{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u00222cyRzT1Vsv9DpsgUSzRtStzY9qGOmQBa2ZASPYGUKsrnqvXH+pKQa1A\\\\\\\\\\\\\\\/dWr07WvDCnLu7iSQQoj5efu3Mkh849d9\\\\\\\\\\\\\\\/pmEW0bjDrWVONfjG6kcoSdD+TihClGYzwSEmhUvfgXl6a10n6+BP5mfD\\\\\\\\\\\\\\\/p63402BzaeUCA87Wwr\\\\\\\\\\\\\\\/1XtvWqdcyVg6q2W+GEXkDx4vS1o8X1X9DEqfiHOviyzaYIPKrDKkBkL3Qsy1JnSCsOvyQAPEa05KGQ45MM5vzxeNLCWnpKakJuQV5UWFihSzeIb5T93zrPwk7UIAD7ta0TJ4LCwGo6FzS170ftLcdN3QsW0gcXAVF9W\\\\\\\\\\\\\\\/fMLOZ0C8FsIzP1TX+o4GSOPZ0T+RsiBrb5BBWBTx+b8kvjyNx7K14\\\\\\\\\\\\\\\/TVQaT0Bs9nNO5UJP3b50p\\\\\\\\\\\\\\\/tp8GlgF2VPoR+o9gwTtl+9ex3lHHSSvn5BzxeIi2V1IwrIzs3YZtIldoHGtMGd2xidbcdqfEd5jWoAAovlK2cUN9GDRU4YK4Rnmvm45pkueiqVWSzctbsr2oSIa+WpvkKGKlOSEbuCu1lG8DX5pOaDwv3wt17WdIWlmdwYej2XXFhFx+UQN\\\\\\\\\\\\\\\/ZsuitoSoDYsUhIz+o8pNXDF\\\\\\\\\\\\\\\/bTq2i3BgEqnmkUaeDQRWEGq8uHBIg0vHlTddm3K4sUPUEMEqwTepCMLPFVzTaJ2M4VB03eWCRPAvFXGRVhVvzmdfUdO9CpRPTLNJfw7XXBYWZQGPrKY+4uVUpxTTy9XGRKK4bIUti5bhPhZi9tPpMhS1IhaE1IAQFbF1k2GQy3np3T65ziKmCWeFb99HJ0\\\\\\\\\\\\\\\/I9lSIlm1\\\\\\\\\\\\\\\/6mU9LeVNISU39tKSO6evbCWP6DHRwJRpFuXw0ejLxmZniwAW1PKfQuUs2FgboAXopn5YXpIY6Y\\\\\\\\\\\\\\\/9I1ek8BN+oAzF\\\\\\\\\\\\\\\/oX+ZGGnsDkZWSVibuhAxjIx9Ky7boerFOu0mSV4RirECxu9IsqWKhTM3\\\\\\\\\\\\\\\/s+tVIXaJNaPR0bj9jtb\\\\\\\\\\\\\\\/OvAh9DKWE5IwKo13OLOsNYQGHhqTjPj2sXIbZisdtDUh703IUY+PSEmQJUcA9yuPucjW00eDfProXHEsSWoQ\\\\\\\\\\\\\\\/Ch11WOL+x0mGS3GLcqHFocraVI8oFvV\\\\\\\\\\\\\\\/6l0KSr4WNl9UIN20owcE0g0dfyONakk3sYxBodY1ktTC5f9sMgoNEFo67uJWI0GXPYaQNU5xn2N9gUzL0sxmYUtWdW72O4kyr4oRXU+ZTDF3PCHIj0QLMDOgoUQBbbuNLYLbDqJp+6HFjScb6nfLzjLdRgGYLhVCyuxNmu57zLlyGBs02aYE2Ws7soq5oiqBnogLOY82A+5tOjEwOQXcehHyYtk3A5f4IhX3zkiJ4AvHVMU2zwp+gGTlVnVFPdlc3DwrvthDqA7XDLdZZjEqmywatktBMKBh8+TDgb6bY75iTq7t595gpln\\\\\\\\\\\\\\\/KEoM\\\\\\\\\\\\\\\/bAuH1\\\\\\\\\\\\\\\/M8clKZHTeZ61hMY9p3qsLmuLnro2ufci46gjaS\\\\\\\\\\\\\\\/1oBvQN6rUUTdqWChX850i\\\\\\\\\\\\\\\/yxACl0EVkrtLIuBCzQQ0LbjUd9PjQDbTALAwth4\\\\\\\\\\\\\\\/EU7JbMHTV7UzTnlRbWF7o5cA\\\\\\\\\\\\\\\/v6yGDzVQELn2vvXT5aRYyAoA6SwQTvOmwuEuECPZa9R0fngbYqeiwj6tzl5EZtpnKrJiMPzCtnCtK1SIHl\\\\\\\\\\\\\\\/SU5W9alzNHtFRxYbRcMFXdOoI5mzfBSbWwDABb5Q1zqonkrsI7zM2+RDdT4GALpCzjiUEWQIg3g679q8IY1xwKEbPv13+zKdtNRSYMH4m+ezmMFQ6yMIDFjQAiZz3QREOzxM26nWLIW4s3Qe61dbSf+5R4WS5Z3Ea9Jf0N1VYLSXR6k7NR6J0SDDmc738xmkBvX++k3TdMTukjOBznSR9OKOyzQHo+BAyeyqy\\\\\\\\\\\\\\\/e1\\\\\\\\\\\\\\\/tneKmNz7Pb3RbzmSVEo2q6gVOfxOKK\\\\\\\\\\\\\\\/ZkeAn7M4JEr0Ti7QJ293BTCGmjNKp5nr\\\\\\\\\\\\\\\/6P7IE9x76Kf\\\\\\\\\\\\\\\/DZX4zpu5e7fV10EREyzzPSF2ozRxjSA0ZdvYK5nE8Ub6cnupiwW4\\\\\\\\\\\\\\\/CNMZx3dV9zMiaP2KTTWxZqBTChzAo43kAC\\\\\\\\\\\\\\\/Hjc+TqoV4RlsLfMCyzkjLO29cEvHkzbKCtivst2iD0wvVfarnb9B4rQvP+vRvzwrhejZBSaG71xS6EPEcn9fAXZPR8zNq8ACvAeViUEYOJj4HX6ifC+RQgb9s3j+Ru0qDhwh7aiulV5gdvPfV89qyCw7UkMzXVLXyJNQAL4kDf2gVeXrvL2iU0j8fLKkgBwirvfiXm9jxskCOBhv\\\\\\\\\\\\\\\/TN72rzgnhy\\\\\\\\\\\\\\\/5uHQ54kVsfSszF7hy5pueAdYUA8+udpecBd8BU2P4mVArx27oal56JdEa0oCMSXaxAM53Cp4PevAbAz7DJ85zABRKutPuR0uYxKTaJhycFnt6vPE45YUS+YnzK6oGsFtkuS5apVkw6qPtOcltsG3dJKE5ZHMPdO0rBz6DDeZ5zlr+Xgfor2paQPeHaWfWzP62TTq616YlJY6eJt8kurlwrmDeUQo4nRFV5R1TfqBUo7aszxiBUVlJw23HbTbTGeSl\\\\\\\\\\\\\\\/r6aR0eoYkREh4H0CFYG+5xy8yffxwcF6jDlKR8avdq71Wtp+uRBjbs771SZaBQFFofkGfkZ0LlTRoZcqzCLR2KfJiBnHrKso4Kbuy7mM=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022zHYgtyvXMu0jzvFX6MF9eg==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002223ab444b163cfeefaf59a0006f765c6e346f6e1537b54fae9bf5837f9f80cd61\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_2\\\/A1786.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_2\\\/A1786.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0442-B\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0442-B\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0442-B\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}