{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022uyDiWTkK+Wj3IOeYGQRNp6QuF3qHk22AqiPJy8b1InbMaL86BPuvFpsF7Y5qzaIgBUuoX5FyONEIgWtktothOjRrYjESKsKWIQz4tDtwp9FwuIozqRNAJ2FwhbA4xphfCaZ4UrdBp+szKFYGPisZ5Q+St16oHfgaZwx2MtpnFYTpRkk9eDuge\\\\\\\\\\\\\\\/USPy+6Yqz4QqtpP907Usc1tIXPzkMuasduvFOI6W04OX5UJO4g9n5GO4+B+EtX0fQxYRVOqLKfKpjwPthkosqFOP60XYNPP5I8hVk7pgdaR5lcQi21gZF\\\\\\\\\\\\\\\/Vg8IrYjoEVfiYb23IU07u6z4EZh6iXxp\\\\\\\\\\\\\\\/ZgXLQLcXJ\\\\\\\\\\\\\\\/vWzylaCGdHQwHNPJ1Vji1jiMcSEXlwMeBQO3LJYm\\\\\\\\\\\\\\\/pTWVPoap6kgs25PC8\\\\\\\\\\\\\\\/lS0gs\\\\\\\\\\\\\\\/85vOZ6Qe8n5NvgN0G2W1rtl5jbsZSuUp9u3JUMFZRyE0olJPPmjOMDJNXCMGIigIg9QxgY3AgXWBx90ETRaOJsWGP5Jw8dq9y0psbrrrG4HIoowId18rOLcaoWf\\\\\\\\\\\\\\\/5wazp3CxkJ5Z5k67M6A49trXm88Nk6ZuJbVUtE2ZeNOe5h9JDPu1aaIUkvrTDhN4W1ffgorIN8nX5jwKMB46b2x7slyh7q0GFrVvn6u+9w4endaL5jUDyGd4bzQggYpCER8ok45G\\\\\\\\\\\\\\\/pdBK2n2\\\\\\\\\\\\\\\/tcAtuWGcyNmNJps0NfTUzenAXm\\\\\\\\\\\\\\\/eMET+ex4yBLOe1iTkojZyN6hsXC2MCPghvsesJzyLsQPQU4Rf8vC5rp\\\\\\\\\\\\\\\/Vqbp8STB+Uk3mnvieidx\\\\\\\\\\\\\\\/AKrCS5\\\\\\\\\\\\\\\/gWWMrHn+gqGkpEp4WP+u+xVYQGZgRTuPSie2z7U0VuJbbyxPl9blxRNs8rwCSLyYiuFemWrRHKmZA6I61B6XYTmEskTOtNUNIkVpWxd4HHIfXvL\\\\\\\\\\\\\\\/dED6gV6CBgaoYTUO+GkGumc16nOa7kKYyyBYH4+FAvJDPk1C\\\\\\\\\\\\\\\/dl8BUiYYGGKi0L6A9HBWzR8Dzh1j8Ph7yfLS2SRwnnZUjG3\\\\\\\\\\\\\\\/RPJKEYpbAOgVkYmZOqqN4MfmP9xuxFA4ZB3wJspw8+0AMtYPIldjNmQhzOXATwh9Umbhcz+HzgPNXSxgV4DfY2mfu2KJ4SuD36sKBAuoz9vLa5+SRqQMN1IEVf5rJXsYLi\\\\\\\\\\\\\\\/d9F68bh13pOSD9buQVZolD97auVF2qc1eYfeuy1W+nL6Yb46BhacWSxqd6hJpPQTurj5j\\\\\\\\\\\\\\\/+GRnh6+Ehsf2kJ8tZAz3gtGscWqBNP\\\\\\\\\\\\\\\/ASWIeUc9j1ooeLdyYKkgsWuKIVgudBqlf2ZK431W+VCCbOX+QfK3BOSXFeajJHOkUe+GmWWc0flZXlYUJ2APcpu9XnOf9f2v+yrZDIiJluPQOB3\\\\\\\\\\\\\\\/Ald208RMU9m68uRTxOhMzE\\\\\\\\\\\\\\\/0kQOIIDhpKgwLFquGxl7ZFef1\\\\\\\\\\\\\\\/QeTWdJnC+pYb9\\\\\\\\\\\\\\\/1Yqj+hKbo0YYCWw7Q0n3vh7MgzdwE0C0\\\\\\\\\\\\\\\/PcR+xfArwHM0wp+go+kBOnRdEjXJwHWlu794BPv1mesWRSQmFQEkKoFzncggnY0Xw+5QSVSut5NAkA36fpzvY