{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022A1G4eUx+q1BiHaDUpweX9Mfl9yXHs7FERzGtAlOZVsNTu\\\\\\\\\\\\\\\/uLyI7mDfMZKjvFUbb5gwckwGU8GiBJKblDAW\\\\\\\\\\\\\\\/QqX8id8HBzjv+mmtHzZNgyw4vZuqyfk02rVN36E1W0Clryvptyg24ba0HE9p1zOM2EWQFujY+1W1n7RpezniwjSiFUyz5tWoVN1mx7yaPKLwYCFW0N39mp0ZfzFf2DsJQPJx0QtkbFe9uTibyQhpdsnMMnlYLHlI5n\\\\\\\\\\\\\\\/h8DneoY7DVMaDehsUnW1wGSvUkDeY0wO9zjd47YIywRIidp++oTyd4UdX6uzX2+qI9bgNaamy19KGebeARrSJTGryua1xHZypjoC69S\\\\\\\\\\\\\\\/ugsTZzZqlKmix1NKTeNBWEuuHfsZaFnJ27mwE15S56rE5wcH\\\\\\\\\\\\\\\/j2eKasW0nNmtn23OWSj0N+j+U28Aae8nzxQhPKPi7EwMTmEXsy0qJ0K3KNYuZx9\\\\\\\\\\\\\\\/+zcgmsiiLn0BTN4c1vkrDxcfrDitjuQinWJWgRmRxygsGJz1o9pGURg9To7flc9pw0vrUBC\\\\\\\\\\\\\\\/zL0dVWxQ1K3JofKVICKLKyeCC7YtxZ8PiPuXK0jrTNpuuUPo81YHGUNFgLGeIA2qKzbkokZPVXHSlf5arFGzunMdpm+Z1BlfKLsrIaAuSv08NznPuafAsGUbrV5LUsL5kBmrhM47mOpEEDBeFPSkHOaimsl9TZR0NuRNU8EJ7XXGBNi7w8TPQAMXECreUqkRIrkLann1wxkEuunWtCmNrefqjwUZAKUSLm8cvf6iuupguvL9\\\\\\\\\\\\\\\/vNclf0IdCkQrDvm8djF\\\\\\\\\\\\\\\/BPercv3UXjbux1\\\\\\\\\\\\\\\/Zypd\\\\\\\\\\\\\\\/DlwN9MbqTB+WE4yiKZex32Jwn+H2Nv2tWDWmXdmc\\\\\\\\\\\\\\\/U6HtwCSRmqbF65joP1E5WBAolDnUPYq9p8ha52raXIrmN4oUD2fFVW1n4TRfHGoGxo6t9\\\\\\\\\\\\\\\/0r0jH9a\\\\\\\\\\\\\\\/9xxLBISxFaw3y49KgU8iuSEO3zqcSXjH0KqyK6SXvglBjyvtSmhsyR3IJmiHMSN22UiHzi1KSOBx7AoqUtJ6uRRn0dJyZoDFJ7FfjRUDoqVrBfCWvmWHAXw9uR86tFArXvPI5PDDCZdvrDd4p21MZyLBbTyV6poAqi0RFVM+TO9Lxg4dRbQx2cc2tV73Mlx8azI69z\\\\\\\\\\\\\\\/7jDMMiytfI0VeJuNSlkDHNHL1CcOKqhNEwNziFyvdIbNGGP51tj\\\\\\\\\\\\\\\/eO73TipmXtM0+dV4FJIBpmC6HGA5gySjTtCYrIXNRnf4oiNOMph8KSFOtKYJdv0Ik9cooDncNduYSNyDyz6EaoFiBLrqMF3nXkEiUnmc2Ptt1O1t\\\\\\\\\\\\\\\/qhz\\\\\\\\\\\\\\\/zjBM5H05Hy2KMNbpsWWUrWpGnLD\\\\\\\\\\\\\\\/vuuTjxbWLxgoOfz+rCeGjWlxMjwALY0jnLCfkM8vDJO8dsTbcEcUB38iZn2VgXYRCymwHSIwp7NbdH31SxV9bcAAjFgVd26QuXRChJt1k9zxdDK1uXR3uCrHwV5Pnm15GdCtOHcodLYCFaXuXicUAm752oW\\\\\\\\\\\\\\\/KMOWkw5ygTRxDGZ1y4fr2EtqIOPGM00GLbp4RAR2Yi\\\\\\\\\\\\\\\/eny70JdyPOzO7pEGR4hJfyX9aYzcxS9z9v+S7ekbMZ4\\\\\\\\\\\\\\\/ag8nOFApmHXI4v9JTfdemFXxzVoNQ+n2URgGvk17cH2GzrSBZrgqV1Z7SHYgxQLN9SfMfUL5mPRymhdmxOQZgSBvgJ1a2o372vYaZ2sE5ouMpKHx7AVs1nurBiaBImR7S2k+X9BrRbyb9\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/ggyTYcvMbdfwCLRs6iLhoqfk3tXFyCATPnTACFUw6OYBSMLstGhn4vmzdfnY6R3UtTczH4WFZ4JICWq9dx+1NnGygFKyw3L95Gd71ohoLsFQdjOUltfq9nR80oJo0QpfTHfdDBCy6F4MCK8pCEDtXoZ8FROBbTRFkBfzuU65Y7qXPHOZaOdnW3M4nEXlwgoApJ2pp6jj1yKTxVz4Hs6d6HJYM4x3WMaxnxh498ymw+pfgwrL7kzA9MqvdJMnL\\\\\\\\\\\\\\\/A5q4xGnwe9k5yqx8QIntnc9Q88ImpJaWoYWsLHdd25ZnPOhDclaOHz7dtC\\\\\\\\\\\\\\\/m3ZdD3nPgx63X68O54eapOUY57jrPXX7A7pKM6cHnIRhwScFjbsQrc7Y8DnSojOHWfkTCeHiYScxhn6KA0eVBuTTSAtM9p055VztGB4VO4Div5SehVLO2kaxrxwTog3+E8WL8VPJlQyoIB5yOARunJAvP2ukULJVmxjq2Pjhm3KbwmVcT+woyHD3pEQbEQcFljXW4N1Q9lVsEqNdnYHRO+xG8nNIJFU8V\\\\\\\\\\\\\\\/5ufAD8S+JWCD2lTWK0D6XqUSFR4oOgEViYI1qH5rnRe0GmWnpyNqDWkxok5y0xgs6Z3dZK7ny9foxzs0ZeJrIUR9KLaJ+++WiykEXzoej8T5mZ4gJNiMqQhHktqMhpIkxNhUni8xwnUInRI9XtM3s7LnRUqbCase3AwTFFCpbhSnWAm7CyPfvgDg4e5ouETFMdThhd95sPG+CvR\\\\\\\\\\\\\\\/Apeojxog0K3faN+g\\\\\\\\\\\\\\\/tRP3wOWJBsyWXzcHPIAH2T479BQFH\\\\\\\\\\\\\\\/2muozWpugDToY736BQ5EHx1xCYG4hmlQx1lukFInRc4LKnNxQGXwIQFERPh7c4NLKtPVN7EO2fgl43BHM57g6jos+xQs=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022WF52E2K5f4+wdXelC2KFGw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022d71243d769ed7e8a125e7eebeaa1a98bfe4d614447d4c620eecba79b48bdf3a4\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/1475.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/1475.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1324\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1324\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1324\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}