{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022qwjZ++nyA5SzkmNXsNM+gkihotpjhLe0P61+lvTmfqka2m\\\\\\\\\\\\\\\/0ESgnPEsvqNthqobYd\\\\\\\\\\\\\\\/RuqkkfPRevMlM9Pl3zUohu+1PEVMYMu0R552u7UxZF5PfhyuTaeAHL116u56lchSlLSUcuyghFN\\\\\\\\\\\\\\\/4aYk8dsWR2LMoV9wrRsY+pI+FR6awuKPCByC6MqZOs8viicdnqdHsy+OOFYYRsFbmjck2nZHrHWVT2fL\\\\\\\\\\\\\\\/e0uNJTSFusbYzFgYLTli+VVlbj7g7NOCqt0LqoVZWcDs8dRloMVf6Po7T1rziKlh6wuHfl6\\\\\\\\\\\\\\\/Bs3U\\\\\\\\\\\\\\\/HuSL4OvV85stfQw0+hibqqFr4f97E0CHSIltsL5TCK9sIfu+VvehFlUCAa\\\\\\\\\\\\\\\/S+fCDnfGilscsYEZXJF5auDV7+TMRvm\\\\\\\\\\\\\\\/cUeOU1csPb5QJ4xfDhdqEEMdL1iNamkI1GxAGjmsN1LcrYp6a00XzDcuvdlPdMK5suh16A0jz0edHErTleSF2ZVPLwXvZQsu7VmmmdwQvgooM\\\\\\\\\\\\\\\/jgzjYU9OHqwDqGCHVu8ykGkC+dTEpyMNU149ikV6d8TNTm2xg8\\\\\\\\\\\\\\\/sLk8NT40lw7CHb+yG+cxKg+Rm30X99dZkTR16lzOP\\\\\\\\\\\\\\\/Glkmz0fEx\\\\\\\\\\\\\\\/58RoIbrxtHk4lspxN2duNxUBzsv6LoKbIlDfn4NQ+ku1Ui2h3K6QartGLvOO\\\\\\\\\\\\\\\/ek82acufkPTYDBzQAxOrN+OWTiRKdQjkdA9CU27Mfdn0xRZ\\\\\\\\\\\\\\\/LeeTrZnmIWdE6\\\\\\\\\\\\\\\/8NURpPb+lv3en9uzVsFworrEuzfEmGJ1sg2Ucq6qcjLEWulDrOE97v2XhnnPBoyBVCrzFzIHeT0N6oGaxEDhDY+zi\\\\\\\\\\\\\\\/EmnnX+1uSl3THXLXcf4etGgp7Oyt9pw5eEirfziU4XnnzyvaO0ehvpRUD2Tssro4sbgULkm7RAw7tX6Pm\\\\\\\\\\\\\\\/OlN7+sk2CCjqCDEv65lRjlwSCqHXYJr2nGadLYYuPa+209FZ9Bq5Zp\\\\\\\\\\\\\\\/UA9V4I4hsBHFKvq4co+oCe6oEQl+Q8gaTivBfUBVI+pw7B0hVD0Cc4FgaL5bH6DaXZL31rBzZDszvRoO9GRSMa1qhP8bctFA8kk4t6YsgadE8TlTBXge+rcx+mDNT2H03\\\\\\\\\\\\\\\/B+CX0dA75qBYqV7z6x4FZvjOs7LSGKhQDoZwbaszDlhG5sXLOej5YQXXBrvLTMYLMFgcPQtp2RAvQqYe9NeAr2d\\\\\\\\\\\\\\\/SmBK0M3oS03+88gg9X\\\\\\\\\\\\\\\/alYRrRQVHspXhUxn9STDa2KCqbYKd\\\\\\\\\\\\\\\/+rZHwOYxor5oNuSGAUF5I5+IrALlGCfb5bkp8MdfDKorlPpUsC26CVDTHHq\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/Ns7nZa12pinLC3yduILhqSVxFVPwxmZNDv2PnC8eng30DVyB5SwJlcSpuCLoyfl5Hxeub248IMcaNE51Ig6WSMn8Vs\\\\\\\\\\\\\\\/fbl8NaXA+Ra6mOv06coHs1CUbVF+jHDkLYzaXlcupXvQ2MB3KzHvUoNigHYXedWv0LVV01DIVgaPrcTNLf5tExyRJnUGCfkWdE9kXkAZGRLYbl8e