{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u00223caywtitgTBZJwfzpttRO+GYDxmK2fkkQCTg3jcaCTJ4FQU19rgz8sYNoTxMKJaQuCkapyd6H6iOTWmZ9myrvtZOrjm\\\\\\\\\\\\\\\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\\\\\\\\\\\\\\\/lROQL87EQWB4m6M+kMDhZFI2Xhv5dlSA+RvnD40KGMqYgYhuWOoQLLCiCNNY+LtdRfAXY3XG06MJ58PgvTVg6+Vq8B1lDjI8nc20ypRCRawL0UNQV2OGbrGP1C+OKZ8O27zxd0QF\\\\\\\\\\\\\\\/429yZoPMwCSTt6FDf3XMSEAL06WaJtF0y9KdC8055K2TtSDal70DGrSY1CH3s1pFZ+Flv4uyCFuqV85zHqBWTBxAC9WmqI9ZuOqjn26HjYQgnPMkuaXsjisVRs7odVrEiWwH4kW1GnOHU2LxW+EczRXBRtZqGKUpAwbvUUgof0PlbV08a2gDIygQ9avw363yriDC7YXapavS2kJb0mRW9lz1m32+GNSdHGaH1qD3SuF0xTiEEKMRP2vDZNbmsXWb7z\\\\\\\\\\\\\\\/0vZzICjUKesuyyHUZqKSPdoSIuyI8r2opp0zy+Szaw7raiZ4wTCJENHw7SJ4V87X85eZqab5PnxKEWtyPAYIlW7sFZTitP7NgsA3BgiRmWPDI7sCrvL8BCH+EY4b1LKhK+OZPT2bj0LQdPqS4UQA0vm4EHnzv25fmtncEkfe1zxGeZIBIUDFj1B2BiOQEcQsogSqEiWSjvIKswrE0WqPFRfT0f9IyraEIFyAu0FB1tLjfigRVq3XBsxmnSH9QesvZjJ73kWFPylql0z1btS+1MmrFvuNxEQEV1hd9mooHRFYUxsqCealPWFYhpgiMygci+EbMU7Y5Dujzp0pqJOkfFTcpN5vMPulTKW2RI3rK1aKuIImc+l3\\\\\\\\\\\\\\\/p+mkRoGcNS7JgpesXsoIJmWIjOy\\\\\\\\\\\\\\\/SwWHDL8ilQ0w+8UOGjy0JpocYstnDscQyNf5heio5rfaLmk9U0MXgRM7LLnmA5QbFcq34RMstJKo\\\\\\\\\\\\\\\/wRleZTiP\\\\\\\\\\\\\\\/40sSJYBvqt1+m+CJzZr2AAOCW3MOkDMcxmwFzuQP06C2NB9DTuKpWWnOk8WrS80P\\\\\\\\\\\\\\\/M2jcesAx9xw+rd2nPsm2fuR\\\\\\\\\\\\\\\/xMj0kOUIhA5rz4ZVDDVAtK4zSsSkpCHhdHnq+qFjcIktj10y73F59EKUtgE7KL608BQyyV1kGyudPE93C6XxHCP7MYlad8WIlus6cuB+J7N+RzjATIf6D2qWuc9isZgx7TVtNw65kTt55D5vByRbpIwStREIbpbHJnIM6SnFW4qlifOGOYRiLNQwk0EN0JgEoW5TmQJOBleBbNStodJe3TGPSrTk9q36yj+ehTa\\\\\\\\\\\\\\\/nXmA2moCl8EwrAbTnV3lK2PthAF1mXms8KSanvx\\\\\\\\\\\\\\\/wpyVisvg2BesAUo2w2nwWcHvApvQX2tZgHodfUgQDouTo3xh3B1ETPg8ntLUkEpPE+jdH8AI54MDgX37MaqHMo200KAGC9hoTpgEf5Uwf4awQcUgr6CoBkuoAX+OF4Q8+b7F0KbSV+moYdwpJK64MiO2QShxTHjO3p+zNmATc2NRjdy3d2fg\\\\\\\\\\\\\\\/MplyslwO470\\\\\\\\\\\\\\\/jUGqV8VQJfzYrdPf8ZxIEbPDXejt2tf3uc6a13etXdMmNGRNqQEN2cgXYcvkeZAItj1ocwtz5qvBm6JPUEdTOv+GxiYsubPt9U2U7COw92gsBod9YV9XTwriFQFtIuUVTvqhE2XQB0ne\\\\\\\\\\\\\\\/lbSB9wvCPCjoT+IAqaVtWC8+R6JEICgBJc1PvVu1S7guWF73DQUyw2ndawCGVafWvks7pEgfJaWZ6Li+Zd6aKQhyZ+Qd\\\\\\\\\\\\\\\/QHRwMz5yuKI\\\\\\\\\\\\\\\/boMT7NN7U7Y5WkEz8sC9yusW6fvKNNHUXzQRSP+qdz8O50sQUVtq7W9iUenWv7EC\\\\\\\\\\\\\\\/CZVgmXF+zj3pWDtTJTYQtWvNcOdq3lSP25spVjsc7XJXwz3T\\\\\\\\\\\\\\\/23sPe8a3HTKI5DJ7R8TMAvre0yV5hoJTIHxR3vSd2aCH8EIPokhuJ\\\\\\\\\\\\\\\/N2YrzXIB+79P8s5mGyUuTCTKpTgBSRv5bpwuWvCHZ+iPvjyp\\\\\\\\\\\\\\\/HlNDNq5I0VxfGHOqL70nolk+a2upumXJR\\\\\\\\\\\\\\\/CajTwL0Wvi1NnLuxHtxW4P3zL1sPm7Lp1amQ=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022WpKfCxdSPUg3U8Sf9pIQIA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022c650f1d1eb0e3f6660464e2ec59072da9604ece1ed27f0ca9f43bc79e149f86e\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/78.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/11\\\/Suppl_1\\\/78.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0068\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2023-SITC2023.0068\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2023-SITC2023.0068\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}