{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022dZkTuu2z4UIqRx4Wpl\\\\\\\\\\\\\\\/RbNmAF\\\\\\\\\\\\\\\/id7aLSD0g2F1+6AplB6dPyQAOit5RfxSQLNLfh+H4SODzZdhWNlUZbnP5ssIfW2us\\\\\\\\\\\\\\\/VH7NxSZWZzi0BzA9UfCFNUnAHlp5cjNnBbWgRW+HtiI1B5sEljAhM2kvHjs4Zs+s03tWm7PZmioIZN8MQmkkAfMX1ropkN6tl99J1gYyt4G2Ra6kQ6W6rjodMkTZI\\\\\\\\\\\\\\\/krDQIh4XsnWwH7uivv48J\\\\\\\\\\\\\\\/ASnDoTgYRiFN9JwYF47wNP240AypnADQV2t\\\\\\\\\\\\\\\/JmkMOxbpBPqjU10d4xPNf3yxCetD9iioj\\\\\\\\\\\\\\\/YeT5Ruz20NLEpzdkZpwo6SojL8uSJw\\\\\\\\\\\\\\\/bussMh6zZNjxlSL\\\\\\\\\\\\\\\/KA0mz9ZU6Rd41ziZU3ezy6rlis3fi27KwnRTMKXIhnxrchYr+a1J4HK9vt+MtS+Uqu\\\\\\\\\\\\\\\/27Hpb767xTBAmyCZOf94whJ7JN9wZtL26e6SSCJ\\\\\\\\\\\\\\\/uaEGnEqsRdS5l77Io5eeiSOJciYqOMd11EkUFAVsSChtLBElYb4L0bKrxTDfxDVm3JFlp7+ZJHm2jHfTqaAdX8bUMs\\\\\\\\\\\\\\\/oqcnY+0lWC1sNahCEzhuo\\\\\\\\\\\\\\\/3lkWzfB4Z3wHIevA+RRNG\\\\\\\\\\\\\\\/bFU\\\\\\\\\\\\\\\/ySD3C90JcaPTF0dPYWr2+CMA3cU1FNSuP8SaQlGOiRca6FUF0j\\\\\\\\\\\\\\\/XQ6LGHywqlxOYdRBKVUweNegwmA\\\\\\\\\\\\\\\/jPWeQ4axoJyZGGZbTyhxnNzXXc8xWP8J4tQCRoeIqubB5ZBd+dASVYgaPtaT1CKm8qv8HQ\\\\\\\\\\\\\\\/c2ixRFmECYgf+a6FJ02BnJrxjhLBoLRTD0L3+roI9nyoxC6zwScTHR03Fbp3KvzVgFoFz+0PWSVztVNehL52O4E2wjxKGk1TQuksQ54TpEbCChyG5z+9hwdcrqVFrycBMBL7K3bczLX5ojw8YgvE70MIY9E9lGkFqou2EaeOKNY2Q6KXnuRFaKpVynk0sWmGrd\\\\\\\\\\\\\\\/6D0hbhLa1K\\\\\\\\\\\\\\\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\\\\\\\\\\\\\\\/aYICtIYaaQ3mV1MERo8LBOE7vHkY1u4LGch6pJS9GyNnG2nkMYmdtwfbUPn1Ne+6F01EP1Kl2d+F0JeaR7EsGnOGVaN1AGBtmVzLilLQOsTqgZdsqS4Q3C4UCblGVGmzBXJFPx+nXm7zJRPQw9j\\\\\\\\\\\\\\\/aqwHk13j5oyBFxqUYxprgzpWysP\\\\\\\\\\\\\\\/l3qOYJHQ14LcnH1bJz0Rnu2b4B5RiEGlU7XwcJZMJhH9SswfBkRiO15iIXaM6kbDAdBHX+G3EhhdNdEVgtb1s1QrrOVsxTtZPoKDx77I8x4oyF67JfXscUdOQlLUFyZv8vYuJ2nXEEgdze7I3i5UEXE+iyXJ47EhjY1tTmEocZrnKVn5nGQPGfrc+W663lODW1N6cq04WyBMvCldvLBtDZ2JQLQ3+rxV4YZSoYV9Hxj5o+9eB3jpq2XqtSCsKRck7wnp4oFyyz1avjMAm59PjtlKArjkWSab2LLNU15TN7N7lzgvqdnFybU\\\\\\\\\\\\\\\/xzaQJwi7h2SkDBwx7fv1Ig3UjfulnMUnhBJ+odWPQEfP36nv0\\\\\\\\\\\\\\\/p7Ep1Ehe3majdlfi98jjhv+8CVHPjTHjUp1dMTiq2fKlh0CNxxwA3WWbT8eMAJVmv4zZ2hnlOWAjIv3hHqwPWirjQVchRZfnnmBqt2\\\\\\\\\\\\\\\/GvKLNpcYSCqyUMkeyx\\\\\\\\\\\\\\\/oPWIgj+5QD0O29K52+1uxo63DP\\\\\\\\\\\\\\\/U\\\\\\\\\\\\\\\/rcBjD16Yj4tHR2DlQDYnxcrdkKAaKUz+Rzb9TUSBWIU1Xp3jRDL5zriyx9XaNxdD7oxI62JWdyg\\\\\\\\\\\\\\\/lDsPIaFaBN0xYaZScx2E10pKp9P8H4FQ2x3MFIE6V77YRnyhlkNM0192KtDOzFyWxPCtlwK8yhglUTEGhtkM8uvo\\\\\\\\\\\\\\\/J71DeEb7imwy+\\\\\\\\\\\\\\\/R2lc+gAsFGDe1YI4SjWt8ZTjbpcevx39bpuqkvZiJJJt8IXXfqvVNFKp7RsyWD5tIA2qeZH0\\\\\\\\\\\\\\\/atZX\\\\\\\\\\\\\\\/WAwS9sV19dduqLzZNtChYrmoEdC7hHzbe1QgKPu5WWTDVuFHqJCGyJiy1X7MtSR\\\\\\\\\\\\\\\/8KBwZwGPdXAK1S0wSe6Icy9RBVLWreM940M1YYS0nG\\\\\\\\\\\\\\\/p79tGB6S+C7sOP8IPeaqUt3igLOUZccg2b+nqXOek6+3DXnU=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022F5tEb47HLqlnGHoG4Fdjrw==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u0022018a2e9a6632c1461fef4083ce69f0debf5038a8b19a9c9daa72facd3b6ce8f9\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A428.2.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A428.2.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0715\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0715\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0715\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}