{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022D\\\\\\\\\\\\\\\/5Cf59nEymXOson9r8riV49zgM1b5Mtn3x64N7zBDUco8\\\\\\\\\\\\\\\/gR2wUqI0YxQK1Wvv8ZSKdhrYvOEcCjyBiH+h2HlylkAUkHAgYwkn7Xf\\\\\\\\\\\\\\\/1ia\\\\\\\\\\\\\\\/0ygeJ0k2Al+3Rusq96Xm6jsrTku++GLy02ag9VcVqbyjwsbYNwu49+ecTxFw4qBofHgHBBADhwSduFvWC48T36Wsy+PQA+1XYZq0eVgF3FzAwDtgRwrcs3r9MuOYrk\\\\\\\\\\\\\\\/oNZq8yv8RVRCPiEA1Uc+MbokFlZu\\\\\\\\\\\\\\\/qiJlE8BjaZ4zt2ji9Mq\\\\\\\\\\\\\\\/Lygun6G6\\\\\\\\\\\\\\\/SOXVmrRJPsRWpp5c8+mudWX7j9ATWCVXPUabRmU0mNZq0PdJ4i55PHGnK9dYiRcC87x\\\\\\\\\\\\\\\/sfgEOWe+ZE8+m+RFz6U53OiWrIgX0\\\\\\\\\\\\\\\/NVr6fiYnwZ9RASUq1a8tcVv+A25C1YONFrfw8xQ6F9eJQwyqriHoTBYBHGyYE5qO+1G72SPNzvHrFMAF817xSPeS5u+MzaXayLH\\\\\\\\\\\\\\\/+T+H4wnjQjjJD46lgPZNyDgrImdxyAwkTd4VH3EoOO+eeelHBfROfVDNYZnXdJWE5rceHOg9VidXO1klXk0OqNkAWBSErEfZDpNgmT7gEdVOvNDGHd\\\\\\\\\\\\\\\/UqWqorju5xN7W6LaKI+\\\\\\\\\\\\\\\/v7V63mZLWYFWoA04vueQ1KoMiBU5JyuqzdSOiinLsWJzRX98FIXtuL59mMlrZQ9yWGut1Eyfdaz9cGve1MuxZ3pJoypCQDJwbwDPUoyXFdD0B4PLvbzcRq+sEkfQOfAYoto3\\\\\\\\\\\\\\\/tFQP12UJaq3EEz+3VTR5whQdWgCzXWvciYMX1xPJkkHgDsMO7263ma0H9u8A1v63GjrkDzClXsy7kWgu5pYymc5rKz092uX0OCWY8JIbWIpHOvm1cfF38MuWDe+U6wLH90BpL8AtI1xdQkvyGbMPu0byA05D2kkSNx3mmk01wEKCgYRnnxFZVVfQtdj8TXyc9F18KL7U7bkjHSb03xxW5qu0sM8dJjPgkrTlfDEbD7ivuzxtVOJDvmrCtqRvvwjjRrQh0mtQf6q5gRI44qj0VoK7nm1ms8QzZroAzcY9j1adYq7XXfHY\\\\\\\\\\\\\\\/ukcDkV5Jp3qos6zqF3DNde2y8F5mV51NIKCNcnDg5woaFr4PrMTLpfMjf4M+wZy+RaIny6LWuBOvD85Rob61YpmLjonIxgt+PgWf2aJf3c3hhG2FXc\\\\\\\\\\\\\\\/n9xRz0eeiniR45B4SD11fqztb0NDNDvivNEseMNWQEBXlor6MM3+qAbCa\\\\\\\\\\\\\\\/uzOoBl2jduMReoTCDRUHaS7HjjyDm+BrylcmcpyMyZ1\\\\\\\\\\\\\\\/0zQJY6FH5U09d2RyylUXu9Ux4Ww5JlKo\\\\\\\\\\\\\\\/qpA97pbcGbYDNckK7eO6v88SRisU7B5B6946fDNwaFTIHzUJyrJUYDbhJdsELcHJ1EfqkEafh1YkizSckyzBSbEP2rt\\\\\\\\\\\\\\\/Aui1UUJ8550u6ISBh8s9uNVpkS637BnJskv47FnzclMGHqT3eLwpeMGLoLYAfX1hwR85Ft+3m115BQFpYy2rU75DGfGE9OHQRh7EM8z\\\\\\\\\\\\\\\/0z\\\\\\\\\\\