{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022jmrZyNIEZfdknvDLIPqAt07lKQFkTZgEFexuXWtmQ5aq0vZdEGIHHB7eBNdJAf4v2nNEuaiEx4zhNIHsdhjAHvb16Pb2a0C6hi13F7wZZJ\\\\\\\\\\\\\\\/4Fw+xy22NglbGC1OiZauGF7MGrLk1W1GxPG4kQNtmsa+jIavIa\\\\\\\\\\\\\\\/rxGDfi189f3JyI\\\\\\\\\\\\\\\/yVkAtWreliPu29XtC18GTXWwlMAuonYvjQpFC1kuSByOHqC5pR9U+j5pHV5dghuxz9KwCe6Hme\\\\\\\\\\\\\\\/LaIf0aRGwZGVzv3OXa5+cdtZpTZ32VDfVxGOCa06wtkQzG9CVQtfEO37JrdFCLhQiHNwt84Ivu3hOimyQao7vEJQx8V\\\\\\\\\\\\\\\/PTXa1EI5dsqGsYYlykbQdk7w+MlCeWSRwHgywNwVg4KoAu9NCUcOD6D8N9UvrvOVMmTomDosoMoxZcWalMU\\\\\\\\\\\\\\\/vkgTHE2mxi4eeifW+S+yHYmiUvgXs7u2zbLj75sYVgB2cjAP9xcco5IBPMQuYSjG6FeHSyj38DhbYnRx3s7c62UfV7V0bkUDzOUJAEtzjNhGZgVsy7Qzgu\\\\\\\\\\\\\\\/ckVZwoTmQpxBhR3Co9pJpYXyETLY9xlj\\\\\\\\\\\\\\\/l+nukyX4OKMS0QhglJ1yJr5NpnCLMqDe7axgAn4OkRw\\\\\\\\\\\\\\\/gKfbLNAjoo9D4RTq9Ud9sFkDPxeAOsVt7CgL1WgyoPfTEujkNsvQCwTZJzsnbFi7HCldqvD5chqKE7QXGO1lCAS18w4ERNUcTTdEZfj380Qq+\\\\\\\\\\\\\\\/EwisIsqQY1jJ0qMLpzanfaodg87C5iDhJ+SXP8uOuDcvX6GHjMaJ3x3KoeI0PcFmqJvqDo5DlK+ERrOBbiTIoBSSTKfX34QsisV9GhHOv85eXHXU5W8\\\\\\\\\\\\\\\/s\\\\\\\\\\\\\\\/b1GMB7Tuh6ojvnAx3Gf5a+Q6B68jO5ynsFWas9V8qVZyVGnXBeEs\\\\\\\\\\\\\\\/88RKNCUwniFZoLG8aDRqj6S3Gt2HVyVzF0ad6D1hrgTsabmlRD92RnHKTFU8Wb+mu9YeEy48Il1z8cElporkvBOXcfAKvUi8fLttI91u4HXtSFnI8fV2EkVpZ56QciQoZhCkpdfSxIBh5hFWMp4fNrRii0OWWrj1SPDbyFg+Efvjh4kuJ4XasKYnypS+zkUfXQPN6EXb711gxgpTEUNR7+gtfUHoed0Gb1AukHnfBdokuY3tIg75t1sUrslH3dYntG8DO26LgaIFlIN4+LxYtYpcfAPf8A+eMmjKdLWp9kjnQbiMMUwgPKhFcpwaXak\\\\\\\\\\\\\\\/fiVSvg\\\\\\\\\\\\\\\/cwpuOydyEUJRNic\\\\\\\\\\\\\\\/ygZAneukGP\\\\\\\\\\\\\\\/Fv39FKh0Bb\\\\\\\\\\\\\\\/p\\\\\\\\\\\\\\\/BFwImY\\\\\\\\\\\\\\\/aGml3KZAsjsCh7mzCZb39AvAAXWH6sdCDZOxDpTp9WNr3qAq+ViwTvX0FhjDdKeSCrnE7Xx7f+F9kk+X2+PaVx+wiIXnfTLzY+1jE6GtUf+a\\\\\\\\\\\\\\\/3WIMCb5AKuKeB+h8T+Ko\\\\\\\\\\\\\\\/NO+yKbcZjAPHtuUR38mL0VmpJyoOP1xigK6Msb8CYpN+Zwz6eVDrPfBS\\\\\\\\\\\\\\\/HC+h2Y8XhOIuqWho5XDX\\\\\\\\\\\\\\\/vUJDa9Plo51exChL\\\\\\\\\\\\\\\/118BBgFRIKmTwF\\\\\\\\\\\\\\\/YTeLvkPnp7nOt1A1WU1Vx4dKyvLX