{"markup":"\u003C!DOCTYPE html PUBLIC \u0022-\/\/W3C\/\/DTD HTML 4.0 Transitional\/\/EN\u0022 \u0022http:\/\/www.w3.org\/TR\/REC-html40\/loose.dtd\u0022\u003E\n\u003C?xml version=\u00221.0\u0022 encoding=\u0022UTF-8\u0022 ?\u003E\u003Chtml version=\u0022HTML+RDFa+MathML 1.1\u0022 content=\u0022http:\/\/purl.org\/rss\/1.0\/modules\/content\/\u0022 dc=\u0022http:\/\/purl.org\/dc\/terms\/\u0022 foaf=\u0022http:\/\/xmlns.com\/foaf\/0.1\/\u0022 og=\u0022http:\/\/ogp.me\/ns#\u0022 rdfs=\u0022http:\/\/www.w3.org\/2000\/01\/rdf-schema#\u0022 sioc=\u0022http:\/\/rdfs.org\/sioc\/ns#\u0022 sioct=\u0022http:\/\/rdfs.org\/sioc\/types#\u0022 skos=\u0022http:\/\/www.w3.org\/2004\/02\/skos\/core#\u0022 xsd=\u0022http:\/\/www.w3.org\/2001\/XMLSchema#\u0022 mml=\u0022http:\/\/www.w3.org\/1998\/Math\/MathML\u0022\u003E\u003Chead\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\ngoogletag.slots[\u0022mpu\u0022] = googletag.defineSlot(\u0022\/21798771943\/JITC-MPU\u0022, [[300, 250], [300, 600], [300, 300], [600, 500]], \u0022dfp-ad-mpu\u0022)\n  .addService(googletag.pubads());\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022https:\/\/d1bxh8uas1mnw7.cloudfront.net\/assets\/embed.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022 src=\u0022http:\/\/www.highwirestage.com\/sites\/default\/files\/js\/js_U2pncm4Q4A7IJl4J_deoOoy8h9tU-3gxfOF4iwZdk_g.js\u0022\u003E\u003C\/script\u003E\u003Cscript type=\u0022text\/javascript\u0022\u003E\n\u003C!--\/\/--\u003E\u003C![CDATA[\/\/\u003E\u003C!--\njQuery.extend(Drupal.settings, {\u0022basePath\u0022:\u0022\\\/\u0022,\u0022pathPrefix\u0022:\u0022\u0022,\u0022panels_ajax_pane\u0022:{\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022:\u0022{\\u0022encrypted\\u0022:\\u0022{\\\\\\u0022encrypted\\\\\\u0022:\\\\\\u0022bkDKE7Vn7066jNcD0xccQb6KN1F4O0tecMX4RcKvHHAE24nz6ZRy1CoUdhAkgqgpb6Hz6p25QIcQ2f61HYtJOIPXX7oQIkGzx7z4zadUY\\\\\\\\\\\\\\\/Br0A6v3WBOWoXs8XrSsUc9ucBY1M3zWjmVtG86TSn68gqFxZsdd3Lg\\\\\\\\\\\\\\\/w\\\\\\\\\\\\\\\/j1PNk6a1Y59o4VrZw6F4EuWswUz2z8DVHwiq4M+0chE2mFA6TATF+a20xGcWIz6hRBJ+8rKJ98LMPA9o9SJ2VPUCPEIhnc3hslka8Vjztk9hNiJ3ZMM5TOV1Pf85UChdYZcqUJkT0z6yfJwgc3jUcmbyKs2ZCoU4eILky8pxy7EHb9\\\\\\\\\\\\\\\/qxmG9BgqueCW7SYGNfb8wDrOg+VsmpHWtJOzI4kvEkd4Mj7w8eecdIe\\\\\\\\\\\\\\\/wDQEisJWpmId7dD0e8SX\\\\\\\\\\\\\\\/3jh9PUA+PD25\\\\\\\\\\\\\\\/Icp4Qk2KFa1WdqZdnyYZIc7KAHvr+h9EZjQ6mdxuLhaKgZoc+gPT91Wp+npLsv4PexraNaoBL8OY+XqygOcWZrfZqfLqxgdRKzaYiTzaHQczmN7yRlt5VyA3C18xrE4C6rFD2WF6XbdoMJFxpBGtX\\\\\\\\\\\\\\\/m8VBfZn7OCeA71twnKaNnEdS76Xn0BvLpYg0QeIkKmQlgro0qPhDaLjC+TsYxmKWrJgK7gTDvFc8QhQ+DdmVpzoCaZGMdK166woxSqWTRFlSxFuPLvhv0LMkfYDtdYvpiqq4M8qPm5tnPoaI9Bx5X3XS5eh05Ayi5oIpfrsA9Kmc+GS9fBF2RAaVMJX6VfLQolkxdqI1n2N3gkuu4QW2PVtSgARVK0Rz7jdy3vKy5gUHcYsKLaw7Zc6k3jBF8FeSZ2rHQxH1QsODMN9yqgi5p410\\\\\\\\\\\\\\\/X3ymBuaGAPfpiM8tmagwyiCvYYTS4gG30RImk2uakWpJ+LKUC9mpHJ7r428i1yCyQYryB3N6zuAQKvKWiw5oZCH092bp\\\\\\\\\\\\\\\/c34S8crrXYQm4Rg54dYVsXLrbAhTLRzS65gjJttiVM+6vC5YSgWUhEfBYC0e5A+Q3HvrhM4jr04goJQ1SxabBh6Vt9Q7Fa6\\\\\\\\\\\\\\\/1qE0nRJbnGer\\\\\\\\\\\\\\\/7stYYpjSg+Bl0Drtc5wweCY2bcr8HjV+rffKSv6eiwRtfJENX4\\\\\\\\\\\\\\\/0cvYpmCq57TwCCHAlF0+O2Lfe9RsV0z+pSSK+qW6kahTuQpjmMMcI5aTp9MggaorZ0o2i0fjKrbCLF2Bp5XtK0vA2\\\\\\\\\\\\\\\/T0V3uPgw2J0V+AUYQcHmKBdbcT9m+aQDdqAXKbXRv3k8D2PGva1D0JkiU0Ah1EFaINR\\\\\\\\\\\\\\\/6rDNIXipLvtYW1Jh0epIHvHzk+rs9lw5CdSNXLU7kjiZ3EdhDIdzmxm3\\\\\\\\\\\\\\\/CuPDkK1fO5khh2Z4cXKGXOOeMqMKn7OlOsyFxAhjwtcPJV2HnV\\\\\\\\\\\\\\\/vHcKhsZjgyKZib3Hdo8cnxh5c9EB93oG3iFq6D\\\\\\\\\\\\\\\/EqizPhN9h\\\\\\\\\\\\\\\/gkDTADzJExjGxukHdusqb7o7\\\\\\\\\\\\\\\/VvMkZhIZjja18TQgStFV5\\\\\\\\\\\\\\\/1gFOa90scTi3\\\\\\\\\\\\\\\/TWNs+wncoraDUBYngM+NXv3EukH8r5\\\\\\\\\\\\\\\/ocFNWIhvMfD1XmQSioWNv68t6kol80dTPF8KuuuJQ7kQisCqxXkwfJrvTRm+BKC5cimGemBKrsd1INv8XEbue\\\\\\\\\\\\\\\/ksim2vr5deGyj3eQ4XOCLdEwBKFKAV0yaWsJE6BHm42FIsre1aI3Vbrkz7e3YhDkGClN4gxkq\\\\\\\\\\\\\\\/qR41GsJexD1Oxdy30fvCS2L52XVsDLTCCOd4PLlEnsAYWfNDHGfr5QgVqTqLjY6+fq0SdwAqKPCkkiIkC04BqYv2nESKIhj\\\\\\\\\\\\\\\/IQ5EY1F9SI36Ii\\\\\\\\\\\\\\\/jhX6MXSXJ4FWH2ULq+p4Hr4JbbA4qJMitb0IraxIn47yQNqS1wF9IUl6tR0r6HhbvFR7YOMs9T4mpxCDhQSo\\\\\\\\\\\\\\\/hWtRaD9EeztUPyDcB2K1+hWxOyXzzfzSDKGqBDfnY3KsvnNUIPcFgX+IoHKbcEOiIo37zAndWSEGd9oepIIhTU0ZmgpRCGE945qp1OBxCZBwec46nB2IJ2IjZhuiTczzwgc+5dOGF1xiS\\\\\\\\\\\\\\\/WPCEOdbK1iI2HCnMSboM0\\\\\\\\\\\\\\\/9MJD8Hf\\\\\\\\\\\\\\\/vPpminZx0NDVgzDvOj7SIN+fbqfc8QgF7bHSWPfUt5VKRyEBP6rFqCMFh0+pDiAclT1PFs4jpyz36U504UKYV1yreNWlm3jtFkeoOdtAOs0LO77mENqJPBg7Tvy2VJcbnBXsz9dcOx2wLvGxaLj\\\\\\\\\\\\\\\/JzhggLb+dJjd6TF6MJZjFxtefqPHT32d1j+dxKK\\\\\\\\\\\\\\\/mXWBTihnx3ycQff9697Mp0CsQrfwn1aIyLZxyvMolxfIEUoAuf53IrusqaCFufxe1FeC5vvus1jAURnytKCG+bb\\\\\\\\\\\\\\\/0Bt6qblUrAgLQROaawxWFhSGHeWwZKSRpFEmiMCSuz5h41hQr6RtXuysMqd+1E3\\\\\\\\\\\\\\\/eah0tEnS3bR8KzNVXjIt6q7bnZSeu8DxCb56zQis0Jd6DFJTabRH4X39VLpvrd0c7m32lZb9nZ07oJJIU4KtV+NtvAPtRGpcZjJK\\\\\\\\\\\\\\\/5X+vbj\\\\\\\\\\\\\\\/B65zwdcXiB8JCaL0LH3+tRFLjYqK07DpigWbAqnEojKeiIybUMNPNv+WzcRyFDshvX8fBzMjIzwkC3QaHmLhbi5ExYPlgf1DMUfJv32kw5Uhs=\\\\\\u0022,\\\\\\u0022iv\\\\\\u0022:\\\\\\u0022Hl3fvVmqXdKVnsEzllWL5A==\\\\\\u0022,\\\\\\u0022salt\\\\\\u0022:\\\\\\u00223fcf69c0544933648ca27e63b3137e55\\\\\\u0022}\\u0022,\\u0022hmac\\u0022:\\u00225d4bc0980a60067b8e6d2ca6613f0b557e5da65b612b9f8b8b61422e08d09d17\\u0022}\u0022},\u0022highwire\u0022:{\u0022ac\u0022:{\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A133.2.atom\u0022:{\u0022access\u0022:{\u0022reprint\u0022:true,\u0022abstract\u0022:true},\u0022pisa_id\u0022:\u0022\u0022,\u0022apath\u0022:\u0022\\\/jitc\\\/8\\\/Suppl_3\\\/A133.2.atom\u0022,\u0022jcode\u0022:\u0022jitc\u0022}}},\u0022MutationObserver\u0022:{\u0022js\u0022:\u0022\\\/sites\\\/all\\\/libraries\\\/mutationobserver\\\/MutationObserver.js\u0022},\u0022ajaxPageState\u0022:{\u0022js\u0022:{\u00220\u0022:1,\u0022https:\\\/\\\/d1bxh8uas1mnw7.cloudfront.net\\\/assets\\\/embed.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/highwire\\\/highwire\\\/plugins\\\/content_types\\\/js\\\/highwire_altmetrics.js\u0022:1,\u0022sites\\\/all\\\/modules\\\/contrib\\\/panels_ajax_pane\\\/panels_ajax_pane.js\u0022:1}}});\n\/\/--\u003E\u003C!]]\u003E\n\u003C\/script\u003E\u003Clink type=\u0022text\/css\u0022 rel=\u0022stylesheet\u0022 href=\u0022\/\/www.highwirestage.com\/sites\/default\/files\/advagg_css\/css__dn-cpI1YtkU_iLHgA5WhlkxgYWyat_IxjF_B-WSYrpE__a9hIbt0eaZ7d5nhwnm2weG8R_2eXK4EvoOx9dOxouHE__3qvfz4I9k5oUIeimOjbmdyh6ZgM-xweyVc5gub1_nR4.css\u0022 media=\u0022all\u0022\u003E\u003Clink rel=\u0022stylesheet\u0022 type=\u0022text\/css\u0022 href=\u0022\/sites\/all\/modules\/contrib\/panels\/plugins\/layouts\/onecol\/onecol.css\u0022\u003E\u003C\/head\u003E\u003Cbody\u003E\u003Cdiv class=\u0022panels-ajax-tab-panel panels-ajax-tab-panel-jnl-template-bmjj-tab-art\u0022\u003E\u003Cdiv class=\u0022panel-display panel-1col clearfix\u0022\u003E\n  \u003Cdiv class=\u0022panel-panel panel-col\u0022\u003E\n    \u003Cdiv\u003E\u003Cdiv class=\u0022panel-pane pane-dfp-pane oas-ads oas-ads-mid pull-right\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv id=\u0022dfp-ad-mpu-wrapper\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n\n\u003Cdiv id=\u0022dfp-ad-mpu\u0022 class=\u0022dfp-tag-wrapper\u0022\u003E\n  \u003Cscript type=\u0022text\/javascript\u0022\u003E\n    googletag.cmd.push(function() {\n      googletag.display(\u0022dfp-ad-mpu\u0022);\n    });\n  \u003C\/script\u003E\u003C\/div\u003E\n\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-1\u0022\u003E\n  \n      \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003E\u003Ca href=\u0022https:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0224\u0022 target=\u0022_new\u0022\u003Ehttps:\/\/doi.org\/10.1136\/jitc-2020-SITC2020.0224\u003C\/a\u003E\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-highwire-altmetrics\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003EStatistics from Altmetric.com\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv data-badge-details=\u0022right\u0022 data-badge-type=\u0022medium-donut\u0022 data-doi=\u002210.1136\/jitc-2020-SITC2020.0224\u0022 data-hide-no-mentions=\u0022true\u0022 class=\u0022altmetric-embed\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-custom pane-2 permissions-box\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003ERequest Permissions\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cp\u003EIf you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center\u0026rsquo;s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.\u003C\/p\u003E\n  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003Cdiv class=\u0022panel-separator\u0022\u003E\u003C\/div\u003E\u003Cdiv class=\u0022panel-pane pane-panels-ajax-pane-content permissions-box pane-highwire-permission-link\u0022 id=\u0022request-permissions\u0022\u003E\n  \n        \u003Ch2 class=\u0022pane-title\u0022\u003E\u003Cspan class=\u0022panels-ajax-pane-title\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/span\u003E\u003C\/h2\u003E\n    \n  \n  \u003Cdiv class=\u0022pane-content\u0022\u003E\n    \u003Cdiv class=\u0022panels-ajax-pane panels-ajax-pane-new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022 data-pid=\u0022new-70fd4c70-563e-4b94-ae3b-2a97f3980c13\u0022\u003E\u003C\/div\u003E  \u003C\/div\u003E\n\n  \n  \u003C\/div\u003E\n\u003C\/div\u003E\n  \u003C\/div\u003E\n\u003C\/div\u003E\n\u003C\/div\u003E\u003C\/body\u003E\u003C\/html\u003E\n"}