsd70KGd8X5e8fFV2yTZh6WtT7A4fx2yIbTHXy7VdImTEADT8Vwt+ir7VemGYsWdTbpGvPbO+c9wSIy3vRzt0N1DT3MGezCQtNGsHwgMK21D9bOUiFRmzmZuzQCXwrNGXEnC1MMTvj7vLqJ94SHxjXu8BJrXKcczBUYYkfHN0MCcQelMIaeii8JVFbRX3h\\\\\\\\\\\\\\\/bAfLO2LWXZs8MdwsaoA8rlBUVeag\\\\\\\\\\\\\\\/HuAO2P5\\\\\\\\\\\\\\\/8ByeWvTYwKuAktyAJzEkVrUrlISaK+j8FvjxQATpBCaslRuA7B2zPiQ9wYZXDYaXMt0JgOFuYLCwumH72wha+s2KDk\\\\\\\\\\\\\\\/GYIC+GsEPzpvhlF5P+jF+0ZFabbN7+Tfiq+p3eyLqecjzDz+KygOB8kxzFtiWbuPwS7BpGUWXQArbdkNt8y8eRGQeIa8kOviHq6RdaP49gbeoQFTYDWoQyeiYG30gUdG4Xx9zCOo07J2eJ7uORiJX3Jnd\\\\\\\\\\\\\\\/HBi6gWgMguuzaf8gggFKAM0PHD6TqpCSBj4Jn8n8CmwHgVKIJVfvZciAlU62d5FE\\\\\\\\\\\\\\\/x7IP1ZoUrpSUOu6tzUgKP8adJVOplaEkmyNAtSvYe1cku\\\\\\\\\\\\\\\/KbzEkf+OBLBCDM0kCqEEmRrUdUL6B\\\\\\\\\\\\\\\/VAhfk5OI0c5GyFQiojmgwVgSYiTVZPUFAA7Zb1ZtMiy\\\\\\\\\\\\\\\/k9zqFAjsoHGq+GPVUWZG+HfPXngn7N6LepMstC1VeFlMf0qtnPMMEN174k3iehYvLEjGxfKdqnwunjBswhxUwLPrpmrt57ngKfR9aepBwKaJ+BXTaTGQIhyMOiFS\\\\\\\\\\\\\\\/cTzL8ZnfZh6\\\\\\\\\\\\\\\/7vDJty2uGrpLMOu4b5fktU6mMZzqVZl9xNZG5RIlUHv6SKk+id8qs3pTtHC8WmkyMAVGmbWtxnt7XrLD+gM5Zgurbns6Gaf9gbQWMCCW48KVgjT5ipFcjCAJ\\\\\\\\\\\\\\\/2KH7TzfpzaHF5+4cMZWJXecqdqVNx6oF1BKtE27bM1PdNW09Brst6cJGvjcZMcZVvoqa29Adr34jeQmAjoRyH32o6zI7\\\\\\\\\\\\\\\/uRDXmGk8NH5Z+tlzBHO1yeoRm1Y8o6jLQ2xLNZ4ea7VsavbrDtrE9mck7lfeRepI8ilGENbwuc8r77x+iHE5CnSdAbhhd4AzygkRZo47e0RW\\\\\\\\\\\\\\\/a7R9mWbs6FpMydp9lCwUxfWILKVXtJPdi05JRXe2dK2LNIor78TZAvtlDUmWOgqkqJfKA1\\\\\\\\\\\\\\\/SniHj+FHSiWscMeB8kvfNu2yvqQiIuCmRcBw6V0PCajL1L0sViCzG4681ijkIxtq+X0QHSwlLkYAhCMMfwLTyS3JBhBuCkc9ccQ6RMdTfo5rE4S5YQdOBGuy0dpv3HZf5p0vd3cgvNDvAlfrIBIRICQcBA0RqUy921f9aPb9AqX34GmHwgNaHvTZEydhG9wjOXgcYASnd8r0Z7Xdcs6isqJ+YDFy6\\\\\\\\\\\\\\\/7PZWPvKRVnPw0Nnc2HrKc+VgxUoNEU91kbYh3Oi6a5y+00ekLdCs8AvYMcc5M8MubNYs7FCVR9\\\\\\\\\\\\\\\/++ApPTBSt2\\\\\\\\\\\\\\\/40z9xJ0PgSnpkgg1dybkWqc5f3HWhOUDc+oa0nsd+8lfwXV7IUIv5\\\\\\\\\\\\\\\/EIoBDq2T6nUFZPrcSDaHzg1eyxLfO4U3xvOmZdGjgVI6M2usIVOSOt3UAPYMHHzdaDoN3oMzSMmbtwUuM4UkAxPY5ZXG+iKV1I2ZY\\\\\\\\\\\\\\\/8YJmX2SF3IcWclVF7j1UpjdJJ0au7mXFpaHRpR2SghhrcFU0cWKIAIfIXy8vWR07bnBmCgKybK0w0qwnvJd1fQiWwh8QFX1rp3havto8RIgtpluY6sRvHNVDltgzHpYTT0oIO7KdO7yOhW\\\\\\\\\\\\\\\/qrQ2SQLnzVj+YWtS\\\\\\\\\\\\\\\/yNBs5igxeGsZq0\\\\\\\\\\\\\\\/cl8We78s4c\\\\\\\\\\\\\\\/u9\\\\\\\\\\\\\\\/1u1xzE8q\\\\\\\\\\\\\\\/uMiS6EF5YJjrbSOGU0Xs08K2feS6jR3IO83Icp8Z5SAFPnDjctSjZ7CEveQQ8C3\\\\\\\\\\\\\\\/cNQtpZs04zyxfI9izoV+HQIavVzQuSdD8uwCdvXbbAFH3oNkFUkoKP4oYnx3FJkbW5ME79MQ1qAJpY\\\\\\\\\\\\\\\/nus0qXubNcCywlMR7YnDDW2bwBKR49szT0Oj3JymsHRCgk4\\\\\\\\\\\\\\\/QJ9Fi94VtIksGsA4c8hADrl7lciDEepirDfo4w=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022UzNWxiBGC2LhPMTsjYNyBg==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022456821b0cf92d16ef567abfbc0c7808da3feea418442a350bc6b5cb80f52ee85\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1663.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1663.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1499\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1499\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1499\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}