{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022pSL6u+\\\\\\\\\\\\\\\/nVs1HLRbhON5yvxasxm3hx1DlX7v3eFRvlvKNiJBSXru9c3CKkC6xUUIHjpj6D24jM5JJrpyehUBdEBOOXDTL3wlyPZNyhXUkU9NzZnaC2fq7\\\\\\\\\\\\\\\/LtjUktNYa\\\\\\\\\\\\\\\/UCrm38cNewHtn7U+ANqYjEVzJnokVUNANQkI7sp+E+ua8Xzr3RBDlYV2kUePOmy\\\\\\\\\\\\\\\/cU+2tjN8VdiFh87WfOVfp1j\\\\\\\\\\\\\\\/FKsOf+eXFVXHURsWwzh2r6foJ\\\\\\\\\\\\\\\/jxtBFgSMBUBXkw9XdoNhmSLv3eELiggMHnzkm0EJbc1NDmRGphXfvXVNsj59U0Z5GYQtJmB5RpKiMe1r8bUE38QHAINUlY6yIA3hDgZibLpM0u6zYmtnZVGANZk\\\\\\\\\\\\\\\/JKfjyxN+JQPAS9aosP3dIofb09aSggQivdZbPXNPOJYOxRHWKJz4\\\\\\\\\\\\\\\/1q7QQg132ZtdTcLmWGRXYG6QPpD\\\\\\\\\\\\\\\/gmvjlU6v+\\\\\\\\\\\\\\\/1MNVE6eHuRBRrjk6t\\\\\\\\\\\\\\\/32YEmBWU1TUZvMGq6ancfqeyGzG8f460TvqTE+m7V92iCSY+Yet6PiXJRyrXI\\\\\\\\\\\\\\\/8qWEmMiQtH2ALJYWh1ur9JylagDgruRMe0zY1yotzn\\\\\\\\\\\\\\\/9ZNGygd0bEGfmFGmCVei3\\\\\\\\\\\\\\\/wRMGc6PRUKJ0fwgWoHyjz89g0coaMfLTh8qqD0H9WIkgfMADWa2HcWXb7L0naNxH7jck92MajSsaF+K85u393tZRkqHLILmTNKMheLysUji1qDrrTF84tAtnhGE3pUCnL\\\\\\\\\\\\\\\/Fq0sj6j5HQqJcoiLVHhOsHGNc0hGlYkYs5vtL6gLmxBls7+9ZB8kwbRlbiqFJrBaKJ7jV45bKMFBnDwIKio2H35R320FPVCVvTozrx219z5iet6q9Ymcim7hCUvvlhTCAobn\\\\\\\\\\\\\\\/9diRrAC8B1wfkJ7lLujQGjTaG1IkUk+FLkpRwy7JauKqS3MlJZikc0b9WxYH+YDTIGruV6q1x61NmKi7zE\\\\\\\\\\\\\\\/6gwS\\\\\\\\\\\\\\\/8p8QPBd0MvKISUMcRH8Jgxd55gttOMQRXE1ZK0xwts8\\\\\\\\\\\\\\\/4reL4gMt1tH7geSuz7KBIdfuJDtVC0IZvswcXd6CSUlAAqlukR6l+CHs0umGr24oyeRAuawr4w\\\\\\\\\\\\\\\/r3fwQTCtBFYVmf3GQ6cDmmiN+0q67vdVoUz\\\\\\\\\\\\\\\/4PwPXb9QYs7j5mWy\\\\\\\\\\\\\\\/t48rm88hdB6e567IYSrT3XE8RA3Uk58X4wna1y9ebxoM17VPNan52\\\\\\\\\\\\\\\/9LqqYyOskJRhCzERmCekIRT+ZAMlNhEkzOxEFIJfCrRW51kjnhUuEi1zZRMKVwF\\\\\\\\\\\\\\\/rFawsVziXcN+NYHWLknFLNG636bGoqtLTxxpkSToPKbn+zgqucVZBrdMTvAraB7swVziPEtBb1pUIOo3SdWI4VrLuhuBeV\\\\\\\\\\\\\\\/qI2Jv5NEPdiWPRWN4pxJVp2N\\\\\\\\\\\\\\\/JLOhcTLQZ64w0JmCf6\\\\\\\\\\\\\\\/SW43KWeeMCn+Q2LD+0Ryk+FuPk42AkZoy0Q0iT08W+GBGvcDUhZ\\\\\\\\\\\\\\\/TU5HJ8ptF9JYTDcY3qyuedYvedS7HNL33KSr6O5C