{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_KRnV2j6OaoIIxt76AbJVZT143yroXCg9nJWC5fgbkZM.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022xVexeg\\\\\\\\\\\\\\\/CQysJxGIRhhtclB5+IThJ\\\\\\\\\\\\\\\/YtfhifVy+GkYMzc0A2ICB\\\\\\\\\\\\\\\/8kksZhLbdaE80CZfvrIseqlwlv1YFRyqvXA6S+nsEnPbQPdc\\\\\\\\\\\\\\\/GDlZiI\\\\\\\\\\\\\\\/mF1k3TgC6cWVdbsG\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/URMIXwp0FVH+1y\\\\\\\\\\\\\\\/prO24KClV1cAyQfoni6B6xYYNSEZqr9TuCh46Vj1+RGX\\\\\\\\\\\\\\\/2SZJ+LyaoLoA021Xq37qFg+IJt1bgA0diLoo4NPB+hazYqfs27PwaWY2sfkREJtP34hW1WUfflwPdwU0hEfKbbtRQSWo7IpX28HRMDNfPHOYstNQo8vChqU1h5EpYqe0TOiQ6dzKOZ+FLzmSfNHrScCXuNNxsl9+Jj9SE3CCpfskkTiyPeGDUaELaJSzOHlk2ep7evxzs1RctE8dpc4F3R+ihUo\\\\\\\\\\\\\\\/QOqmK1CK2M4HpaF+BbH9\\\\\\\\\\\\\\\/l+q\\\\\\\\\\\\\\\/4qEPISRsUa7WOupId58fzVNeU9gEBmF8FJh4xtDML8OuPPegqANgG5lt90fWZcDnHm2g2aeykemq90v9DEA0IVEepFgwxGiFMcZvAMzKzlFHa9MXgbrmz4RQyMgImXM9bi5dhqPM2eWGF3jVlCThyleSneeFOJShWhw9WtAZPtBtORQW\\\\\\\\\\\\\\\/IpE8pNOCBuldXF53vWKNHpfKTh4JvDaqDBCpqwRoTjYbQxr1AKsOBhEaIl26\\\\\\\\\\\\\\\/f8+cG7Q\\\\\\\\\\\\\\\/haMemULgneqosM5jOzGl7wsmryV87\\\\\\\\\\\\\\\/kGG3aLB\\\\\\\\\\\\\\\/aGVxXqO5CHc46HyRas7pzyfneypupoYoO2VNhWc0Rs84miP4wtTpYGJzEHwog8Y1113el\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/r8ujzaR\\\\\\\\\\\\\\\/hELjirp4gcTYmkIRzheUMw+JkaznjUoBVBRMyETVYCiMGVcx13eQYg94C7KqzsKJ8FTWqgZJq+tqWvX+9fWyhPCyiYd5DzLmXtvFCkfeX8yeTQrt2VEsuEw+zcTSY4xQ5jX010j10TtsWbDgbbLO3c3hoN1uEKnAuD7pV57pOZs9zt8ii9NDxY84FLLDI1O8g+OBJMdBdd5NsItTgYgoHFT\\\\\\\\\\\\\\\/tmo8QwWux1kjGvXElquWvGwj+Hfm4wBs\\\\\\\\\\\\\\\/TSlWsd20E6vbDy\\\\\\\\\\\\\\\/tQxI992fHol1IORywzfdwOe2jEfaZzoUss+p7tAvttwkFEhhYmNvSMiFs2XUiqkTwPXC\\\\\\\\\\\\\\\/HL0IMdkySAYXtbR+nT1hAJULu2vexlM+mGJJLyHAsruzcy0BfWH53289+gRMAy1C01g1JwdZnfOQkYf42nFdZBteQtfM6uTp5Xl5oUFite7rWDqicxtrWtkZm6XcB4uHtcIAFlwylmAaETp956bfKh6lVEzPxC4pIWBGkRC2c\\\\\\\\\\\\\\\/oppmd2rkoAVhrspZZ9LpPrjMTisu5+1lFaUGM6N0CojO7jynffYUcVkIazF0PodMWe+YShMImB5igTpkqdh849Sg3gnJoAcJbJoBFTA7xPpRypMSSDwN5PdKrT6kE2PZQxuFtcJdZNy\\\\\\\\\\\\\\\/NSPkuKbHFHfpRsN3QmOEezfmRPFNweXRuqOEUTMjlKqD2Zplf23L8t\\\\\\\\\\\\\\\/ONP2aGuyNnkYrDUOl+MD+v3kGfpkhdMwNjF6txvwfrBV32M11LphZBdS9tOAa202eqEHUEnEuwJ6z2p5Fi8AIX\\\\\\\\\\\\\\\/FTRIsQo60bIutVJDU1vz2ulFAtY8Jdg7M3i+RCb1B33Mseg+h\\\\\\\\\\\\\\\/YdSS8XAzaY8z0FfyyPZlMuf+Kv9zW\\\\\\\\\\\\\\\/NwiGid9wvIe\\\\\\\\\\\\\\\/uDCI+j3q8669Z\\\\\\\\\\\\\\\/lQnyTHHkFFtGVRq0620XQT2zW5HpQ2yO4yb7XwXobV7Vep1LsS7Dxxi7bVXR\\\\\\\\\\\\\\\/EEHudwNIBXloGR\\\\\\\\\\\\\\