{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022BspZqINFPF0VefbDQoVOJihCPDznrMfMfYpTWyWQs73NgwgzUxlfKyM4CqAh8hP5KdzLp5qaiQvEaTFAxxeDrJwKZ1lxmZwSCpEaZ\\\\\\\\\\\\\\\/SNnS8RJYHhCuqVVJSvQJaBSZXz78pdtviqvkBqPfiMIdIJqJK\\\\\\\\\\\\\\\/yZiUxH2WkB16zFzLf7Rk7k71WfRpJ\\\\\\\\\\\\\\\/T8ZMz\\\\\\\\\\\\\\\/pUhD1SSdGx7OBFeH5mrN6zCDiyZfjXZqcwQTge+Y3JzNpc8UlgJH3NoMuVxcePIYTuycS13QkQjn8JvM1cPeATWjIRwETfNEwrWcEYJJ5\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/I2VNC15JtfrBiLxETJOA5GVpxzLlfkPJZyfneybuX6H\\\\\\\\\\\\\\\/rumgtdDQCIwwOVLb+SBKV+PnN+EWRxatTOfZ4RTLYUNVKp20thzQiaN3PR3jFhwV8lCXw0bqoIOWz7FTdJv14m+NOGuPyehKQPgMp2gtBYIORZElgPrRTFB9yjBC6vcv+D1ZqJJS0YlePhaSunAb1CTy+t2cJTBxuCYkRg4AbP4KYqMTQKEDv4fWjAqCmbJTlTRJRQqNblYaBLheHgOj3p2peVIPi4qTITSd+Bsm+k0nWDcrsrQfXeqzv62\\\\\\\\\\\\\\\/6epg8VFqFXXPJXZe1QnfKNmkbLA\\\\\\\\\\\\\\\/vCQnfb0V9C1p6va6tk60kTiEHistaw0okcnxko23r8WTin2npQ7m6QEnRonO5Q9n1eU16xFerhDEijaEqKu62vjYTPoJxBafGtHnzngByq2rwEw8gi1sgtsu8C7i54kiCLXAX0BTLKo+k0lWwjYh5mOa5u\\\\\\\\\\\\\\\/i7yH04Eh1VEi74iPb0aYHVqWEPoP0lI3GXuvxhsWY1aS4uiATux37aGUzjQ7QdUhuIdI1TWWtJokVjuErg0y+uaXGQmnvL80AaGnmK2fzUNlj2L0csUDBMMWNh7OzAGV3cg4acEIVR0bU+omff1mKwWqmUGYV\\\\\\\\\\\\\\\/7+LOB4sSK2dXpvI6TUkpqX1BkdwhDu4HEY7Zjvs8vvn\\\\\\\\\\\\\\\/OxCrGqC5qXkf3M69HArBSQEWgHheTSrj7vxnfZAi8VuX1t9zYRhMfVeSH+A41WaGTf\\\\\\\\\\\\\\\/IsmwT3Gx1RFalm4OBHVugxa222Yq6oIu1TPCY1Pa5VCi8dNI9I61Gl6u6zWg8CDwVl87OWdTWckLDwgAqlduH6HFgYYg44R1zD46gBrkzLDywg0+Xkx7H54\\\\\\\\\\\\\\\/shVO7IgdXFrr1Tywp1Lj1oHqWyAFK41Ypo60EpG+iKnV8C4ElM1i5DJK\\\\\\\\\\\\\\\/5A5t+AgE\\\\\\\\\\\\\\\/20L4tdgRXxwcltXXel6e4oaorg5ZowIX6dxDuKQJhnUX7sQ6uDG5lsv2YyjnUmyda7K4mrqKBt\\\\\\\\\\\\\\\/586O1GA\\\\\\\\\\\\\\\/df8H\\\\\\\\\\\\\\\/LweJlNqQl\\\\\\\\\\\\\\\/8m0408dwY0l3NXewkJkCP7tmv4Ztqnxc7nb1uNoi\\\\\\\\\\\\\\\/krzwZhksCc6zU9E\\\\\\\\\\\\\\\/HQSvfzDDeEexVxX0ifR7nDAUXnHDsZayZ+w7lEq6rlKgV\\\\\\\\\\\\\\\/SqtBubVzuRAXaZUV8PKitG2ricFxqlAjM4NG7B5cFELuZqsB15BTcd+5wSsbABNf3ZHSY1pr7EIcG0lTkxe0f8zuginYA1QNS6+DSE5JVqIwSf1xSfymMN\\\\\\\\