\\\\/BRwpW9dCJcpZ3jubwbCpgSWR7iNHKHvUhza9lfnQyUJMTmkOsnGDxCB1v\\\\\\\\\\\\\\\/ldKmwQnhRlSN5c4aia5ALSQRyZ+275rPKrkXRXFjbMFUn0fGz4SpuLjCeKSfpMCumQ7BY+NW60Og1aw\\\\\\\\\\\\\\\/OH0Ljt3DPQpMMXDi28WbK2vixZ3qgGHL5hxA5TlvN1A9fVSPvalJfsn7AtEVr1pVV+acw+vq\\\\\\\\\\\\\\\/CZeeeMOAcqWIxLXuq6z9mBz2x9Zp2mAqdEwU6jfMYMVUUDZXuu8fFZi8C\\\\\\\\\\\\\\\/AH31Xi0oE+Cbt7qf8ZDlSZrf0BtzfKkZHpf+Ag6K83sq44PaxebUGl9pi2nkeid6Bm9jf+PcZecEjNY1eJuTsYcY1cC4z8GsKbDg7MT8ILeqQWI+l3SXRxQEBVqSjiWgz\\\\\\\\\\\\\\\/rntGYl+W2RzYU+vJMNGWEcyyCLwvhilEHad2WwxUw7lhoXZnEeqUsv9Cw6ip0Fw6N26eFOY9ekmN1FFFWs5rkyXLsVb21VFT1kb4BdGE3wefTyXVZasfw2uTIyheO7kxz7VtZcK7LH04GGQz1f9J0qz1s3PJHvORZVA1RusfTGi7GThH\\\\\\\\\\\\\\\/iId8t6hj9yI6IKp1Nm1qx8zSeze09\\\\\\\\\\\\\\\/EGJ55FoKJ9uqLIO+KyJaa\\\\\\\\\\\\\\\/WJYv7bRc9zFfgBMZmV5JmiJ91wMjNdvHhcffj4sXFPTl2FdrFyE8quv6QzStV\\\\\\\\\\\\\\\/NZmPPEvs1BlSNGO2paQqeeRUJHbt\\\\\\\\\\\\\\\/CwLsVvcHRWmJd\\\\\\\\\\\\\\\/UTK5gW3v1j4HnAZ7wmkk+Rx+xXBm5QLSLVWD0LLI1Po7l1MIHnouuT5w3aKpwC\\\\\\\\\\\\\\\/+6bIZN4CUDBfAbCmNk5S4adYMGdu6UyyR38wEFzSbsGa8SGKWfmd7FSp3BCRm7CZ+XpNuJfNz8TiOzLzwjRe7cpzaSQB4OA8z2pCXiTypJQrRFsWe+6fUIUNfTGVzXf9JSZJXbZp9VriliSHSXTFcWHAyCX764D2+oI35N0RCcSwcO8HQw89\\\\\\\\\\\\\\\/yZzlQV6MtTOfTegR5MYP53\\\\\\\\\\\\\\\/uBg\\\\\\\\\\\\\\\/BT6+GeA6zp20lyMBAYkmp6pnC6VrQg3WwWiGHtmysl5BkFFVD6jULbiGG6pa8qf6V4A21Ni0PxEDy0brHqQ=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022e4IlwwvuMBmUhHy\\\\\\\\\\\\\\\/pk7VPA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002281e98cc7b8dd6e538af7a08d1f7788505d57572931568f1e0a7ec23d2cc87008\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_2\\\/A1784.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_2\\\/A1784.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0222-N\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0222-N\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0222-N\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}