{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022u+NolyFfZZ3k+dQxVAcglzwUfhGoYVPn1ct+8QOKYQZpukv42n9B5rlf+eRPlLPg8o8tTn1USUywVmmfrSKDS1NF5nsVgptphr9MGVP3IGUmRUefdbfgElDPURg16XngYE97oBfFxtB9gPtaXB80koZf\\\\\\\\\\\\\\\/iDtH2Ly5\\\\\\\\\\\\\\\/uofOrlHeL5uq\\\\\\\\\\\\\\\/976AfVZilrKZb7yKURxbJ6ftChfdaJIqJPdhyc7F7jlenmU6c6OXRABpcrrqUyp9jm1EMG+K9zPyBREVrQYT25VcMiBJlAAG0KwWHyVvKzp5ys\\\\\\\\\\\\\\\/YSLbAqqF+xTpxoun66Vjmm3vMw0D2AWuo\\\\\\\\\\\\\\\/DkqvZZTKmUn98W6QNC41yqe0Sxuo+NbXFWYqUbuDJC3RtsJrCnxGInieBsz3RmKGmyrrtjKzyTx4AZ56N0zBW9RvCah+v0QM6P+jI9VX7LNeOa7zmeeT3kXz2l+T+voXEI0XfD8nSCodCsK+COCqysrhuLEMyqWZT1IJuQFUUTi+Onn\\\\\\\\\\\\\\\/4Ce22krvEI+zy\\\\\\\\\\\\\\\/1TXGTe32iTCSSp0zycVF4OdOFNrBGdH6MhfDzyF9WU0qQ7cGzgP7udHV0q1plZSbRao0WNAeggAbZC1rbFnPAL82VV8fov1bQAK\\\\\\\\\\\\\\\/vsjKi9IaIqrsPNniet03BeeZ75A0tyRdxx9ClthWxL93\\\\\\\\\\\\\\\/DYbxT5t+ROiiLxl87Hwd2GDmWnzEA\\\\\\\\\\\\\\\/k8hWR\\\\\\\\\\\\\\\/O8CpbuvWuNnhr6FFpbIsl2AHuNV0ONPd5OvGUhu4dAqPPCzVAHLxIYeCralHef\\\\\\\\\\\\\\\/Go83+hhIOgomnyhEWqIxWuGma5jAd94UircZWq\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/Fy+xN2fARuqIX1GMdWJMnktdSGtGOuou+DDBAQKjOHfxN99rn5KBatWAh8q546bh4W8RB3fE7xVKiNIFACdkoE2gY8b18yawe9D4inSMD2U4bYZJSynciAX7Lu6Dx\\\\\\\\\\\\\\\/EuoSrS3txdOwEGC7qTfxlDCSqp6FO0iDOZkeWVI2Dutt1xXLf1Qgqr2fultItcHWtLsq\\\\\\\\\\\\\\\/cauS6RjFYRtfcl2Skka0SCQrOpeSaEHOCkUeObF\\\\\\\\\\\\\\\/Xk\\\\\\\\\\\\\\\/BOYZQDxAmIRxxS\\\\\\\\\\\\\\\/UMaJY+rGc\\\\\\\\\\\\\\\/KRNxj1CTL7LENSMEcDuM\\\\\\\\\\\\\\\/bPK0U0RFG8UHTmV9dTWlxDOco0ZCrOKzC2LQQYfkNa7c+iFVH\\\\\\\\\\\\\\\/vd+honHLobXpjDF29RA\\\\\\\\\\\\\\\/QDE6TiuYRuYU+QcXL8qKvxxO39YLhetO\\\\\\\\\\\\\\\/bWzT\\\\\\\\\\\\\\\/2p7SYsWsqIcmoYvVWOjPtJLTyc7hvFeUUUE770LU7d2jIR8XfCm4Ru6MBQ3fsTa4yQRf8JYPoebdRcdKA1NFSxbd9YVqljEI0gZgxgkepdSo5xPmxYUOKpFCftfqEcp9JfXHtq7gTgP\\\\\\\\\\\\\\\/mJqjb6OI1xbRbmX16X3Ca+LflrqB4amSRan4S9ARxpS89nXZ5RcpfYHTIf3IXATmrVnQEmHvaK5W1a6nVXHYurUVM3w3ckcXDSlPTt6wV+ROTDwC+XT78Et9mpP0bx2udC3DFuzjer56JgmjkHU34eKFmFCBn82fxWx\\\\\\\\\\\\\\\/xAYXyOshxgXy3oA1gnYa8DV+TCkBw0dAy6xzGq5uAC+3T+AwDSsQ4kGa52Ik+WZ0TcnRIhtYZqhY8Yr0Rljweppa0gVtIBOhLB69wUe0XbngA+KLBLSln41KM4olkCOKzQbjE+OnHi\\\\\\\\\\\\\\\/bpD5dwkr5nlPoE\\\\\\\\\\\\\\\/S+VZZ8olUpgYGvOC8+VQ+z17l6lQ\\\\\\\\\\\\\\\/NcgtplHaQQAQWl4tpoNnLI0HvgPwzo5WB0bxxH6UH3SLQMXyJlHHUok2DCOR5aJw73FQu7y7PKSRjSi0XGQNJvoHf78Py4J7lFSrE1gRkZOFgXlmY9ZIDqsLYalWkZcAqlenBVmI7V8hrOf+ELg3x4hAZLwSDp41uknzOlqfshePQYocNzp9RyveNLYXRGGb0gArm8MSRCZzSJzVyirlpTI3Wy9le\\\\\\\\\\\\\\\/IUip3v1nO9LWLQtC+R0kf2GuzCSd8F6Rm+jndH3NCRlaTpTs2WLJhA+oZPM+FH83glZl22uBWwuh7r6qFxUwklqi0oBpwWWoOfSWJ2Tj0GRHsGxu5DtfRrnbaxezgtP+x+BCZnCIN7qfKkAxvtC4bv5i1jDybVRwm0JYw0Y9dEqKipZ1oJgmzezLJwtdcjtuDeJg+TFKNePg5zrbKPTT\\\\\\\\\\\\\\\/bZN9pJEYPHNwA1fby9lPbAlnbc1Aa8BMcFDJF2IWqDSdcyN+42PDnkYG6Kne2r5sq8GsdPRlSaBAyZRVZEbQQNVXaau\\\\\\\\\\\\\\\/bSgdyjju25Tb9q5L7GrdmsKzRh8zeXLiK\\\\\\\\\\\\\\\/U1aLlN3pGlGodtMfihsnTijNnxie+LkqoH\\\\\\\\\\\\\\\/pzNKFG6ygleq+46gGtqVYTaYL6824p21OYD5W6ABxLNUESuP2A9VM2IsA8soqhaUwH9t2\\\\\\\\\\\\\\\/G0zEbt\\\\\\\\\\\\\\\/\\\\\\\\\\\\\\\/GH3N3j0vO88EGwlNzqg8fBFFDsTum6aUVO5t8zVDZSHz6I1SoIDoTwagXGTphbkp87ku6lSLe1aWgC2jcY+n6NovBxU1JddCQa8QzRhgXHHGZ12gHk5iU3XlwMLyLP305LTAwGoAK\\\\\\\\\\\\\\\/n0NSM8Pse0cnIRtrultC2krxWWcJrcdTf7O\\\\\\\\\\\\\\\/I7xeOd\\\\\\\\\\\\\\\/VxPzjMH+c2wF1WhClmSK7t0POCB+f7gaiXBt0g29uZKhtXk+SyfmzicWPrlobUCav1tvb\\\\\\\\\\\\\\\/304+A=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022XqrKyLmsmX7geW7g+Vuw0g==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00228636082c84cb6350a00a95eeb92fbc619f01319792a14197e4dfeaf0109aeed5\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A411.2.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A411.2.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0686\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0686\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0686\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}