{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u00223+RoUlyvq8SFJYyfrcl4O0I1ePxs2\\\\\\\\\\\\\\\/VJ9+Gc8kXYUNQKwIZ3C6M2HXI3zQBaaNeTif226v4+POVMqlza9wD4XXvN4hzwlok6sZvXzcUK1gY2EHSfnLIAHCqOARp5WKPg07sOHhP3HvzF+hycspEnxEXq7qMm+e8vZYhy14kcXtswt9RNQuulnzez\\\\\\\\\\\\\\\/ORkA+sgc7H5DqA1erAx0bbrCg0QLrMj8KcsiRGiB3o0LOF4h3hc7oEURqTgIkwKFIZnrb3VyMeiDpJ4oo7AFler+OYPfThh07WDNzxCjWds9qI6yxa4jYPPuNu1MQiaW\\\\\\\\\\\\\\\/Mzl\\\\\\\\\\\\\\\/2ibyn7S0pslifNQ5fxlRyos9\\\\\\\\\\\\\\\/fNPthwaU8fzp4wByMWgRO1rHpn3rFwycuCVazaC2GhxQ5ayWVPumdvLg233WHISkUh+0HgjpKtfgjsn9b\\\\\\\\\\\\\\\/KeFRiiC9hZPMgj5OdBIFPA5qX0h4CtYXKZouvDA05zMKgkb86eapgd\\\\\\\\\\\\\\\/9RJ1oZkiDoEKdZyxP+XNyXh1tMI5yljLJUl3L+4Q2K4t7vqfIooqvO66XFIKFOezY6WDCrWkM3\\\\\\\\\\\\\\\/mYJXPj0Sk+2aKJhKr\\\\\\\\\\\\\\\/TUFlH\\\\\\\\\\\\\\\/8q8BbDELiodIfxHoZo5YJohf74fDU25KuBoFFn8\\\\\\\\\\\\\\\/wCgeFORYuuj2DF3f9C6lTwk4vSIWvPbv0bkgw2yVEy0b7O22y83\\\\\\\\\\\\\\\/RS8sbopYxQy7krLnJHQMwcdtiKT0mE2ONPTB5AoJt7ohAmww67yMEWTaFwi1WWqJRQJ5VC7XWpjhFIpkYiJw2\\\\\\\\\\\\\\\/oV26C9yjv2vrdLxLYeoSePPyibaPCaAutD1qTl\\\\\\\\\\\\\\\/QsOlBeQ+2gpsTx\\\\\\\\\\\\\\\/+tNYlRSetwJqcGAu3EW4\\\\\\\\\\\\\\\/JDDJkcS85\\\\\\\\\\\\\\\/XkWZBukurKUEYLRHiaLmhfz0D8SGB\\\\\\\\\\\\\\\/8ak+jGk1\\\\\\\\\\\\\\\/nEfy9Wt+mjLC44gXG9Gno6iQnj5yhZ2XdW4nZ1f1JYX4e7roTxyM0Zq3rd2L939v+\\\\\\\\\\\\\\\/Zm3bfIyFfHsdoQGDmnoziwj4MHmuf3dnyXff1AbeUPUjMNXBf1cVsDq8glVyg5nAKVuFoJhC8cQ7OaWx3dc8S9K2NCSC4IeVxrid8mflEL7dpV1h5rsBYdusRNdQ6JwqaCZROpsPiL61M\\\\\\\\\\\\\\\/0KMZ0ihY5VWOlL4ibkwboKx3EiLn3pVj4u7dNHGO1gqKEWOu\\\\\\\\\\\\\\\/OLBJ+k5d1a0fQMXF+f7\\\\\\\\\\\\\\\/oYiW\\\\\\\\\\\\\\\/Mpv2TOljWbWTVs13d7ihJt\\\\\\\\\\\\\\\/k0hzrRSFr3wjGSgyfVLr96OhAuDO4BX4OjLs8AjsWAOcBPNMc6QjtwiTMaIDcjI3LPfhABB7D5K9QOlm9LGcFoP65xnEfRHa+wQH2aYTWzUfhiD4r2vxN3YO+8kJ\\\\\\\\\\\\\\\/zltMcPSnSObBbbHH7i3C7bTnqsoCBIhaIvYW\\\\\\\\\\\\\\\/acz6Uo+vtwoRBkqk53PTwwSirjWDAwbC4N0v4jAd7JYXOrC66rwvDx1i+F9gpRB7xEthZeSbUIIME2G8ytxYEin4wdI2VedME5egffcs+mXnCkjB5h4xPcOiL38kc\\\\\\\\\\\\\\\/TSVBNRK9PAEntgoeBRhCoyNuNNMgAF5wwVw5ZwzFSj61Hd3GuvFf9G25ZRSI11gXnXZdSX5YMPey+QeDpg0tKJceqjPyUt+Wq2v1wehl68bvypS3Z8OqzbMCwJi+ivCmIfAOrXYpg6ZoFgtLKBVmJHlvyA8YML\\\\\\\\\\\\\\\/K2shUv\\\\\\\\\\\\\\\/3bObTHlp+88HRBX5B76bwm\\\\\\\\\\\\\\\/DrgqgtxdHD6FI5vC+0InnX4IhqMY6fmFyNqy+vjLp\\\\\\\\\\\\\\\/zcvDsP9kXDSzyFh5EUo4b48I69ghCnWm94Of2+IFQdVDGK8AsC3VeK7oOMSRilpTr7SYnucYP\\\\\\\\\\\\\\\/Lc0xNdYJIr2f3w4uREBpOXiX+vvPyNvwrAP89nGNjxbcS5izZ9dkNx29zA1EB8pRUGWJAgGbythYL7wZTdouqls75sPyipEpywDZopFEZfcxKCSR4xXoQhqlqQonJlMN1VaLrrwFuuu8BiC1g\\\\\\\\\\\\\\\/I\\\\\\\\\\\\\\\/c6SHTvLINQ4A0QQogCsX61XYtt\\\\\\\\\\\\\\\/a2InosT\\\\\\\\\\\\\\\/eB+D1ZvWnW7g2vNYEH74EFbx0Dw4aq7p3H5Nr5lThbgeG4mYwAtdMQwJyPjfm9Wbi\\\\\\\\\\\\\\\/8Hyj2HQ0JRQXzgVukqTwzomfTvIfqJGLBSYSOqEr8lHivvH+NNchopc3ZQmeTHoPOPxMlX7dAgoxpCwHOlYQ\\\\\\\\\\\\\\\/hjPC4NUMqavUspCWgJ1XokpqkSamBkbtvqlQQqJgtygVIZ9Xba0pHO3NN20RRN78qD+WzuC3ywL03aXLHhyWhnMatfJbvfrBLgNliIG6iZBY1TjuWYSR\\\\\\\\\\\\\\\/DBZZ8HeaN\\\\\\\\\\\\\\\/YAatp1\\\\\\\\\\\\\\\/ETt5w4KFLY4256+bMZzyq832aUlffAveQYzI8PRKXzIr3GCtEdhBrJsQWOKGNQc\\\\\\\\\\\\\\\/dxNtfHdl8+TljQwODnCww8XwEZBOasjoIU\\\\\\\\\\\\\\\/L97wupuTl4Cjewj6QLldgz4z0L\\\\\\\\\\\\\\\/p6pNw3x7h1R5JPysX3TSZ9tobk60Bz3s+ektA+8oUTOCR0Sju2cCOA9AzD\\\\\\\\\\\\\\\/XoG8cXcrhYK6NXMii7YOYlbqydZcCL4ToNlhNI3VeGwXBA4Xf\\\\\\\\\\\\\\\/gcdrGc3vmUV+AIlWQqFvQAccKvzxjEwrjsOIh064yEDvF1jhuiKiN8Dyl2rBA8AvVbfVgMV\\\\\\\\\\\\\\\/YMi1pQ+DkgH9HvWcECVnFvedyLYxTQ\\\\\\\\\\\\\\\/zxmSxz20bQa7jVeaTU=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022b4yv88wr8igLUMJQCUyNFA==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022cd53cea1c42bdb0535c3c9001bec61716878f2324c93f26dce126dd6297dccd5\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/9\\\/1\\\/e001460.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/9\\\/1\\\/e001460.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-001460\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-001460\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-001460\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}