{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022noCqsZ3H7kghlIFM1eazqbXNzdbmSRc1qvOiN7aotp9kIpj+54q7vQ9VZ1FG6kG+ncb13tQ6SepCvieJpN2WlIPk2HdwXpGdlFnk7jibLQPOKyNMsUfzVirMNuqmOn2XSfSUjXT51Uq9uIyvvqX5vu6lS3+dnaIks\\\\\\\\\\\\\\\/gAEorsB2XCtaUYvgczvqgMtL\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/+TUwBPSIAdKaCVyeC3aDXWqcOsl8B1YTGVsZgJXFwOjR0PJzebQwEnEt2VWbZMEtRh3BoypOjzBnpQxYX27X4jLQPHoDO5pyzmOL4YjJeflVW6\\\\\\\\\\\\\\\/KDhmVmPyhWWtUkNnGbiTAVXz\\\\\\\\\\\\\\\/kngatWUvKiRRY3zEVgOtKJAG3t8r8yRWIXDKRbbeZ5GLlnvAzjZWpw7n3sAqxLtQrLN8XA1ygH\\\\\\\\\\\\\\\/am\\\\\\\\\\\\\\\/RQxDoPwR3LMqDKQerYvXP9t0\\\\\\\\\\\\\\\/pc6kE7TSjBOT7mTg\\\\\\\\\\\\\\\/DlfNPDE8gg8Zeavqy8FQOoDNkq5j2PepnnzT+3wncnTGS1eMWvBrDGLPh1tq\\\\\\\\\\\\\\\/Mb+Mq8uqJwRTJxJAuvakLqMAfJqOjqbj35Ezd4SPUNw1qmi0yegn\\\\\\\\\\\\\\\/W19cfOOf+aTAX55WWL0VVi2Sb8BNC3OHsXQEikfqFw352\\\\\\\\\\\\\\\/81pxuQqqk\\\\\\\\\\\\\\\/7yCCGSv43\\\\\\\\\\\\\\\/X+Evju3WEKr\\\\\\\\\\\\\\\/LyyG4ZF0qRbSNeBsePzvMLF9NmoyNrf4NdN+CyYrdqbZ6\\\\\\\\\\\\\\\/CGG9tCtC2\\\\\\\\\\\\\\\/uj3GEpf+1f1bEqdJkQGdI8S7531XIqvHZOCGFvIvC5GJpTuLYWdgdUqcp5qMtET88dDISHa8RxZbbuDLbjno8kLTST8lc+MUV\\\\\\\\\\\\\\\/yayuV5Hw\\\\\\\\\\\\\\\/AGHjfx9QXLV32xDWTGRQMWs8eT\\\\\\\\\\\\\\\/aAUcAePpZKZweH09DUIKks6DlU90G4vjXEivKjQwj9bng8PHbYPxtj3Offq86R2lSlrtztfKYFPFBDwOwKJSRtwraApu9kt82d3j+30ub+qTVpvFMCWn7hIWmo856HB9QS52+ma1dSbbd88Tlj8hSRQvc2FnP7Q2I6jHEqt6oLIRXMzV4Aa+CC0bJPm\\\\\\\\\\\\\\\/TXSP4Q+KJgSxSwY7dhIAHKfiBamSd34iNHhgcnaSMInvYuQHsyqxWZFz9um6pEv19mUxPjRL\\\\\\\\\\\\\\\/IVfbfSx\\\\\\\\\\\\\\\/ys9oHmGqUZk5Dk20Q\\\\\\\\\\\\\\\/LhRUTse21xH+jmoc2oUlJKkpo0u3sc4GwVaixgBfIUyyZxUTVIS1NuWW5E8S7s5BfoH0s+QNxLJRP8eluPHgJ7sNh0qvudJbBcVTgapWj6VXGb0b+Zs6viBS+7jr4x7LuB50N3rbYmOrZVr7\\\\\\\\\\\\\\\/rz72k7UdhE+b60x9YN5TAgWGMwkIvULdqfXcdC6YpZUH3NV57FVijETPyRE\\\\\\\\\\\\\\\/MUTMi38VKqxc8xEDJUA4dq6UZkTdSW91oHPtDIOnbgERxKSoBD5V44nPReS8b\\\\\\\\\\\\\\\/xWzRTLOQvUh5EEyI+jVHQR+xOrIpBuYAnkFpDmsrqgsIHeTfFqbOrGbhNP9N5iwpk3iqVjwzAuC1vd0GdeQHs0bRqkOASr10TvIAphwZ9u\\\\\\\\\\\\\\\/XnopOI4gsgWmBU3QLfTG6IIZHtQ213GwSPQgVvIB31jSNBAw4Z6TwABuvTAjw6VVqPr9pFqfaejuQHRbsdEJAr9FY4aSF4h6XaeD+k\\\\\\\\\\\\\\\/EDYsLzCspQvD1ttguE37HnNUaosrF1netcZRJWVT9gtePJNqqc6vG+qkgfY4qBjqxkXETNTHWkfnl+YyW6c6rb\\\\\\\\\\\\\\\/804WpzvpmAi2bQLAGfl9Bxf7EYEJveHROojO73HUTQBc8r04F9Zx9mqF7tZ2Pt0tNfbzXemHvpkOyX2vj7K28IIErywv5sA+5CEbOAwZQZnEPc59EP4Te\\\\\\\\\\\\\\\/GK0xD0lzDy7EEgoykPzCIjClpRkWca5OVnCu69SfcjfGTOkXh1DSU7TPVgthabDfdid5C8\\\\\\\\\\\\\\\/tqL3I3K9IYfbRO2ndBFPpLRGqih90HoHHxCAHx2TsivREYfcEo+zKi5qNPyJPrSuexK6GfJO00\\\\\\\\\\\\\\\/ER\\\\\\\\\\\\\\\/Irpn1x+\\\\\\\\\\\\\\\/M\\\\\\\\\\\\\\\/mA7bihKU6ozx8\\\\\\\\\\\\\\\/AtP+dUOVAUeaDY94zyuVCQfBbh8MAZmWRSu7hEEgl2JqnkG+YYO5P8JPsGY6gIfAiDmenCBBdvFIio2jSZetF2Wfu9k3fRtwSQisAvx1rAlU+W\\\\\\\\\\\\\\\/VlV+n16hQTXWGnUf9tcCg39+Jt7r+a\\\\\\\\\\\\\\\/kkfYx+ouyD1TYc+47DmvLBPLepXj721qHnlNo+l+y1eIP+q2k7HBT8\\\\\\\\\\\\\\\/Eme1B7NmmmcPzGF2CZQTy54Rm5cStRQp5CWifbAFr83\\\\\\\\\\\\\\\/gYs+mJsvmnyKQcE2hpCvXG4EprewAOPSH2YzDZYnCO56gN2OPJKhRnp0dTqGbIL8DrZk2alwD5tXE5UP+b+Htwpy6e1m1rZ6fwwhxCdzBn5sPNiPPr+2WPdKVyRBbH7M7isPkom1ZTqYQg3RjItP+POpp5TI2cmTc7ETOGRNK5aRpuUkjkBK6MDhA+NgTchMFgK7tni97vwCjwGyCV7fUz6bV7EgG4dXNBv\\\\\\\\\\\\\\\/NiPoxmqAZXPQtDMHbTpFJTSIoEYV96DWuFkdjxRMV4Ds9CiWBQxlZK49SJj4dtEdJ+39KQ283gdON5X0x6M+c5bRoPeqyWaywU7DbvkmcAL50BGd1cDhIiTt6H5X9cVNltFkryvnEiLaCU1ywFQOWNGGuF0hN0msCE47Pw=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022\\\\\\\\\\\\\\\/50gDW4s8\\\\\\\\\\\\\\\/wocMXHm8eCYg==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002295f0ec6a6f3719a170f90fdd8caf9b25d2ebf1e086cccb6c6ae0d57899a0110b\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1597.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1597.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1434\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1434\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1434\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}