{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022vbOB\\\\\\\\\\\\\\\/oMAZGyCCy4rJMqDBPDkHyHzwtPJ6owyaJYpEchuzYpJGoiPvb97w30vzczvVTmiBgRmvdpuScYFM0xPHnbD+RbA56Exns4A1KxJA6CHhB82gJ+cWdBLP0SVWLNaLQ8SHxm9jonBOmnpcfhfGH6+c4E7\\\\\\\\\\\\\\\/y3Ro12dNF2EoA48xoigZnlYraEBsfL\\\\\\\\\\\\\\\/j9lNb2Sp6T0zh22X5IrPkyPkE3sJmOmrGZqnVYXVnEGWePP\\\\\\\\\\\\\\\/sVZKOmAoRvHGwdDJ9Rbg4p5AsADj6inTHWod25dBsSzahT0tAX8p7wayCiV46CUp7Rymfc5C2GaPx634cG+zt0j23JvwoMwlgf6U\\\\\\\\\\\\\\\/L9sUQALoqCFJxGkoyn4PG\\\\\\\\\\\\\\\/HONyMTvos3RDLglMw4A5WeJYMel6IOTmPfEDHKT3xj2rbFcyRwlq\\\\\\\\\\\\\\\/zwmKrSt1OJVnR5iK9q\\\\\\\\\\\\\\\/jIOCQrkREbru1Ey98zb\\\\\\\\\\\\\\\/BcwwxIIrhihUYeQ8AM4YrlwdoPKuUB12kHWQX\\\\\\\\\\\\\\\/ycNRWHbnE8j6xEp8HDXB5xuxBDS7bc4Kc1VCPxnH0zbqvOKdVjghr5PLOnGV+\\\\\\\\\\\\\\\/Ip\\\\\\\\\\\\\\\/hRTTFT7DCHYKmDsp2jYc8XAX712Gb\\\\\\\\\\\\\\\/dssqZ0XnxZpwtYW3Fq1KOJoGC0HXxPqgfJZ6uORe5HdbqADyEaMTVPW0vQeuFnIHpaYfrI2+yQ8q2Gze8iYCVX6aatvZYALRYNhzjQp3Bcrj7lBjUaHlASsZ0UFd2BlNlvznQbrio\\\\\\\\\\\\\\\/eXUs0n8Lp2iK+SVHTqkkkG7NvPZu3NmDbzfkocEzjqvnC63wRLHx2LmKWYefX+v0Mb6GxiGgJqFZlrfmqlCJGBvSecXhfQivMzZ5+DIxrivvnAFOIRqXzRepK5riH1phFXv4D+00SnulUctmXCkEA9lS+Abj3dUKnUOXPTRuvH4BiAXLAkjgrFwrRy+AzDoHD6l9PMEVd+y+1FsM4u1ZpqKIGVqKXZ4H+cG2hKGNn4YI\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/cMQi5pYLWwKGgVcvSZ3+IwOC0V3\\\\\\\\\\\\\\\/00VppWLxc44OhU4aXCZycl05LsL85xUw28j+MOsmDIeuQ6nG+EweDtoBKnG1gaGS7iGGibu6ldrBAoJb935UMi8cbCNoM0nc\\\\\\\\\\\\\\\/Beo+vOhMeh8l\\\\\\\\\\\\\\\/T\\\\\\\\\\\\\\\/eR8XSC3c27huGcAYl05zaIi8PQnNCiJbF225Uw24JuI71lYMKjmvEozhmUTfepGycBbL9OTmEAm1NPIKBVGFfqAq4Lac1NnJtSiTlwakY701xVJoj3iiDNcuETkFAUXMq6cRf7sLsDrFAE9aKGi3caKyuEY55v21BSUa4gzuNXeP7BCPvY776wVOoZBRCziO6viol+l49iCCVZFA5yoxfWlRIoH\\\\\\\\\\\\\\\/q5RQPjeh4vZMkhStONWJIxsXwQCA\\\\\\\\\\\\\\\/mDkFLsjBs6DVNhqy0AWM4af7NapYIGAOO7fddyDrYWXTBpBn\\\\\\\\\\\\\\\/1\\\\\\\\\\\\\\\/kbdvqa\\\\\\\\\\\\\\\/CZdYeE5a55C8wH7sBJRTLKkud7c7rGKzO2ixBjbTk7fxQ196NQuVrSIWcpWBlGsVTu9ZPA\\\\\\\\\\\\\\\/4Bd7aaj9qQm86WScvpowelKqKajlpaavRNMAp\\\\\\\\\\\\\\\/+ymPDqMSJg6XMhAbTWsnN9805klKlQT+KRVnTCLTisAVSsMivFDgmog+UDlcMfxxpGxbrKENzmB297NiBlUxOnTxa+Gw2yUngU1VU0gPZ5G\\\\\\\\\\\\\\\/Qhl+Jy31pE3f+P+gbtTgWYqioh4nlQsT1UTu1G74wv2vrvp6uR9ZkPOKcOszV4MYbmV67CjOgTvKO66\\\\\\\\\\\\\\\/pRqsWnLCLLc0WVcZVZc2iWxeegJOsGJ7cMdu7RilZkuHFSaoU2qxGBSVqSyzf5awzlsm+9j4LlIeZxfC4slszLGsXOpV7O2h6OIHhiR4iTw8KSjSVvhzu+w0FajsUHmekguudDYth7A26oX4wV4lMWjyXN7sRmMQTTVahXQb42uz9uQWIfKjUNZvv0O1rDzuR2IDrpK1\\\\\\\\\\\\\\\/rGpAbPB3XpLXkm3cfmz03lrtl683145yc98QO1d8IdTtNMq6WvpmXkzYMKGe+wY3OvxtcOMfGZIKvA1NOq+VbBNYMUG0N+a\\\\\\\\\\\\\\\/whINylIKdnmyKhI1QNTpKny78Qc8WiyzkD5z1jt7DFFyIjFtuFVNsd49SmfrSeiN\\\\\\\\\\\\\\\/dBZzfLR5ioukaZem7bDSncpFT8vnLFKtHjIvYynbsNyqojK6SNtIUzcfnLXkZNA+xtVU6AJv7k1pfcshZtb9yHhHvajkOaGJEwhYrzYVwfBZM4EFldAD6NjxuqvxD\\\\\\\\\\\\\\\/0bl2aeSV2Uku2W6jlnSXELl3gTP7qt+hsoxpCTn8ZRdlGsCJbiw2A85tTIOksLz2A6PiJ4D8YJ3E76Wtc45kouSyD1POgE8zp+N\\\\\\\\\\\\\\\/+ZkU30Q1Uj511Fqf\\\\\\\\\\\\\\\/RAhuSjuKtqAUBVeE3Nlh0FH9mILPJMzvqKmbWN8EY8snbtEIP5p0rOvp2Q26nichPkqxjVR1XM8fmmO\\\\\\\\\\\\\\\/w9o\\\\\\\\\\\\\\\/UrGAzMj5BKngLWRumLBQzDlIlqiW3cOIu0+QLo\\\\\\\\\\\\\\\/BnDVYdKt3qBaDas3A67pfqBhhSzmbYhVsXN19CrQZF0l\\\\\\\\\\\\\\\/MJby\\\\\\\\\\\\\\\/to5QZ2P71mG\\\\\\\\\\\\\\\/ekbMyPC3SEXH51vePNLmwKN3YqrAsYLaF968HClklzRbfWyNg7lrZOE6i6Zyi8sqBHO2qunxqtdeKb0w0+9Nj6404dmmgV6p2PQOM0YK0SzjA=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022pftxKgnbfsCZRHfIyneoQA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022fd9fffaa035b1a6ae6e525e1b79c3b268db98d7549d7540f045a56f299dc8db2\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A792.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A792.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0698\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0698\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0698\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}