\/afrEO6yYroFpLpCrnVn0EoR15lJImJEpivSAqmesVSTXdRdmQ3eQZ75\\\\\\\\\\\\\\\/Vr04hnOU\\\\\\\\\\\\\\\/Emp7o6Mi9NxqF7AiOK1DGw0UXYp3TUkiX\\\\\\\\\\\\\\\/Ouq\\\\\\\\\\\\\\\/MwFEQg86mb63AltFhosmYDukSNAu8Vh9Wuiea\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/QXMgJyurOLauCISPtvJbbaBH6IxSNOZTGSgLvyCmErw73jgyJkX5h1x05GUv3DARQLIl+oEOySgBmbJN\\\\\\\\\\\\\\\/KdUPf\\\\\\\\\\\\\\\/uCvDY7dFaeZy9Za6V0aJGzp3ea3s6xw6rbRw46u\\\\\\\\\\\\\\\/UDGNqZPAFYi\\\\\\\\\\\\\\\/3TTFfIZcaPPVDPb8blqCUZLwSftxWpj1LIwhVTAGMA3EGWg3VVKH1LEiciwgmmszcVmNXWc4EGHmjtrjgzxjXQtQRoBQIX8QGoBuJpo5JZU4HhtcK2\\\\\\\\\\\\\\\/sIxlzXbjhFwPQ7WOmpYAvxH5T209kf1Uzhc4WiTfDgFdDM7SjfbXS\\\\\\\\\\\\\\\/5YQCesg1r+xKiizs+hYLZHkDDz8i3Qk0w6TNhsjxns842vpcEUsaiMIM8ApEV2jaGO1Y9B+3P3gK8gBnOnD6EN4JqTWaZRkJWlju5ZXeQ9hTLyT6yPY6vbS3vpCKKwn0GCcm3VKpAkdLji0wVO3rCcyWjT4\\\\\\\\\\\\\\\/JAH+DRMXkHDYnJuZujc+kR77c6i8FSW7\\\\\\\\\\\\\\\/dfjxDEBfO058Xi9MPXgb7pjRc2qQDjjwWxnMrCwDen\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/ukd\\\\\\\\\\\\\\\/jbVFFvM0FwJMkEs4SGVVVHiBrg\\\\\\\\\\\\\\\/wa9xpw+Wv\\\\\\\\\\\\\\\/1Kc2G1maBU\\\\\\\\\\\\\\\/k02cwULQmCZynD2kI\\\\\\\\\\\\\\\/iasxU\\\\\\\\\\\\\\\/b1PBQqpqasmEhPUjM3AdK3diImZFBrBokCSA66Mp5uu9BeCa+rL1pIJYJsd5xEZD9kIk9VA80+x+paLC2IrI=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022Iyfnzn1TbELJQts7mNMTFQ==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002235d531b0e6118da8d72865f3841d9e2024f983e24c3cdba3c14fdf0bcc2719ee\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/9\\\/10\\\/e001694corr1.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/9\\\/10\\\/e001694corr1.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}},\u0022markup\u0022:[{\u0022requested\u0022:\u0022abstract\u0022,\u0022variant\u0022:\u0022pdf-extract\u0022,\u0022view\u0022:null,\u0022pisa\u0022:\u0022jitc;9\\\/10\\\/e001694corr1\u0022}]},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/js\\\/highwire.javascript.pdf_extract.js\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__aRHiqc_vICBvSio4EV9yK5gvHQhdLEYqGbyBpwrSoaw__yvqPgQIYe_eVyaoH2Vmp1uUxhQZL69H1fOXqYIpbw-c__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-markup abstract-with-bc\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022highwire-markup\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-001694corr1\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-001694corr1\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-001694corr1\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}