{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022\\\\\\\\\\\\\\\/tul00\\\\\\\\\\\\\\\/wCVhsKCGXqaaWHfk6qZeCGy8oef6ej0gotcQ1I\\\\\\\\\\\\\\\/m7wFIEJ79W3\\\\\\\\\\\\\\\/Uo3caEoltCSllxdZpmseIoTam3pcy57NyuiFiT3S\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/tjNkNayIS7kVFpn\\\\\\\\\\\\\\\/NFDEecDNsQ3k\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/VZhqZDmHUOQtLmO5GUtLOuh7Q6FEFqSR3zwcJQjbvGsqTqJPjXKDJ278XsRA51NJO75nUloFyTD9xO0eFzgxSQ8X7bihQMzPskHujdaFlv3TX+vlSJ\\\\\\\\\\\\\\\/hPRWa7zaef3KpV\\\\\\\\\\\\\\\/3vS\\\\\\\\\\\\\\\/M7PKT5jMpGljWC2O3rsKqe4+wVbMT095fNS+xQBGZpXfZ5b755HlgReA4YrI1\\\\\\\\\\\\\\\/dTA3OhjyvjGf2JDAll+Mq2VOpbmdhKcoAa2F4tGky6kqCcWxn2usKApi\\\\\\\\\\\\\\\/E9Sa5nQOFz0wBKpxBDbeKZ04yHn6qt1v8XUS\\\\\\\\\\\\\\\/hLaX9rVe+Gtys7SqPS9Jb6LuILax5Vxp5H1W\\\\\\\\\\\\\\\/nla6nFNV7Rr6i2BY5ZsmdVLSwQpukbgxqLsVluqOtE1ew1x7rO63DUARsstpLpRHTJ0vKpvAAX2UBHjSX0NhrkmXdCheui3+A1Xx6+ddOPbBAa7ByQCl\\\\\\\\\\\\\\\/cgV\\\\\\\\\\\\\\\/xOm01wIsBCYpij+JF5p0FdTtexlJY+5aKZNJpCz1XQBMJFEgDwZfrheJKnNO7V65nRXiiPHpKx\\\\\\\\\\\\\\\/Keoud6ejUWQ3RTebdpYERGzVvgx4oov4KKeSsJc0R8SXT1LUIZykk76eh8YfQrp08l0oZ5hQ8d+3vi+3gbjunJBCK8L9E4u0E4U4ktoHDgEJXUdc3FSL083KCdPWxVPYLjnSuGSY6nz4loT3GZ9FrZYTtn5+WoMW2vdYJk8E7Eo+zyvwI2ecl2PFdC803wwS7KSK711ZM0x+TLctlgARZhP1BgOfDTKTR6DQfQbQOQXyvSMpmmZHTb11auo0VkmKfhytQA4DmpygcgnSglpf8lLos3M5LfcMgnu\\\\\\\\\\\\\\\/HoNzLLn8yYoXf13nEJ5CWYCIZjRjtP1vSeHWLmbnxovEDzrDtP3te0aBg8iZMg0n392dZ9agkzc9L+OxwSRTadYK4RvtO3Mtw4m8wRHjU+58X\\\\\\\\\\\\\\\/+adljMy3SWxuG8YMCgIRUEydqUrLIq7aNFxvvlawZaJx0Nnodsb8IDIwXMVl5SwJpwuAaSAZrGfWTFoNhgrqd\\\\\\\\\\\\\\\/XO2qSddNNFTCkK3xYUj8bV8kqUpkiqv9iZe1\\\\\\\\\\\\\\\/ZsHbdlxp5UBBAINAMyLlFXHGI1+vipKUV8VHmE75e2ZaKJvE0cCp9g8dkP+op7mkc6+H6VtoMh8W1i9f23Dd4XxNAmTGha6QOCdbfKl3OMClcJrSdq03eis3yDw8qCX+MRxxeBH5dsqeKTxI20+nB82SlgE3mxDcC1ATiPTTXXr7j6ozZkL9j70ijwXstoZV2wqmsbAQAndApVJubf75aryClqlBpFzHH81hFs7tRShbPRg8NHjUPPh95gIWA\\\\\\\\\\\\\\\/NZTpLYdnvtnMbAX7kgOeRBQlEgGkY7kU32l3M