{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022ONaamzQXpuGl7KThQaBD2U76fbaTqK54oXdmYQPaQ5dHhPFuVsPhRIkjWsJKS1q967DdPexgEamwXIox20d2ANW9RMDZ59J+Q0Lfi1wH5ysfANtc9bizKa8zw00887SnHnk4fvFiQ67ZPV+3HeUU7QAetImSMZ\\\\\\\\\\\\\\\/MepVPI+u5YqDuMBokEKPCZNj6swtIvuwlCTkgRgwbHkwdLLp2sCDxmTlGZw9GPDjkJP23yjHtR\\\\\\\\\\\\\\\/x5ea+KQqWVxDDQCXqL4O192tbS+v2pblVEY8HPKDqsh\\\\\\\\\\\\\\\/fN+iVLFoaidNV52s84pa7acP0O07mWP1PzeokhuS\\\\\\\\\\\\\\\/XXDAD3PMyfHvM1ezjKJInyLp9mdDlAL5JnraU41dOeXhLdVSQ0O63T6iiqJBKR\\\\\\\\\\\\\\\/dxMN351r7BOIskXjt+J3v\\\\\\\\\\\\\\\/6A7XBZGqPQyXcqSvTQnSHDEKcA9A1SnoJmlPDYX\\\\\\\\\\\\\\\/u6NGaCMHznDS3RTkijJ13vso1S5lgbU0XHPrJR3iRRL5H3+oGgXGoRxDKO84qoZ4Yl57jzHMbdciqvlAKrlblWXYqz8R6eQSvq5M3BiM9ygVJ8CPcmMelb793qo4Cktz2KlQd5UhGfyL8aQCrg3m1ws0BwwgIHM+3tXPtGZlbAYC\\\\\\\\\\\\\\\/L0rcoDHEpi+UC4Yi5K+ssmWRkw2zyGpVbNDU+EOcW9xx\\\\\\\\\\\\\\\/tD9b72WOwgoJy6CveFtafYeocNrjf0MCLBQkOpj7Wn+eMqpwXf5zAQIkwRbnLHA2KTYUzdzOH7bf8NI22I5ALJy6cu3CuwbVT5LFT27A8OT9QHbuRYHhJxxEHzavGpVXo1NQKddMpRkP48FElYRDCEVAKuTuyN+chGz3WQban0YyEidDhqUVjOgq86gySaq2ZTWGrSTdFjp2tEMqHh3+UHyceE2El+8vbFTZJPzk\\\\\\\\\\\\\\\/2rQDnoWrYtYbsVss49kHy0VOTNAJEo48pLE6qhVY+5\\\\\\\\\\\\\\\/OoJlxVsB3BY2nMcjc1emYBIHh14frpenPHiLOXSTd4dqzthdzXY0Vx2VzLMGvMSKl+ma\\\\\\\\\\\\\\\/x0UWngqgovhEsg+\\\\\\\\\\\\\\\/N4Gs6EN7U4Mq6W3GAHjbiXdFsGgHJreoGrpCRPZtLXv+nU\\\\\\\\\\\\\\\/6sS\\\\\\\\\\\\\\\/Q6uoKdQpmCDxrMJ7hjj04RwOCocfUwidlEEpH0TNzu1TKYx4BvHvQB2tgkUHiPOMP5xm38wpE4KTv+QugucwBsyKDy2CadbEuFc5AI\\\\\\\\\\\\\\\/stGqyv0qigjjjGSeil0Ei0wjCrR0dqmc7m69ZcD5QTGbVK69UYgHsg03\\\\\\\\\\\\\\\/T2AK6+3+BNAMHKd4flV1JsikKghsPVt8pwW6FGs8C07j+gzriXJL+veYvXjh6kdbUcPMbCMH1gvt8P+m+JXY1rWmx+IeVaWNnxu8TavemOzMcLfw7YPPtNUt5ZSTdw\\\\\\\\\\\\\\\/cZwklrKJygfC5zoE781brm\\\\\\\\\\\\\\\/sIN6LZofm5aZDbCT5yRtjvXCIGm0596w41eRTKxJOdPdJWkUFnqdu4cYe3lE+KdBSVUwxhH9nv0a2jqmojqbki4ua8VpT6a5qj6ipvjKSAWmMzQZqQv41HtMNlr1XAolOmfDoRMLo4+PuJXwouAwPD4dTE4Yskp\\\\\\\\\\\\\\\/xXwH7QnipiOaBeSMCUTRGTnq+G+2rdB5Apy9WBtKq5JhYVM6oG4lLyD8NYfDFSLv6uqWeo9b4VuYS0Nafs2hMepWJJ5RH0tKt\\\\\\\\\\\\\\\/q+DiADOam2SjP\\\\\\\\\\\\\\\/WC\\\\\\\\\\\\\\\/oLkuIZF3ZbeXzd\\\\\\\\\\\\\\\/ETKY6\\\\\\\\\\\\\\\/QoAohfcDRvntwNI6SneWaduY75wTgPxM1TbwLzFmYZCE5a29ifgnlVN8i0hueuEZNs94cEWXjWhBZ3DrqOt9DkPEanm2CfRyp3sMaouHKb9Tt8f7lzPxzgxEtTcV3yQbjsD65LPrWyf3LeMeqKKilIcBoT8NTh\\\\\\\\\\\\\\\/6fL104ALdRwqLJBPr3cXkg\\\\\\\\\\\\\\\/S4uSzHvxZWZf6GFprm1tD0lsVzlMfTwKwOAsekFUQONmS3M1Y7k4XPgJLhhJ35l+E2Bq\\\\\\\\\\\\\\\/mvjQYT65PrCGMctnMyhIMcnesk+\\\\\\\\\\\\\\\/tXFOV7aoMfiC4DOMS1Sc4KebB6kIfmaN+3dyg69x0wRQFrikDBAx3mVzfSq3KSlyCeI3Y2QReYBHJ2IcePsuxkCm83Rm8Ani+5vR+zi37D25rx1BZ5mR10NT\\\\\\\\\\\\\\\/dqEcoXELkMpGDB1USTvw41X35ZYwdZJrzBL5U5WbxEKajfwXFCzWmetsFdvmEgHihUy3c1LQpIjUj+K5Gfp6\\\\\\\\\\\\\\\/5CNDqPWKe+JEu9ThPknXxE29+3bnJK2udsV2H8g4a3Bb83aA6V9vwJsKtjZy9wOBLHUWvTOMZEsZh6GfPjo0oBUhUFnmhtrH+ANocJaIMtoEJOzkGFPl923ee276xH3HCAQFDU5B88P6QTo0rpXhO0B9SIXYW2W4Pc\\\\\\\\\\\\\\\/CUHTZFKQ\\\\\\\\\\\\\\\/HrqJ5Qfbx\\\\\\\\\\\\\\\/JYYqGAD8cYVR1yv4CSlpUOo5NO9VURQTW2D6T+irkNh7+5bxHtnlCf6h5UOByGlvrrtH8mpGvNAFkakTD797IT9GUeIvQfpJLigCCe2fxZgtg9GnQt7uEqp3Krhw0uGnpantj+xojquHxXBRNKMcjWxP0uXvAdgyRWObHoU+e0EEF6sDRtUjQyQfJvXQCpe4AyScjHHllqXPanxUAFCYFRBGyqKz+UQXBn6FTP9w+Up4\\\\\\\\\\\\\\\/LC++L\\\\\\\\\\\\\\\/qFQdM49JlDpjM=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022RwCZQmiUq+K5l85Fb1SWkQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022d0486c4ec325ea7be1d23b683154b092901cbea02f146763f7034ac87eceb32b\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1366.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1366.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1238\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1238\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1238\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}