278WMYlNDPkYBlrUgVcHF34oDZV+OjfaOvhMXJkUSljyPCBUKOBGwEi0ASuAfSLx2CjhjubBmjgrUqDnbC7beOg\\\\\\\\\\\\\\\/NkkNqK0TAY6lC8B4DanR3OeFk0h0Dbw83NYIHToUJE0MFg4DTxjXhIrDJvVgQchAMIxSgIXS89w6y589len15Al2My7U6hKVwYQ+\\\\\\\\\\\\\\\/ALxT82YesVMMOWC5ZkmkCmrdUc2t2FxVRqWh+6GnC4DbR4N\\\\\\\\\\\\\\\/m4ZyR3\\\\\\\\\\\\\\\/k5erqwwLm\\\\\\\\\\\\\\\/7Hv4uoHo3GhwkWf308Tp1pUNZHqrEm4K9w4BkF8GJsr\\\\\\\\\\\\\\\/3k8gw9Mm8b67ubgAoIhl63g+FNe2YT\\\\\\\\\\\\\\\/WSv\\\\\\\\\\\\\\\/7xt8rTrtnAjl8pXtui0HIbgAeF4p151sf5ZapcUJU\\\\\\\\\\\\\\\/0FjTkA8GAmb8mHv\\\\\\\\\\\\\\\/qeFV3hbsUW+HP5lnmNnrNfRDapuH4s\\\\\\\\\\\\\\\/iE1WNa6J\\\\\\\\\\\\\\\/xDTp87XYFA480cfItHzT4AsuHvPC\\\\\\\\\\\\\\\/AokTM8cRz5+AAv7xbV6ylQi7a3rFu0iUeFPp7dE9AaR1PB4p4\\\\\\\\\\\\\\\/BLtR73XYNMAEpsroXPzYhdExP+hbBOzuRbY9x6fUEOnhufO+sZTJiKA6zUshpIwWt\\\\\\\\\\\\\\\/fY9kpCWsw\\\\\\\\\\\\\\\/yKsGdhVcAcZOLDu6vqL\\\\\\\\\\\\\\\/PnKDfO4NNFHZQvvF\\\\\\\\\\\\\\\/+CnmWDK9+7vxOGxg1us18qZWKhbSjZulBYBQiwtrsPtsNmwJFAsoZbxgo2tKWuSyMH700MONKYWbZZE04bB03PFNRhETKXSJbILDWG1nkiedRm6zfIsVvGZHDWtEd+AjivDh+k\\\\\\\\\\\\\\\/lh9byy6FBrbZ2oH8ldrTGYhDTKSAhPtauq849l3Im4u4s7ls5x5HVeKR\\\\\\\\\\\\\\\/bjJb26EpUogdECvUW2EcDj1IDIkFP6Id8a\\\\\\\\\\\\\\\/5tx+2a\\\\\\\\\\\\\\\/e9OeVH3257CKPNM4y4CCV5FkeHXKkOAtTNiUxCM9AOVpaHVUH4FOyC380mwYnbf7Yb6wg+77InBqf+h2yfx4pPMC7Ow4\\\\\\\\\\\\\\\/B5TKQRaxZIzRMVYbcuyUjOq1CUvONCAs1BhXcwQcWJ8EV1XEgyOWnkfx6HTUE1e80i+JzBkjUENbng6qBduRMwgYMSb+XLMcxK3z3RjRd5Ao1c=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022aTzy45CUJNmKH0WMVbRg3A==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002258bf265954cc64f86b05865b16b89b844d8c85ae9f7704f372d19c01b6662fc2\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/9\\\/3\\\/e001831.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/9\\\/3\\\/e001831.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-001831\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-001831\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-001831\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}