\\\\\\\/kaLvQMGJtbauTNecxrHZYvl8VR1yaSdxeoALiwa4H5yPreSCm4RheR\\\\\\\\\\\\\\\/7lgJ2i8cGm3l9ySQX2Hbr+\\\\\\\\\\\\\\\/fhoJA0IhmJh89ug4\\\\\\\\\\\\\\\/vDvPVdetEqLsakSBYjHmrR0p9uELvdrz5JV\\\\\\\\\\\\\\\/FgEhTciiAdXR7kD1BXlZatd6+L5hMuEXvhuiZ6LR6AbiTfkGv4YgoTkfrPauMS+9\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/DJ8xsT+tA3zwK3net6rDqaZCQMYr+Mg\\\\\\\\\\\\\\\/OdFsm\\\\\\\\\\\\\\\/62hCd\\\\\\\\\\\\\\\/uxcLnE1rGGryCEihznLCziCodyIqy+RDJ\\\\\\\\\\\\\\\/Dx1PDjvvieqN3z6B4ZwO5VAqps5kPAQrre8qPJPAUNyav55l317U36cudSbR+p6RWWZG99zfYPznXPj3tNCTgeoSDD1d\\\\\\\\\\\\\\\/NGWzpYDvQp0hNa8IK7VxZ9Pc06h0Gnd5J63Aiu\\\\\\\\\\\\\\\/k\\\\\\\\\\\\\\\/GangUQhXWJ6nvopygv9uYQBVb2t6TaT1jNPHvnh3oKW4ktjbWsi7L0LX6VDb3kvuClKnbvvnBlEoTCxthtNUnrA0f2hN7e2BonI3YGIauFmfVXZi6\\\\\\\\\\\\\\\/xoef7xisJvANpIecG\\\\\\\\\\\\\\\/5PnDelg61Mebv2Bv+XH8gnlHR\\\\\\\\\\\\\\\/rDLLBCQnbckEU4wmjhu6AayHKchRxwytXIzPnbVakJjapzRqSJ9LjDsOZWyTc\\\\\\\\\\\\\\\/oTulf7iHJWFdHSyytqThjocdIkCS+O6lc0lp6zfiQK7nH\\\\\\\\\\\\\\\/Co5sqwtjHxPwiYHMTA+2dt+ylK66zYJqIp8ztQXCty8GMZRJk2v6YQwxEWqrR9drzutTkMYzeV27XgPp08querCnBOwgHXntwwixMWwqrYaepdkcbilW81MBWDksQ9gWI5WozwEq+pUSWfwNBW1kYS3JmhbQ2C3z7IrG+std4K2DoaI+er6FhnUWJsKTYIUyeuiyGwGtpTIA58QmXL\\\\\\\\\\\\\\\/7gs3v+zvoUz4tojqfeUZ8yq0\\\\\\\\\\\\\\\/6yjPxWJqIYUUwZtjX7LfPJjQd3QD0FDAV84cPjEYdXL4siRkXvypIFOs\\\\\\\\\\\\\\\/x2Yuq7wv0v1f1ecTekRh58KfGd0IS8CMGelm3OtSK+NJjrBToEd2mNqVs29bZ+V69MT7ASyBLPeqAIsK2K3dFM=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022qefNF3gQt1NT2mhqsZuMQw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022d4eac5957e63bb15853bb572e30fad35f03cfb6d176a5e73ed4e041d6ac86b59\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/9\\\/2\\\/e001230.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/9\\\/2\\\/e001230.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-001230\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-001230\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-001230\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}