9W+cph4Mymgza8LupmuyEaNWhfr\\\\\\\\\\\\\\\/lRWPINzx3TcJlqqBI0o\\\\\\\\\\\\\\\/nzjhXFuovr2A7+ZhTyY9HYpekUmT+3C3hEQn7VWYKM3PdNrVRSmZW1N10CbQSpu3phz\\\\\\\\\\\\\\\/pDb3uukVESY8Y7n8HPGjvA6Goxk2IpgFnEV8R5jKIfPk5+zbA7sPXwHPaOVBD1+Zpnl8osl707FhYVZv4YglO2bds2m6VYKsLk0xo8fboVR80h+TulgIQ6PHnRA7u+egYEyt8FnujIri\\\\\\\\\\\\\\\/JIkWYROarIMs1\\\\\\\\\\\\\\\/TTJv07QTYzB+u9lWb3UUJKYgE+2\\\\\\\\\\\\\\\/wkPwpObzfyzH8O90YXXDoxBz7KWQJ\\\\\\\\\\\\\\\/bawU14NuRwlZDkC9jwD0kF7gwfO4OAb56BIwNGpmcuTqWkEru\\\\\\\\\\\\\\\/DLbOCurZq2GICYQRgJj4umMtny+eoX+xUqxLzk0Hv8PwxXoCudlwhbZHM1CvL2zLYw1XmgZCqbcNUAqefkABzgAKM+eLl2cCiz9jqYl4RgfX8sIpugzQhkDj7mhfKx\\\\\\\\\\\\\\\/oSFT4KpkQZUEU\\\\\\\\\\\\\\\/Ef8QrR2nvjgBWb0BGAX1XfD2GK47XmWAvwdBVDBfCn4WNOI81oyZb3Hw\\\\\\\\\\\\\\\/hcemgIxaLLu8\\\\\\\\\\\\\\\/sj82iky4nPfFPWNPIxJSciMX\\\\\\\\\\\\\\\/o3exPuqnmSoFWG4blltbovWNs7GGukazwkrNgx1v5gjf1rn+a+juhE8Kx5uX4nxepAJ1MWzQCOTt3i3nrfI2ipcugKcvxJGLypPjKpSQWKAjUD+FVa0KOCj8qci\\\\\\\\\\\\\\\/cXLkT3yx\\\\\\\\\\\\\\\/stpJ5\\\\\\\\\\\\\\\/+pbX3fejkDEeWYGsSJLiMhumAQQT4XVY\\\\\\\\\\\\\\\/Zznuatycj6qYDUrtlK9GlZPOkvVjsXbPchKxfrywkHlz5z28zP48vzAAoJZEp\\\\\\\\\\\\\\\/cw2iWcQIPCOlEDRi9mgLRT0eHkOgpMs7c6v9ILsnDnOWgs86LZRPdEmYpP9+hqTefVp3pPjVOm1betsCfyTCMiUWKVWFK\\\\\\\\\\\\\\\/tBkMPfsfxxQgSW5lcjXVB5tSI2n+FRnZpdeZWO2\\\\\\\\\\\\\\\/+cxQQl6FNbE5ZD9wRwV07A6J+N3NknuVFCsLSy5d8JKxKc9AYEKF+5sHrfPEKRnuPTsZ8YzL3VVaG50whv2\\\\\\\\\\\\\\\/+j0l98hErZ\\\\\\\\\\\\\\\/Trc=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022AR1eypgEkNXMBPi40H+7IQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022d0a352eb1741051c032a5cdcbe4ad8d06ae555bac1f4920c143f249a4d758945\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1568.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1568.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1410\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1410\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1410\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}