{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022FdZ8x\\\\\\\\\\\\\\\/MG1hqEHlk6yneTFLT0ECqd9dGFgR3ZZW6ylfMiU62Qf7vTKQFfjpT1+er0hAQ6Dk6C4AQviI17mRhOmnjI46T5DJimTcQMVI1t4P0j+dNUcIZNICucav6YQO1ig5Ckt3Wg3jTuTtQXX7g\\\\\\\\\\\\\\\/BBBMTZSCNx0AP8iWYXhX\\\\\\\\\\\\\\\/AJxX8USN64ogoZ\\\\\\\\\\\\\\\/A3xmgLCafSOjev0xyckiivI4ukNPhJYgWPkVK31IEjtuqQWP3FgU+rH3CBKn76Y1f0iwRDlQ61+68VP2KADthj7rbnOU2daG+eF5pIqutXRRj2Y6DzedavDtTsfv\\\\\\\\\\\\\\\/g\\\\\\\\\\\\\\\/w1hMLNBalrpYgMycEqBmAYAPj10w4+RdAkU4KfGC6YkUS1EuY1vUGOyiAqYD0t2Dy+SLQTUOZm4iH4or7QDjB58g8f76g2ND0UtF\\\\\\\\\\\\\\\/f+NuJeCpVHRHbPH+jR5Lxt0TU1hgoyJcsxmM8gexSwriYAGv\\\\\\\\\\\\\\\/v2lFCyL5fLtHyNC1hyCces5Z8Tgdv3qhT77e8O1zs9ATNmuPE44XcyiQRAA0q\\\\\\\\\\\\\\\/ZppHA1AymZiefyEcfG8H3QKU0rZSnB4pw+vNPRoDDHAHtBJmEd8baA74JbcUjfhuQyuamIbVa5N1z+HfTARMD6SFLk0SrlCjiBaD7YufJ3WWJxUDq1R4rsmlBmA3XO14EI2+CC8\\\\\\\\\\\\\\\/oQhjH7Xv44F\\\\\\\\\\\\\\\/Z0\\\\\\\\\\\\\\\/YrPuLfpE5z1KTNi3vMbs7QC8wF\\\\\\\\\\\\\\\/LKyt+8Cvze3JxEhkXDuVWg5iU0pPuxNlz6v4cIscOBSaPALrIEkm04NbXr02Z+Z5VCJGGh8LND0rd1yZl2bHBKdLiVGDLvCN9cbXKozKcmPlmmaJBihb8+adqyfgBHh1t7y365UBHjMZvmsHTecyQzgZbvEhuD0tdPmcYecCokJw55Mtngr2XcBZl1zX\\\\\\\\\\\\\\\/rqXi4adeXV4a1FirLyC5tV5QBi4yV3kbF0e1AzB9Z6FPfRBoJqC+hf2Qq7SJzSbIRLoyST6RlAgS8qtZ\\\\\\\\\\\\\\\/vu1xKUSnQehzlIXDjEKt6o5wNHvPzHqWVYFpUCdtgQCwWv4Tx9JP4eHe\\\\\\\\\\\\\\\/Xlp7abo9WtWsBmmalL7d\\\\\\\\\\\\\\\/hCACaoXaqv1z+GpW3N\\\\\\\\\\\\\\\/Mo5fK+5HWMJdlO3XryV\\\\\\\\\\\\\\\/SeyOZKYiOOr8xQe8Y+YoV3whVVjFSdrMFHtK8OfG\\\\\\\\\\\\\\\/cQsMFFdHtlefJFA7xaCJz21aHEYJsk5XCH2djvkgNfXFFgt+VLNMS4Q9lyQHzjlts+E3d1fYJsQ0vtIYZsw82x3kbrrHVjyElKtoehUoufCPaAEj13p5b2KVbJtNvsMjsdVkqSD3zaud74a\\\\\\\\\\\\\\\/yQ57Ktynq3j2+LEqTXMY97ykeZfcZgyn8PSB4Laq\\\\\\\\\\\\\\\/vnkSlCoOId9iav3a9lVwEl7dsIOL0U8atDhP9QPbyBTal4oMgJP+ZO86RO6ycBNdPaWBnbKuASe7efWi9UiMR4BtmnANxF2kKKusEAp5k62l821I6oOdQ2e2NpUSo9vCUBmk\\\\\\\\\\\\\\\/dw7EJcTyQGe1Afgse