7NkhKtuO9kIqhZEO9lLjUIdmVDHadlt9wofQvXpMI38unVYkLldII07bW2eCK+MrtH3D6\\\\\\\\\\\\\\\/iaQASfEDK43Z5Qehth\\\\\\\\\\\\\\\/Snp0GJcR32by56784UNQ0Qmkmkhy4CA48g\\\\\\\\\\\\\\\/4roatVqxPLN2w+bUG+DWL88yYiv1AkvD8pAbcG7hwShqjFasF\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/i42lr9mcdNDegOW\\\\\\\\\\\\\\\/Y5yIny7IQiLyXb66qjwA0d7eU6ZDXwDALVjw11hYMSNlIoSGcmg\\\\\\\\\\\\\\\/yLwMgsG3rEGk3OU4PERHnl2MB8RMcXdK0G2+VBfXcn3nwNPItTKatVKhQdJXdh8kRURdNRoRDTXNH+DiCK2r2snJgzdhD0kRABLDgghEqhBOFhv2yab3E5j5FZv8zZPwL1ar57HDXmO6H3yhYCLb1LqDTWnWl5cl8Lpui13A+DIvP2TEkUj6kttSBkdLIUPg9lFEfrfIOpHsWUlsnkEzhsKI6JqRNh921C2gfHmKA2EysLQb6iZussooWfCkqqPB\\\\\\\\\\\\\\\/FK3QY2e328t7kkMBfdjji3+HkcTDusQ+Lwjl5Z7X5hU7F5iQbJYLfFFd3hu1K1mWE9D7ggo+jAuoe9vRpqgCFcT0cdXc190jUcECDcZPyAzd4rIl4KZCY1HMBu7KoYGhllMaQiQ7j71qsuKL\\\\\\\\\\\\\\\/yaNQuD6hbUVi8Mb3A+6BbFedPUR5GV9IMQfdIl95yZ7oGPHcr\\\\\\\\\\\\\\\/gj4EQI+27QcKHBNkpCWKMH4is9U9gPYlekB7H0e29V2F037\\\\\\\\\\\\\\\/YBJEQRJcpoTgqJSiE1LTrC0\\\\\\\\\\\\\\\/V3mSlg3n8xsE9ShlBjbXw1y+b4KFIZvm8ZA2Q4XvTNYC3sh6Xt9ZuI\\\\\\\\\\\\\\\/ZO9Uj1aO6Pkg3Iw\\\\\\\\\\\\\\\/RAjjGbiqMFkm6jy5qmlojsH7pEob4y9w+dCJyNWyFIGCgrag6emlmYRMWX8961L+WhUHFeYabxeWVirU4Cl4098vJGUukUgeEN+tcZtE8zyR8gtYkk63S7NWwFuru6PZFXhE\\\\\\\\\\\\\\\/pH6w6txk69kS4wp+RgbcHALcffqdBsKkwW73UvHFu7gbO+9WCNgCeqV81WChgUVWWPTrvH+VDCo++IbOmGx0EuWt9pXvokYiuGBwhc9XoKoW6S9kEQatxRwVHAPPQj\\\\\\\\\\\\\\\/HkhQ8Bo804AdMNk1D9Qk=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022jAumwxzHkxhPInt\\\\\\\\\\\\\\\/6r4acA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00226808aabf1ada84415172df8b0ecb3664bb91a0b5f6a05dbddae082f48ccd8756\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/475.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/475.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0425\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0425\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0425\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}