{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022IkCUDPrz3wj6qUXwy+Ft\\\\\\\\\\\\\\\/nw+Py6p6o0c09sMiWXRgmWzEO0TFBRy9iZrqGttKiD3gRGs+mhktgOx\\\\\\\\\\\\\\\/kXUwbGywVvxiwr23UtlneeZVpq5rnj0MuJkEJ++zpfE3u2wvuXnxa2BD0wl78kCTUBu088OSGWPVQdnC8A0zC6DPhHIu7DoJ8kq\\\\\\\\\\\\\\\/QqugTGf0xDyZo46f3+t\\\\\\\\\\\\\\\/aXk3WjDy8pjv0ZDPFTSGxWK1O9aeNGIgODSC7LXjJWuvJt9KhiuuYxbaRAilIsKYCP\\\\\\\\\\\\\\\/N8P7arOe9vcmknEmsn6H4k8lwKJt\\\\\\\\\\\\\\\/SX6BLfQaRTCKrFOlIHo7wryrITTps\\\\\\\\\\\\\\\/SV+ScmezU3LxoE8INxlIWHj1njnEft+7gqMd4l2cEmuDxtar6mIF3CSVhqdLBPvfueQZzKfhIm3MzLSmvt1E9aIp7nxBUi+eyHcLzkSIS9HsFpk9weBbFHY0P4GjokCuYO6stboBU\\\\\\\\\\\\\\\/HrjtM1a2ReCx0Xw8dbN+xb2vsLh4SmQS7a3ppcuRXAG\\\\\\\\\\\\\\\/zAczO7jyAq95C84LliHCjMlCI2S4D\\\\\\\\\\\\\\\/eoKQ6FbFNb9gP0Rit4ETNhP0xRvNFwPghXifIRM3dB63FeelcqOcRRLglfe3Kv6L0hC1lsPfn0AjDiWCXQK\\\\\\\\\\\\\\\/3JB6axsVbyCfz47trSb+a\\\\\\\\\\\\\\\/tuGZmYyv9iTl1ic0Vs3yQefvaNNp+RizgCukI4E5iW\\\\\\\\\\\\\\\/aYp2ERqd10WVKdtpd\\\\\\\\\\\\\\\/CTq3SKxBQVvkiyFBfn8d259a0k8Ek2hWLCblS5zlnAfheRtMZPEHLnhrN1\\\\\\\\\\\\\\\/jUYnxpHUwvbvifD1tuzTTfn67YbK5Fikkut9bHajlKlBptaUNY0Z7hL4DiiLi5TZK2IvCy0BdjFTFQxNj\\\\\\\\\\\\\\\/Gc1uKzSgDiEeDk07SjWT+Nud4mdEBqT9mNUUeZ3wDFDr\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/Q2+gj6a\\\\\\\\\\\\\\\/CaJYSalnzvCHLDlc7rWRls0FBMTOHSHX7VWgnWeAUieCPF44ayuzbdSFD2zra7gVhmyW2PgVLNygLm7qlvccepRzL1TC\\\\\\\\\\\\\\\/LvSm5qpWpQH9a0zyxMZR5Bcnv5UoJX9sSNe168PJaHGcQpKwEfvgkQykrkYI58c4XL9UjQBq9vYfFuwG2d9W8WrW4DBmofPBNewYrJsKJRLOa1mFSzh8RdcvKK1yMUkQ2O704eRrITojf6+Hf4WmATRd\\\\\\\\\\\\\\\/h9x6JguX4yTyls1wuV0CkEsOEwFQAGxkhJtVXovUuUnxY0S6J6J2KeKKvP3WtytiQnOeRu1a1ny+lvc6I3BZPXfBKVA8b9au1M4grpc+bVNl65cVmhw25V95u0hMnmAD9OszSP+J1k0vy5V0i4WwYVaTOko685YUG4N9xrxbj\\\\\\\\\\\\\\\/sShyQZz2L8NDW+r7Qz6CFjcewYwYJZhiQcrANaTUezB4+yaR9wXqvr9HuoUKnxX29GShsxeO6QPK3ol3bFzNeyoPMAsPb0qccdPXkU64FxkYpFPYWLs7vgZp4Z02TGcGphxUP3tcq0TuUENBHXZoG3dj9FFsEJQBuD1jvRL2xpH8Gv7mC5cYtb4ETzuEJUiAdFRnC9OCQ04tZc\\\\\\\