{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022Mlw1HMNGaaI2346o\\\\\\\\\\\\\\\/3N8nVPDbBs8E07Q5fbDq\\\\\\\\\\\\\\\/vgD9zg+Lfrg0jT4KU0hTtJ6voCP+DARkcxQ3WX1SG7B5df3RSe+HeLzQJKxZcqpLMu3USsSB5AsYf2aBO4n1w6rVB5FqMS9XAManjVUU29869b\\\\\\\\\\\\\\\/WWfdaLJxt+2l0uHbI433ctWaiUX5mOfEvcRs\\\\\\\\\\\\\\\/dEFdJmq8iTy6IFzX4vuijyVIZ7zybis6wM\\\\\\\\\\\\\\\/519JrFOz8lWe7KtcC9OFh07S0\\\\\\\\\\\\\\\/gJ9kaDiqN1593USwjR\\\\\\\\\\\\\\\/w6Ie2XIgB8zZHP\\\\\\\\\\\\\\\/QrG1Ohkz4tsAt9WtFo+3Rhlp\\\\\\\\\\\\\\\/a2Ea0Bgd\\\\\\\\\\\\\\\/2yIur2OC4F1FHnhGIMOmElkopSzrWV5Fuizky0nf9Ggl4Yl3S+\\\\\\\\\\\\\\\/fvRr19WUsSouM1my3c87Wm4Bu6amLS9fkvTVdzSW5oh0Iz\\\\\\\\\\\\\\\/7KDq9SkJ3viWy34tF0ceiytxrOvdp\\\\\\\\\\\\\\\/J0Xsg+wE9\\\\\\\\\\\\\\\/n26xA2JP4dfDLw\\\\\\\\\\\\\\\/HBfZ7\\\\\\\\\\\\\\\/fTA0LaYEVxHTq1tPBWTWMZf6U5ILZngHhtjtVhX3vuh7AY+9gBZ7\\\\\\\\\\\\\\\/IXwh7CjkEy2RZlsoJ1kzGe+qcxKg+YSGC0VE4FkTO72KAt7R5DbIPMqqt+M+26sO1meGI0CTNyk\\\\\\\\\\\\\\\/a8gJcOkFhKxFMEPSfw\\\\\\\\\\\\\\\/ZT82NKq9qCjLZIZWgYIbL92Wy15gto6Jpn88pI7FxsfEBE5uGNj8FNeDjL7YZj+46N6Iwiz0UvvpR1Ovq3A3R7Rn35TkXR\\\\\\\\\\\\\\\/ifEh7OD55CbIO9stoSzjd3YHvXZyvXw0j\\\\\\\\\\\\\\\/IX6UJfAVqYzqGbn0A2VRvE9tIdUnKrQMCjsvQGpO\\\\\\\\\\\\\\\/5vVn+Y5Rhqz3MPpMWBFmRG6TvW+cXnvLlh5e9MEzBIa+NGQmVWJsvAnXrv6rom4mIaXkQu9Oq3oKA\\\\\\\\\\\\\\\/4lWwlTYh51QP4t9Na5j3j69k4YdbrRgEffF7cesUQNyuY+TE\\\\\\\\\\\\\\\/HrjFu0y8+MOJnM5ZN5NigdMdo7zmkGsuPKF80DJaSVZJ\\\\\\\\\\\\\\\/IcLfF0tLevwaSYG3FIBMW0FKeQeTdGhhcXpxW65l7FdkRR6Rp27+3NheKEBb\\\\\\\\\\\\\\\/nEzumoehsyDte2y1O3hORZD1SAFHrob1DOf5usDI4VyqNow75+CowY6HvMBBrCSeLirhu3FkCAb0j+GVnsl+YigpA5awM8XQnNauIcdoZEfn0UlMv7tgL\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/sgh+0gS7LjwFJtGIf4LaDC7ar4UCPyMrWY0Q\\\\\\\\\\\\\\\/hi\\\\\\\\\\\\\\\/r7fJIeBnvVhBG\\\\\\\\\\\\\\\/yLWlLoHNsMz9KC59WwGwj\\\\\\\\\\\\\\\/oY4Whn632CpgAp61PFQodknqM\\\\\\\\\\\\\\\/vl3Q1bojfPjNf3rvbf3V7zSEc\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/GH9iMlWiVsFagPyPpjjKnaT8j8\\\\\\\\\\\\\\\/duQdUXzfFcw7NpK\\\\\\\\\\\\\\\/UQUXKJBIqXTVe1JygKBYf2+0dnHHOTBUw3iiZrfMSUXDZmLn5aY59tXWMKdfTt3Uw0OLvhhNq0VaaThKfTmlt8GzOkbasLdrkv3aSgnkpNbkODAZ2sRJ52aPN9Tzfj0fovD09b\\\\\\\\\\\\\\\/fBAjMTkwJO\\\\\\\\\\\\\\\/dYUPWtcrbsjm2Ud6NG968HPtCDLWMDfFh3kXEEjPJbAikDdvzPApWaYJWeg7swU7bz3rP+enRBgO4Oa4P0T8n+1OMK2ucUB\\\\\\\\\\\\\\\/OsbAsRCC3tqqTSIsftv\\\\\\\\\\\\\\\/RKjzJfOcjgpy7mAM4z0SvX0jTm14js7EJ9JayKoD3c\\\\\\\\\\\\\\\/nUsKCerpMQ3Sy80jTj2G8MN2k6wjMRU8ceV4iNUtQhp9j5f5MXX3qA5v1C6xpG8isgNXtKNezP2sNPPxQxL1U8qBtm5x0Fgq+AwZG4aTmCXgZouo8dR2tnCW0R0dxtT0YeOE08hfcV9kSPMy25MNhYYiTFi7E5x6BIlN3wGFbADPM2j9VPHE+lqfH1W0lcNEqUUA2gFyiuCEgA1n0eOb29EydKcjhXrWTz0Y9NNWvuJu\\\\\\\\\\\\\\\/xrJsS7qt0blYE93UwUldsT5KDytYmWHCWXzTuMr5ETsXO6pnLrpVapTnGJbt5W4FVzcRlPua+MaPhMxW19ifsP9Y5heXWHnTy+B7WVx5fui21PNNDr7bjMZtLwZ+a\\\\\\\\\\\\\\\/abf92MKj29tY4xDy\\\\\\\\\\\\\\\/L\\\\\\\\\\\\\\\/HyfdJzzSXb8hOWMrGKzIQyALwsBrBD\\\\\\\\\\\\\\\/77DlM5wKn7+E99mjfbguIxhpDkXoK+PSHRDXWN7XWo\\\\\\\\\\\\\\\/OIdLUGw0Xik2K\\\\\\\\\\\\\\\/KzXiT2mwG4DFmze2d2MdLls+LAuE+6zKppiVoqtTpWcwPFJy\\\\\\\\\\\\\\\/KuLSz7MHFCI4noDnuKoqJNDYd7f1Icghew4\\\\\\\\\\\\\\\/LfefYKLjjkJWRn8mXMk\\\\\\\\\\\\\\\/SjD5bUg7CvDb2HCHiHh077T7Kbu9N6M6l\\\\\\\\\\\\\\\/ezcfZTAmVjNgkAbx2gy0cAX6EZW\\\\\\\\\\\\\\\/e+DEt60pB4mGjcxjTD38Oj1KwdTzVH9YBZZLpg71qsC10V9PEvomLxzIf3EWTd2MoH\\\\\\\\\\\\\\\/GAk57Jy0YQLretUNizzrGapF7wnbHtsvotp86vt5Yc+N0UDlxzx60Vx1iS1yoEU9obmiwzar2\\\\\\\\\\\\\\\/8ywXEQwL2d\\\\\\\\\\\\\\\/ujFvgWSULJX9pAK5r9U+Liu0hiaQ8K7q9FYPlu4xpxYawXCk3jBYtL7F8RspLJbUgM6j7w++Sxx4LnhZqFlqZm+N4bebKt9Kf50rRpk1+I2eMvpVl02IyWJreMx6CrNa3D+uwgdR4HQ1HeqWZRuTdCg3g5Gjgw5Z0Ps+wFPotvUO8kvH971tNSZHs1LPFBBqs=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022a778cH9C7VmhTRjnDOqAfw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u002260ddfbe702d9f00a9440ffd35ec779bf0bd97e84747eb579bef4c94ed5ca39ca\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/2\\\/e001235.atom\u0022:{\u0022access\u0022:{\u0022full\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/2\\\/e001235.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-001235\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-001235\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-001235\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}