{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022ZkM+Po2fJftfTH1zuBCWiQvpfQQQ76JjD84K11RZcxxNLImDCysGhbZgQhf39nw9K0gcMzH2ICGefrVoJzwOw9F9MxXO449KBR+9goUSIAyP7fEg2YNmaps+FtUuFyyP8LphqRIQiFi3pKOVGv8vp80JG50Re4HMWYodsWGsivlhZB0U5JcbHCiK9uL3J9RUF88bBQ5rqVUAKjsQYbEd1oLEjoeMxH9kTMEWD1om92cVn8vf56Fxdvgg2s1BAwT0b02e5jC\\\\\\\\\\\\\\\/ZiSmMVpJhgfqkRWMzf8OR3z4t2UIbCHMiVav+zYECL8AmLmeSGRnklW9625b92a0YzUp6\\\\\\\\\\\\\\\/CSbD\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/N7KqdnH5Kv+Xz8\\\\\\\\\\\\\\\/cwegQHY8oPCJ8s+I7A8saHsj\\\\\\\\\\\\\\\/F\\\\\\\\\\\\\\\/Nwpf1SzIahHeGQic6NUS9vwmjr6mMzg8G7x7hLOeWFMrUqiUvIZgy86np94t\\\\\\\\\\\\\\\/5P58hA85tYqSF6eUiRB3uKv0FaaD3Prc8ZRGTExNKDDMGu\\\\\\\\\\\\\\\/4YGBalM3E7k1y9qnuzXeMxjjsRUeXeJz1zXHI1WeFt+rwEgNDt8bEzt3wPARWoPO1NWQuztjqXS\\\\\\\\\\\\\\\/AYA12IQ1++Vmhfsyq+BUf7ZZrXceG1lxKwznAk1QygLj4sUH0dwzP+G7DW6ynfoQ6nX5icMeKnzy6bkPq+eXE4bt8dtGTaqTyGAQ3EcZhTWrMkgJOJrnzXaME3KGfi8Sa7Ji+c\\\\\\\\\\\\\\\/sR8vD6Y79sVn94G2JLWWZSbAmxwCDVqKR5vrFc8fQ3IkYZzTQwuFpH7NK0hOReH3u5FGTar6e9slYddAIFOfOhlCUoROi3UuDbOB1Rp3bNHDH5vnki1f9f+Z+K4sXazhdGlBWaVGtoTtQggZi+EHvILLOJFHifXBZKzYqmyYRQxowX\\\\\\\\\\\\\\\/zxgC+aa6QIFbbGTQf2wzvfI54p0hKilz+LFMvKpeLUADsi1QaUisc3Mmnq5zp6PC3+mGpdwtn8wJhIDiTb8F45lzKyuSxJIxiFVsq01XzedMKC1y7GCR0reoIkkeuD+XZ7OxXR5JmCdnU1bZ0mQ+xULYnw4pQO\\\\\\\\\\\\\\\/EpA0sA7fjIC8OVqBaE68VvKVYVUg2WB3oCDiGp16\\\\\\\\\\\\\\\/EdzBpf8XTucih494fZTBKPLTMlL9uFEljlXq80tnkwZUqkgU2Rff561qpRBP03DewH3bmOF2+eDUgZrVvBdebuGg4uDtk4PimQFEGlcRB9Dcq+dlNzrYpOnZi7xCPZBN8Vk+tcXRgyvxsmJgdUeg2dYdpFqk4dS7Bto5N5+cevEPQ5gXMZWvV8DZSqibqdNATRGi9pLfa7fv\\\\\\\\\\\\\\\/DvMIOHRrMfhY5iaLVKdCujzxTqLgDQb1SUqDlsWyZTMPehWXfncEkY2Q5tyOl5XtT4pAAx3xBj5\\\\\\\\\\\\\\\/htWAu8mkQUSeGiO6ije98y9nXCkJkY7O0UEYOHS+43AraQdT2sLYy\\\\\\\\\\\\\\\/PvG3\\\\\\\\\\\\\\\/WYLHlRNi5r\\\\\\\\\\\\\\\/LlK1lDTm1U+\\\\\\\\\\\\\\\/rRPsTFFRdgUI\\\\\\\\\\\\\\\/lfdDL2VT5wtrWYNOiMv\\\\\\\\\\\\\\\/Om\\\\\\\\\\\\\\\/LHML11V668JbXBU71xpp+3fUAARkLgP08kCk8IIpT+6m\\\\\\\\\\\\\\\/i7dL60H1bRLzSeB0ETw7psPZ4v2BRG6p9nh26fPruBFmSJSgdJmMMdD7lZsuyykLGvq0q6dW31StvBGeXlLQXv+RKZECqx7wZ6CNf6NbCL2fxvDSlDVgfEACjhdUrhbX1spn9Id4VpOKd\\\\\\\\\\\\\\\/4SObxadVx3rsdqXWEiqiofJRaxVf6oOQs79uclpQ+9zTPqkOb2iHmiTLBjWct94Dm2VWnKQmGoes6WMM54X5WMWJRNNgHdZrh8r4bpOt6uiDMcqTJ85mRu68Mb4SnqjeD9\\\\\\\\\\\\\\\/x1K6NgvKhs8rtYjxtXN9tkPDC4qouvRuVD9QSXyjE5DJq+ZrK4DNvY6p0pWd\\\\\\\\\\\\\\\/DKWbqFC6HNU2JEqdklCciSgQ4RxYS+n+lpLsYC7KBFdntQ\\\\\\\\\\\\\\\/eZu10t5NtgFD011JUHTDOtcHXfO6mu8IJbjE0sv0PI38HZcOq7aehnF3cS+7Kpat5v0vbGHC5vKvEYl0+17i5eL1NYvhWMYdagmgBpRHyQP+6OywFS\\\\\\\\\\\\\\\/5UZ0RjZO943KIzzoq9cNJXnOqEV911eyvDm7aJTCa6HJ0yPp0rHSRr\\\\\\\\\\\\\\\/F+daiht7NqQXDxHu50kv9EW62GrUWtHBQznHCKgR5sm+TdvbxjlLt0BMCYvqOlTEiSj+RYyR\\\\\\\\\\\\\\\/9Iw8TlJ9qUa5ylqvozkJDoWXMjK9lbM6igXesziEM608cdIZbbMumRwSH+Mvj+K1v+l\\\\\\\\\\\\\\\/EFucB\\\\\\\\\\\\\\\/EL4wLvaGBrTvaa3+nLkvjAjx3R3L83s3C3VspMkOdIzwUAOuC0M0eWdCn3N7UL9PhhmSbs\\\\\\\\\\\\\\\/S1ky4gOyrHqlh3uv16ZNlQEfNcpLHzWqt6Q7\\\\\\\\\\\\\\\/O5EbZ6PD9ldCkDMuYgFZc0zch7twAWH6mBgX0CNKTEPHlgrAwjJr6uCBBpumxYj4W1NPdfKYom75zDi7xeXaBUTp35537sohswT\\\\\\\\\\\\\\\/EkU1arYkXU7uwazWqUCeAxgPp0N3icOIm0GtO8HYdR2\\\\\\\\\\\\\\\/8yq04\\\\\\\\\\\\\\\/w6sONSSYbOu\\\\\\\\\\\\\\\/u3zDFsj4r+78oKyC8GeyQIXE3TiKrThB98Z\\\\\\\\\\\\\\\/gXzsp0ZoIuf7kKty5KouxEBmH7tPsFhVHDujzxpt6y2FsaR2keRH3+fJRSMsgujViZ\\\\\\\\\\\\\\\/q49ReQxnlmO8=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022baapKxBEo8M\\\\\\\\\\\\\\\/xy3rlSiBCw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00221435d9a70985fa27b0dd9e66f3816a5a2b9f3f883ceb0a68e04e6eb2a09e7090\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A872.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A872.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0775\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0775\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0775\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}