{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022af3X9u7QJV6wtXT0kTUJL05sQNICXGUcXPEYhUL\\\\\\\\\\\\\\\/AYaNFxwACIRywDVp0uXVR4zHqU2F3F9HK25Z6LyzKIbCQFhLUqtIPTh5A79CqeZt8gfq1X+R1IblVBJojgRKY9\\\\\\\\\\\\\\\/faLlsCKFbyJbF1WzUzXSsWETCwuJrAVM14g0cBML+3NG5IbYGryY2ikyII3Z3tDcPuz6nedK5UlBT\\\\\\\\\\\\\\\/sWdhbrWFMIHwquxpAMI2oY\\\\\\\\\\\\\\\/E82G3xX0hw9f7LM9hXqxPVhpQznMBu9D5hjnIEs8ShdR1k7m0azcpJsvUuJ8fPEGog4DUy8Ptj7g\\\\\\\\\\\\\\\/uCEyeEe\\\\\\\\\\\\\\\/pdz7byteDrRY\\\\\\\\\\\\\\\/FQm3NwsSVEExNpqBX1+ion\\\\\\\\\\\\\\\/9kfMW00o1kLqHuOBofSAo2FP8tDU\\\\\\\\\\\\\\\/ZjppdJpGpE9u3OgYyeRfI49QrC+ITwjBW6M5GhfLsqOoOc6ZVkQCkkdXnJ+Cyy9ZHPG4WHTUhR0RddnxWvo9Po7lwAJeA+IIJmjiV+Eohym3abIRFUyksqXpjzqkn2bs5\\\\\\\\\\\\\\\/7GbsPijmuOubIWFN3\\\\\\\\\\\\\\\/sXUacvi6cqxk+YPeaOLkukJeJW+8\\\\\\\\\\\\\\\/0BYiGYEkYdX0fm6G3Efomw6HOhlO25I1gtkamUvaIVsoOe7TgaB8NqbMvSWXI+X+ZNVISlaTeG2optUUuYbYcc1NL29MxUPaAU8qedCMIDMLdu+WHZQz9Cqu1GJSCb8n4HbdsV6pq\\\\\\\\\\\\\\\/ytJyGQrW8p\\\\\\\\\\\\\\\/S\\\\\\\\\\\\\\\/NEeDtCZN\\\\\\\\\\\\\\\/CufUirGUCjSwZxUSL4HU9DXHSUq\\\\\\\\\\\\\\\/RT8vYsHMj7ftADdmiNHA8TqlkGp2FeoFaYbOWCMduF4f22gGUvboLKe3pEIb9+nDqT+EMG3ulOw8YglULYFkEHvT+BtHPyX6E8q1EtOaykEb4Y8HgllT8niTljPs+22pIktQ\\\\\\\\\\\\\\\/z0evvNbRRuA+KuLUSL4lo2Uaa7wkcoqGzOWbXuDTNTpHsDOe3pMY\\\\\\\\\\\\\\\/F6OoGJJVwGHTYjf86qbB3u3KmZ8qdOB3IvZJsFBhE3GfbMws6uMbXRm8bmGWEJ8bdVPYnzG51DPB6cmS5P8QI0a+5hpcy9iubLY5+gK8++M7Zrsdc3tnnaStCukmGeS51m71f9BmC126VJ8q2LRqp\\\\\\\\\\\\\\\/NZ7v2hsFL9sjatSy55tq+mXww6aV\\\\\\\\\\\\\\\/uiG8XSNrkYUWk7f+VSOlwMQfC+pjZL0E4oRjIPsSDRpfc70MFGt8wZl022FBL+RYJKc9X3lh5VR8NyvZmyzEbvHJnFA\\\\\\\\\\\\\\\/VcG\\\\\\\\\\\\\\\/keTA4q763\\\\\\\\\\\\\\\/RXXbqvOXN\\\\\\\\\\\\\\\/u3+PRReXrtrgmts5uRtGoJh86bQeMG80ZlrmnMuJENUWNp\\\\\\\\\\\\\\\/xsQprKXdZVBbTeUcVWqNMaun6EE+ke6re2wHTpYHhVw77MmpSrsNMCB9u5qBb\\\\\\\\\\\\\\\/5BPn6ch4\\\\\\\\\\\\\\\/qqMYTEeKRC2FhxREFUtfudiH8w9QjuyfIa6RI1rwg57uCJRt1vPCoP4uf65mL+4paEbMGCUXqHc\\\\\\\\\\\\\\\/1yK3MUHaPAy59JQBOtbTegTPSr8nKyYxrPlIxK\\\\\\\\\\\\\\\/QUzkU5omxlbJilpRe4AGuGhY0Q3IKV4iZ+2QOlIGtH\\\\\\\\\\\\\\\/10RsRoNG6OH65yhYEy3FlosmIC803BRAxuOYjpg9StCP+6TsnTQuNYFIUDZ4VFC9FeuTZpZLHNDBURbqiWXzRZNUKwUw1fuowvfpIvxUdps4toqFIj7NcqsAqv7eKHuSd42yp8\\\\\\\\\\\\\\\/DH1X373vy\\\\\\\\\\\\\\\/NmGDtbLmzVyslsh2BII61HTP7TwuQjmqwMT4VVbjxd3uia7YsDbUFvrjBeOHcn03v8BTY5VFpz5CY2XyK+Me2BapQ2ZG2WC0lvT8inFU+u5AnBavUAiewU\\\\\\\\\\\\\\\/TtVCdbgith1ndv7xis6qTusTL62R63mo0WXSglDlNeN3A0vOGul2mlfHOsUhhoDaHAZBya9oL7dFxRZmwQ6ntlfEWXPBaOO1z4cthChKZyWlAsbPS\\\\\\\\\\\\\\\/c9ZO2Afqwoq2TxPuwuxd3GlnuCj+bIwzGuFYxg8srCZATd\\\\\\\\\\\\\\\/p5As\\\\\\\\\\\\\\\/2XWPa3vUflGhODQHK1l5xopW4bFyBjRTY7afvs36frtDS6PXRjJQZ5g\\\\\\\\\\\\\\\/uqxELAaoo69jYnbVpG1KT32B650xrHhr\\\\\\\\\\\\\\\/3+w8kbtKSSpZMWZ+bOHIb3fTbTIFXwvcJYbgVvVepKh2nh13c7qKSClLqTkDtdMDIGD\\\\\\\\\\\\\\\/Ed5fPEbiu6oWDP2H1sT7QixtDHUd1\\\\\\\\\\\\\\\/uydVRXr7bzJRrXYn2lYQwMPfBAjWsgSnv+SqjGTUBW2lSffQ9\\\\\\\\\\\\\\\/KyyYvfcGIIm9x02rqfQ1pl5WbhdkwXj3j2UmbZr1cILflqnPVBf+VmIdML1QTZGVW1mqM3c3C3taVZhj4QjfQWAL6dZIt3XookMMUIB7H6R+7eXpxT1878QmnYy6hJdoggtCzEdo4qsuFhygNVV5JJcVb\\\\\\\\\\\\\\\/PuxEZkcz16+9dC1FjAX3P9jphkISfXyaJJpW7HOTGoAzO+yXbsZkY2Xs7gXSnMRaqP\\\\\\\\\\\\\\\/DfKHfimWjWkNdsHwXfRSwmvK8ncTnuI99ytH52lyqZjr5VfM2KiygnB9rJlUI1gNNH9nRasC1Yqyo6Vd5BdTAU\\\\\\\\\\\\\\\/LJYJfzwT5x3vRq1NQ86E4bAGu1FXcVTefvTbk8L9YapE5MDubcX6YNqr4xs1EPlJZt8lq8vx34Nm4ltsHCiWIfpIbJYuI6aqjX+w7S98GO28DChkV78tgBf5kKWLrNoQ=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022T2xyHvUrh4KhQW1TqpEacg==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00228a97dad6b451692cd71fc1dc5292cc082b50ad0dc1f6b496f68d96ac821c3d13\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1597.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1597.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1434\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1434\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1434\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}