1Z55ZhV8E0+PCf1QFAYjKw6cbSD+iksysBGf8M49smLlk2YVdAMqhVI8R2d2CVTxOouB6jsJWMizTGNe6HTBHcHw3WOQEgg2jpOMEjZIUy0CKH3xhxQMnXCkhBcHma6zwZNd1+BVnrpT9KFXyYGvUBT1RvYmobZc0mbcpMEEqHOsAUakx5XfFZsZXOyW\\\\\\\\\\\\\\\/qC3OYmTstTpPY43yMRHz\\\\\\\\\\\\\\\/2Dll5t\\\\\\\\\\\\\\\/BkOuL4x4gfv51jhIG1VHP0rT03lpbaeDMAiSbqPkNLqT5HPP9JEN3eVh09UqVw7JVvKXcErj48iv0XAeV0r1hxXA7CKJpm68B721vy2N9VoAWiXJuoYGeoD+RFHGHOnRY9zTG8a613CKzUlnp2Y+mek10WMcNIzD\\\\\\\\\\\\\\\/pSVOXnVp8mtHSoMQoOAX15nSD8Bcp1Mz2YDmJTqxaiPpl\\\\\\\\\\\\\\\/5109MpnLTZIyzFNFROuBsoOWcLQzMfCXwraXglS4H1dr4baJTQRriQFF0VzKjG12yfvNpscePiLBNR3fpeIYYQwqPfgDzecpXpW2XEYTtVTdUA8OHnRwy42h+yzR2Tww4HpyhofzqbzqyJFV2Y5D5IlhbWxzGoz2BKGLhXQcYBSTtprMdsNT+XIqhzaTfDSi5FuaEd81K8JsLTFSd\\\\\\\\\\\\\\\/VllZpd3myVyO3yW6\\\\\\\\\\\\\\\/8iqZk1QU6Xdm1xFBv0QA8WtX8arAC\\\\\\\\\\\\\\\/fC1+0sZSOmxYMiMvZ5KnpVl\\\\\\\\\\\\\\\/tevExh1DW1QZniHKoJFTR852cF9F1p3uWqQaplN70gr3IDimuTlbYXsiM9GVPxqSe\\\\\\\\\\\\\\\/OR4Duvi\\\\\\\\\\\\\\\/hV69r6CfuJ12\\\\\\\\\\\\\\\/nIDA1WFr7uOPBmgqEa4saMEpHgSIxXHyogl9Nz29KWc0fp7oqqSdhjFflN0niQ5otfv4B6fj2eQHA2NEt9TASga6qkvcrWUnN+Y2XWRBmct\\\\\\\\\\\\\\\/Ob5euUVPg9urfCe9OxXLP49YDFPD8xjYS1vWwQUtWM2YsMefjsaFP6Mxyu2s1KQaCRf8t4uYW8FR6tmHNCqK4UG6QAXNYXtczg2KyzBprvQnihMOLVLDGTh31J\\\\\\\\\\\\\\\/YmNCxslcVB3lrPI5KgOvYpzcvCy37yKUhKCPM0T9WI6vgUUWNp0OnEOs9kG5eS9CW9zKUBHc\\\\\\\\\\\\\\\/2ix9K8u\\\\\\\\\\\\\\\/1lPRrTeX05kNpQgvY3RtlEefuTF04c=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022T0wYQFiYhLZrZhLfk\\\\\\\\\\\\\\\/BFwQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022d036a5b81255a10dee89fa2f2503fdbf53b6cf8b9f08bf062d6ab5b39d7bc2f2\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1284.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1284.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1165\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1165\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1165\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}