{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u00226zRJC7+wWu8Am2+9PQJH\\\\\\\\\\\\\\\/PH8lMLhuSsFMXERc\\\\\\\\\\\\\\\/gu5ojGbkyELJHsOld86s9OxJGzD4vDNAxZYatiIN\\\\\\\\\\\\\\\/kOl7kLrO\\\\\\\\\\\\\\\/xwWGwAQLvPZQAccgehRStN95Y0McwY4LrTTZPeWPTbqPrFV8cmI39OO\\\\\\\\\\\\\\\/hpAje+G2ULQFnJVkzMKKH9hsHcWB7vvmLzsTeC3\\\\\\\\\\\\\\\/VrR8DCfdyfCXSx5j30fLxd0RnVTTOfqw1wZ9n\\\\\\\\\\\\\\\/Dcg38QXZIIjkMVxUA4JECRjFmy3ud\\\\\\\\\\\\\\\/KulfSgHZsKNj95Di45Yj8jUvkBDDAsaX7CbTu+jSTcPS\\\\\\\\\\\\\\\/CHguJgxoHLW5s2\\\\\\\\\\\\\\\/VWMDLqzih9O61FejlbJ8iQtgFjy2OmS0KUDpZ1fdRLSj8w9mPJbJje694\\\\\\\\\\\\\\\/+7rtAB6rvVf5NV2Q39iHMRsL5vGhmqyfQ9+\\\\\\\\\\\\\\\/v9tRrLgTBfj5\\\\\\\\\\\\\\\/ZAB0WEKeJ0TN4dY6my+3YwKN035baWDd7vs7ZTF+9ROICCx5T0aiewgYfdvHFcdqPEuMIsVabowuzD11liSwT9IBaLae2ZoF8MuVqleFET69CCNr3mh0cMF0gUkHZFTOIJbt66y2efudWhbNO5BO5fnaw3wQBse24I0mJDNfcytDrPibmzkHiRifaFwOr4eN2B8Ja5rPBjiOS1zCGNiBQLMbQH9lprfiS3sODNfhm4h06MAWerbZjjvNhW1ZLPzGmLW1YYxVyrjPixjYHdb8GYYjiHbu81p5sbW\\\\\\\\\\\\\\\/ZIk+c+FVfigvY0YlDOF062zvp4XJu94c9v\\\\\\\\\\\\\\\/SNONXsqzvaE6eewOYIwj4OMBWgs8Kap+WoQ\\\\\\\\\\\\\\\/BiCNqbuNq6j6AKdVPWhiOSp8JOFGJmIt5osMjKLRCmVAVbQQpaW68VrJI7Ok6vZO2XKRlaNfZ5QkCqW8OKIp\\\\\\\\\\\\\\\/T8KHwxbTI6+JCLrOZoaU7F7mSpXXcaIGWYeJRSsXTALVUx\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/rAGlqmMm1Eov5Lf4sgjpI+mpPrLF3sh\\\\\\\\\\\\\\\/xzkPQDNmqyN2+w7SzExK+mGMtpVjve9L9g70dCjg\\\\\\\\\\\\\\\/dPcwD8T3pZyV9Hmg8viepWTNOSGWLSu445jRC\\\\\\\\\\\\\\\/S4BLzVW2pFL8K9aWL7desBbjLySVcLKFW4fsPMoc4j\\\\\\\\\\\\\\\/JAT46uyGwQR+yt+Uyo5eOBL3O3HfJ8hYV49dWQss7rFs9Vi8t1qV4f9p5FXb0fBc4u7qVkQbYXw5P\\\\\\\\\\\\\\\/vWSpfKnDFlYr3QVpyK2Dmr9LASInCrzW2O\\\\\\\\\\\\\\\/1KFGYzci9d8tgHOpVjWfcimfi2nhdYw7KS0roWxnrnlBmf0WMyscwk4FZgeMfGraoXGibvnAY3r7w2EKDhNlEXyRE\\\\\\\\\\\\\\\/vnhfUbprpJRAZ2sQ609eMU5B6g1KDvbZHtS\\\\\\\\\\\\\\\/NFd3b6dpXJ9VOVUD\\\\\\\\\\\\\\\/xu9fVNJ6cky4DJhiMgoW2ftF5OTOb+3HSBYJ3PheuPTcK\\\\\\\\\\\\\\\/twwpmUmouapabL5QI6DtsZ+lmHzd4y2hvlpj9TFIlJWmn9HX9FNafx4gHB7OaRN2iN740XnyL+ThL4hKRp2gm1d+ws805OZVm77aOQtnWctt6RfEvC6bcQxlJlYSSSH6PVS\\\\\\\\\\\\\\\/dpQ9M32sgtz9fmW0z58tQ9BEXFysaSrmeFivShQAcfMN1moshqqYNKuX5DqDC9yPTsnZxxzKmLiKmS\\\\\\\\\\\\\\\/arD45zLqPlV8nH6jmxH4tqn6f94IWSASdmstjmYKjWx3sJJevoNEn51rMp2QwqSVr74UriycIMxgRSURw9JNRdSvMr6203v555cWCi7J+IBa9pkKveQyLqB3coLHsVJgrKtoH\\\\\\\\\\\\\\\/wlkgi\\\\\\\\\\\\\\\/gUYAJXh5ku2OSPogE1500xhncsEu21ENqTsg1py8uL7H9UxCRAJzxq6DQTmwwwYVXBcxrGgYdwml6ynCYwWldmMK0o7ExZa3kCnJ9q04sxhpTAL7lZ8\\\\\\\\\\\\\\\/GZ7pkNTK4LDJbcas0L7cy\\\\\\\\\\\\\\\/+EuHEZU4MLKX31o6wmGGKu6Gnn7YhPWNhp77JRaT95GsdOhBSsu5ymXsxQXT6NyhA5FVoKuMFVPtpx8k7R9+Ye9jAhvqqKL7fVdKT1uCklHrGboWQ3pwXxXvtgIJS+8ODjitRYsI5DYJEONN8JXEm7weWqNrps0Cev0vsiBOWI4vbHB6BTznSbKBYJ4+mFbo7mv9OzzeESmMHilzcdDaXcMrkYktnoIMWNzHd8UUUjHRxqsumVoctyZ620nN3KH4xdOcRDmq4I0SkmdIvT5GFNYoRGpUChGx0YhZSlDRjmnhld5IBpFWgWX6MiwGK2DS7zUxoA7tqvdBQoprcJdNmM\\\\\\\\\\\\\\\/RPX0ov\\\\\\\\\\\\\\\/TUkqPcNhvBc8OEYZSTpLm+4J253cpafFXdTx7LXIOg9scqxE4tCzp3M2u+eOfHxeDf2IWXgbXRfwbBRt3G4Fwx7ewxjCO2kJ0Ee4VeJ8PHffylINl+ESyOv1Z9qzeG\\\\\\\\\\\\\\\/98p5vek6pn0m8pp8D9uicI8gDlFc8TjMyIcZTxRjyaO\\\\\\\\\\\\\\\/YlGdxntMyBVIrzkhnND8Go2g42ukosTXkPTwz1YVuWuO3MH47WWiE++gDNjyXDNQRbuKmIBpCwQnNXX37MZjP5brYf8UhW\\\\\\\\\\\\\\\/dmhq0CdHwzAhTm+bTSRoxsaWl05PzRoNbnPyj\\\\\\\\\\\\\\\/aLHI649+EzjVwERofBILIhVi7D0KKnvIhCILR9+1DMy4LnqUzrAQB4yiw+6OR84X0KMl0x3HJvjZXFkNvBCYsIdwI=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022NNhS3G7Y3Mt\\\\\\\\\\\\\\\/1qdYPcKB\\\\\\\\\\\\\\\/w==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002288525d0ba1bd4f38dae0fd26fa116ca1603286159f978ccb4dfcca127c063ecc\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/1353.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/1353.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1226\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.1226\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.1226\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}