991Vst31mvd3VatptriSU1HwEPLw+L4PRXFVPaxAsxrThcrV1VPSqJmEbtjXGb1yH3S7wGKjDQ1YGuDjnfiHI3a\\\\\\\\\\\\\\\/ZJw4uaPiO6vZR6g\\\\\\\\\\\\\\\/dTjEvzZC2hscQfggl4OyFf4WsUgAXH8Ehtmatt91JgOWzHBqP9CmUgTjoAx0v1fm4WwFVcTa7bIC0f3p+z+AgHYHVaxC7cJv4HmNJXcLABDTLZtwXqnlP0xrnTayhrSZCdn9LB3f6gzrowIaBrbUhJURsImytSWcC3pSqvg5mvOYi4kUMS+oI3kvK1EFV8UNGjDgovaZ2crY8eM2a8E5Iy3ozfON700pg6Y4BPYvJEfdvcEDyb5mZjTCH0YFpfpRXOzLrXwCx1KABhXUq+XEy2e3Faq2TwnErSo+34fAGR4GY1ciXI3NUSlCdnCi91fIDbAgjfYmtJmlkyMS\\\\\\\\\\\\\\\/jGjZx0V9v6t0Rh8u8gICdxL+HJfirrXnAg9Sr2TzlJ+rlrq9av+\\\\\\\\\\\\\\\/0mNKahRybfblZRBIp5B+BqwNXVBG6gbjK+hxQ+FfD39rSExyd3R0z1P8nD4FMnWbxDjeo9cdLXu3pGUo6mPXpNDC4SZwPURsFuooiSC4fDvYoF6XIMBvnvE6Kr8gw9S2j5H7IoIJc2pa\\\\\\\\\\\\\\\/HVA4cqAHhLDJ4IGNMbwc0s9F7RAcWfnrblKo9+9eXMVGBm7LxbfI\\\\\\\\\\\\\\\/SH9Du3VPZr+fzUCQN7jTpj5HIthfkGlbffLFPnow55aVSfwhgiITTfnNlL+0Qy2w2+5Qu9JQnJbePVaULPqdtO9SWtM+gWoist90w4oubdoVRrj2FGuiET\\\\\\\\\\\\\\\/NIz30sH4zUg3BM5bjLa74wvC9QTJJu6GKbOglDQ5yVtsym\\\\\\\\\\\\\\\/daNK8pjaNVddLkqVpJMlU2\\\\\\\\\\\\\\\/pZgyf1ldPMqHmJQuLivU9HRZsPFspJ8OGejwLYMK2awLJ1w3QnfziVEoBFeYMQGm3Ggi\\\\\\\\\\\\\\\/VNUx9pigAbf6PDduGG5puNpAsQYsxrDh8bcV1Lhit8NSl+TBC\\\\\\\\\\\\\\\/HYs4TuFxHlVyyEvcpxgK7Iux5HqoVGgxOuQqAI32opM\\\\\\\\\\\\\\\/grmk+ByWgQBCjoDPhBCGIQZD5KaIBcUcPyDMIUt2OUGdoQGZeQ879e5iorc8daiJ0QAEOGuz90W91ZTzMYXGTN9Aue52PcFryxpU=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022lYKkPpYVxCm+tGXfbZofuQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00226073eec1e0f73339db3ddf00881cdbc7377b6533b5fc80c13ab3e83017f8ac23\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1177.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A1177.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1070\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1070\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1070\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}