5QNJUZORFkMG92YRBZs3J4rjujLmPDaEjT+Cz12Tq8NtmG7BTBhcnuDf6fMFRnm6ZmKwLCuuHvY9JCyOsl0JlO16uYO0xQs1O6dW9wcbyMqtRGZkNQn6yl+l9JcNJTldV968m+wh3cc9Rqm2pTn4bH5vNnPXvGzB+ZOc4SsWHdJeHRSD8mta\\\\\\\\\\\\\\\/AqU9OrK2thmbCQgD0ppCoV4NXcEt2AJfnKKE+L3r9eau4PYAI05OrGqJgJ1NPPeVN5RkNBIYgrvzRrKgk5W2GCUARqc1FMVptdyQ1CcKM1Dsp\\\\\\\\\\\\\\\/PnASXMmHA2+EZfAUMLDIHFVjsTJUzJsynYMULQRNzBmnxHqKWeosWmWAoUKncozfQ86yaXkBLj+2YP6oeXbAXkpjHAeFNFeYjyQVUYcoKw6WP\\\\\\\\\\\\\\\/sTb4xUaBAT0V7hOirRZsjARaDbzHIYk5v7dj1911MgUCRTimETwvqkqFLsGS34rAeeROnGswgyb03L6IOS+2fMB3vA+4OGzaCxYoWBrbVtrqyDk+CW4wBRvAOkr5IptIdHDr3IRY\\\\\\\\\\\\\\\/jBOx\\\\\\\\\\\\\\\/K0PukafCYhgQI18hr9zRlpvRioiezF3+G2QRVO+nLzYsWMQqrFr47H8f8mPtKITIxNX61K8iTI64z0w5JLIAmxuZFSPlMGu7zu86QmIHjpe4eHkO0pKYLvDuwsSQ63U\\\\\\\\\\\\\\\/yPSl+n23kbez\\\\\\\\\\\\\\\/SRsqYIMPhM+3MaVPqpPwBWimK19ScZ4t\\\\\\\\\\\\\\\/WxL\\\\\\\\\\\\\\\/hOyp6wqin47PCHnHs1mVCn\\\\\\\\\\\\\\\/0enHx1Cf142UgyAglBr45BCTwWQ3Wz59HJB9KLxLet11cFrjqfL\\\\\\\\\\\\\\\/b9TK8kKyf6trdUWKXxltcD3WhKdJzbjcI4NP5g5IFIApOgv+BDeYgn6KQgKdiIl0qw+eoKthXtoNf754nGchv02FKu53XWKqY\\\\\\\\\\\\\\\/c\\\\\\\\\\\\\\\/ZKnpfoOKeBqguULh3ZOfT8lQ3rAhXbVbJZ3VaRdlHrr8BYoLc4TYIIhwSE5TIpnhG9IzjehtWxDegeJNayW87E+wI\\\\\\\\\\\\\\\/1fB2Mz+N1fR7Nm6e84JW3I85dlQyjvBS8rNomhflTZxtBG9pFhdbDbEWuW7niBlIqk9XKcOOZ9TsjEVpnAn4VCsB\\\\\\\\\\\\\\\/rA0h0xZc+98UqaDXC5rObFoOty\\\\\\\\\\\\\\\/pnqdThZC5OBlQFgtxsthqf1\\\\\\\\\\\\\\\/Gup8=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022gMEGi7cvtwubphSrwVSHKw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00229cea2eac1574eb3cdbe8c333068fc0bbedde522af066126cfb6e918367675012\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_2\\\/A1770.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_2\\\/A1770.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0222-D\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0222-D\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0222-D\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}