\\\\\\\\/OVZaLooQxp+gmkgCAIyFZrE+XReBuWKhhwGVfUlcvtj\\\\\\\\\\\\\\\/zC2srvAGNonwfXbYWcOzc69iHm7QCKP0HS\\\\\\\\\\\\\\\/ijKc0zOVxr6MB7y1zcoK74B3Kru1LvFYSpyHeVOhWIKfersF4BFyJV23bSNNlLb\\\\\\\\\\\\\\\/DyVQGXeYrduI73i8dVT1s6aNlWtBL+QC7Z47SjTBjkn4TJCAOC8cjBy9rhIMe2vRa3N0tnPj8rtK0nn8xi1nus89TDa6GvT80sic2C88YiBglenu31HVP+IvQHFTiN80+837NHGK\\\\\\\\\\\\\\\/M93pCv3AQlc3pz7bXD0X\\\\\\\\\\\\\\\/f7fCLlORADjxH45WEjGDE7Mu38cT32qERJQqxu+x0voQQSFcZ3uWq69lcZuFhvvG1e3VLqvuUBdrKzyLTxeAY0P4Z7lYpCniSeWiBWuJIsw8c4\\\\\\\\\\\\\\\/e8Gkf1yQhJMvbtTzM\\\\\\\\\\\\\\\/ZrDa00Tu3\\\\\\\\\\\\\\\/4oR72npOXgRPY+e+80HJCXf+VLdg4jTMZz8Y6qwxdwO5gD5Hue3QXq1\\\\\\\\\\\\\\\/M5sxj44aJZNVjFlU7bhEaohb9Mo79mTljcRxHU7Z9cfoNGhUQP2bzANL1cy30wO5HxxsyV2UnX2EBibNgk2MrHtTWxVrLr5s+KmzSu6mfVTf0lrs6gUIrKjjsYNU3bJLx47wFc+oP4A3VVfm8XUP+ZypeElbr6nFZRNZN6mBfdKQC1Tw\\\\\\\\\\\\\\\/+cmSHFEOTAr9Uwo4o5pulxKqfgENpvSmGfmkCaIccR+YadWYwdECpD6kqu8jGsNOca0G3Nui\\\\\\\\\\\\\\\/d\\\\\\\\\\\\\\\/Ckw6dz2qeGlO6w0V3cisbGc0Kt2R1cCJX5m82+TRvSJBXl\\\\\\\\\\\\\\\/Tw4kmpOghGrKMHdYZ7T1paP9Tj2NmT3BNhq0K0Uc6w0iHsjh9ard9YpHxfclv9rp1UdEc8QxxVKBqjb6tNUE\\\\\\\\\\\\\\\/FZVIhjLjg3AdZNfeu\\\\\\\\\\\\\\\/9WWif08YGcloHuoDsFxZlqr+ItrzFTrU6qfMTg5OfwC3BNpBBcD85q6G5k\\\\\\\\\\\\\\\/vAIknnIbIquEMLvlFYG80WXB8mcH6hxO1q+lf+pB5iGAoJTSaEoy8fpKJ\\\\\\\\\\\\\\\/Ou511EsG+SDi4bCfw5QhaopYqB7ZbnrhwGR9f8TQDE\\\\\\\\\\\\\\\/5G\\\\\\\\\\\\\\\/wrszS91CN2HYF4MbWM8P0c=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022aaK8YiR\\\\\\\\\\\\\\\/uu17iqUDcrURCQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022d201743258c974b3c36e3342988e0a4b85fa49e44c9c8bc400eaaf1be63d4139\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A286.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/A286.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0247\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0247\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0247\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}